Gene description for BAZ1A
Gene name bromodomain adjacent to zinc finger domain, 1A
Gene symbol BAZ1A
Other names/aliases ACF1
WALp1
WCRF180
hACF1
Species Homo sapiens
 Database cross references - BAZ1A
ExoCarta ExoCarta_11177
Vesiclepedia VP_11177
Entrez Gene 11177
HGNC 960
MIM 605680
UniProt Q9NRL2  
 BAZ1A identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for BAZ1A
Molecular Function
    DNA binding GO:0003677 IBA
    histone acetyltransferase activity GO:0004402 TAS
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    DNA-templated DNA replication GO:0006261 IDA
    regulation of DNA replication GO:0006275 IMP
    nucleosome assembly GO:0006334 IDA
    chromatin remodeling GO:0006338 IDA
    chromatin remodeling GO:0006338 TAS
    regulation of DNA-templated transcription GO:0006355 IBA
    regulation of transcription by RNA polymerase II GO:0006357 NAS
    regulation of heterochromatin formation GO:0031445 IBA
    positive regulation of DNA replication GO:0045740 IBA
    positive regulation of DNA replication GO:0045740 IMP
Subcellular Localization
    nuclear chromosome GO:0000228 IBA
    nucleus GO:0005634 IDA
    pericentric heterochromatin GO:0005721 EXP
    pericentric heterochromatin GO:0005721 ISO
    CHRAC GO:0008623 IBA
    CHRAC GO:0008623 IDA
    CHRAC GO:0008623 NAS
    ACF complex GO:0016590 IPI
    ACF complex GO:0016590 TAS
 Experiment description of studies that identified BAZ1A in sEVs
1
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for BAZ1A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 DZIP3  
Affinity Capture-MS Homo sapiens
3 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
4 GRK5 2869
Affinity Capture-MS Homo sapiens
5 MECP2 4204
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 POLR1E  
Affinity Capture-MS Homo sapiens
7 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
8 CHRAC1  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
9 PARP1 142
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 HIST1H3A 8350
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
11 MTA2 9219
Co-fractionation Homo sapiens
12 KPNA1 3836
Affinity Capture-MS Homo sapiens
13 SMARCAD1  
Affinity Capture-MS Homo sapiens
14 MAX  
Affinity Capture-MS Homo sapiens
15 Cebpb  
Affinity Capture-Western Rattus norvegicus
Reconstituted Complex Rattus norvegicus
16 BAZ1B 9031
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
17 UGGT1 56886
Affinity Capture-MS Homo sapiens
18 SMARCA5 8467
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
19 H2AFZ 3015
Affinity Capture-MS Homo sapiens
20 FGFBP1 9982
Affinity Capture-MS Homo sapiens
21 HIST1H2BG 8339
Proximity Label-MS Homo sapiens
22 HMGA1 3159
Affinity Capture-MS Homo sapiens
23 POLE3  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
24 HMGN5 79366
Affinity Capture-MS Homo sapiens
25 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
26 HIST1H2BB 3018
Affinity Capture-Western Homo sapiens
27 NUMA1 4926
Affinity Capture-MS Homo sapiens
28 MTNR1A  
Two-hybrid Homo sapiens
29 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
30 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
31 HMGN2 3151
Affinity Capture-MS Homo sapiens
32 FOXL1  
Affinity Capture-MS Homo sapiens
33 SUMO2 6613
Reconstituted Complex Homo sapiens
34 RBBP4 5928
Co-fractionation Homo sapiens
35 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
36 CENPA  
Proximity Label-MS Homo sapiens
37 CAPN6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
38 APEX1 328
Affinity Capture-RNA Homo sapiens
Proximity Label-MS Homo sapiens
39 C9orf78 51759
Affinity Capture-MS Homo sapiens
40 TBC1D32 221322
Proximity Label-MS Homo sapiens
41 NCOR1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
42 TOP1 7150
Cross-Linking-MS (XL-MS) Homo sapiens
43 SMAD2 4087
Two-hybrid Homo sapiens
44 SMAD9  
Two-hybrid Homo sapiens
45 BRCC3 79184
Co-fractionation Homo sapiens
46 SMARCA1 6594
Affinity Capture-MS Homo sapiens
47 FBXL6  
Affinity Capture-MS Homo sapiens
48 TEAD2  
Affinity Capture-MS Homo sapiens
49 ANOS1 3730
Affinity Capture-MS Homo sapiens
50 XRCC6 2547
Reconstituted Complex Homo sapiens
51 YWHAQ 10971
Affinity Capture-MS Homo sapiens
52 SMARCA2 6595
Affinity Capture-Western Homo sapiens
53 CCDC22 28952
Affinity Capture-MS Homo sapiens
54 BMI1  
Affinity Capture-MS Homo sapiens
55 Nedd1  
Affinity Capture-MS Mus musculus
56 HECTD1 25831
Affinity Capture-MS Homo sapiens
57 YWHAG 7532
Affinity Capture-MS Homo sapiens
58 POLR1D 51082
Affinity Capture-MS Homo sapiens
59 MBD3 53615
Co-fractionation Homo sapiens
60 NUCKS1 64710
Affinity Capture-MS Homo sapiens
61 RHOA 387
Affinity Capture-MS Homo sapiens
62 FOXE1  
Affinity Capture-MS Homo sapiens
63 RPA3 6119
Proximity Label-MS Homo sapiens
64 ZNF467  
Affinity Capture-MS Homo sapiens
65 BRD3 8019
Affinity Capture-MS Homo sapiens
66 Chmp4b 75608
Affinity Capture-MS Mus musculus
67 PYHIN1  
Affinity Capture-MS Homo sapiens
68 RAD21 5885
Co-fractionation Homo sapiens
69 XRCC5 7520
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
70 CCDC8  
Affinity Capture-MS Homo sapiens
71 SATB1 6304
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
72 H2AFX 3014
Affinity Capture-Western Homo sapiens
View the network image/svg+xml
 Pathways in which BAZ1A is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here