Gene description for TBC1D32
Gene name TBC1 domain family, member 32
Gene symbol TBC1D32
Other names/aliases BROMI
C6orf170
C6orf171
bA301B7.2
bA57L9.1
dJ310J6.1
Species Homo sapiens
 Database cross references - TBC1D32
ExoCarta ExoCarta_221322
Vesiclepedia VP_221322
Entrez Gene 221322
HGNC 21485
MIM 615867
UniProt Q96NH3  
 TBC1D32 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for TBC1D32
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    kidney development GO:0001822 IEA
    lens development in camera-type eye GO:0002088 IEA
    retinal pigment epithelium development GO:0003406 IEA
    determination of left/right symmetry GO:0007368 IEA
    heart development GO:0007507 IEA
    embryonic digit morphogenesis GO:0042733 IEA
    roof of mouth development GO:0060021 IEA
    smoothened signaling pathway involved in dorsal/ventral neural tube patterning GO:0060831 IEA
    protein localization to cilium GO:0061512 IEA
    non-motile cilium assembly GO:1905515 IBA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    cilium GO:0005929 IEA
 Experiment description of studies that identified TBC1D32 in exosomes
1
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for TBC1D32
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CFAP20 29105
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 AFG3L2 10939
Proximity Label-MS Homo sapiens
3 UQCRFS1 7386
Proximity Label-MS Homo sapiens
4 TIMM21  
Proximity Label-MS Homo sapiens
5 STT3A 3703
Proximity Label-MS Homo sapiens
6 SRPRB 58477
Proximity Label-MS Homo sapiens
7 FOXJ1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 UXT 8409
Proximity Label-MS Homo sapiens
9 NDUFA4 4697
Proximity Label-MS Homo sapiens
10 SENP3 26168
Proximity Label-MS Homo sapiens
11 HSD17B12 51144
Proximity Label-MS Homo sapiens
12 TOMM22 56993
Proximity Label-MS Homo sapiens
13 NUDCD2 134492
Proximity Label-MS Homo sapiens
14 ATP5D 513
Proximity Label-MS Homo sapiens
15 DPM1 8813
Proximity Label-MS Homo sapiens
16 NAV1 89796
Proximity Label-MS Homo sapiens
17 SMARCA1 6594
Proximity Label-MS Homo sapiens
18 RRM2B 50484
Proximity Label-MS Homo sapiens
19 ERC1 23085
Proximity Label-MS Homo sapiens
20 TDP2 51567
Proximity Label-MS Homo sapiens
21 SFXN4  
Proximity Label-MS Homo sapiens
22 ARL1 400
Proximity Label-MS Homo sapiens
23 MYCN  
Affinity Capture-MS Homo sapiens
24 ESYT2 57488
Proximity Label-MS Homo sapiens
25 MAD2L1 4085
Proximity Label-MS Homo sapiens
26 FAR1 84188
Proximity Label-MS Homo sapiens
27 BAG5 9529
Proximity Label-MS Homo sapiens
28 UBR4 23352
Proximity Label-MS Homo sapiens
29 SLC25A10 1468
Proximity Label-MS Homo sapiens
30 LANCL1 10314
Proximity Label-MS Homo sapiens
31 LIN28B  
Proximity Label-MS Homo sapiens
32 ACOT9 23597
Proximity Label-MS Homo sapiens
33 CENPV 201161
Proximity Label-MS Homo sapiens
34 RAB21 23011
Proximity Label-MS Homo sapiens
35 ILVBL 10994
Proximity Label-MS Homo sapiens
36 BAG6 7917
Proximity Label-MS Homo sapiens
37 ABCF2 10061
Proximity Label-MS Homo sapiens
38 MKRN2 23609
Proximity Label-MS Homo sapiens
39 RFX3 5991
Affinity Capture-MS Homo sapiens
40 MPDU1 9526
Proximity Label-MS Homo sapiens
41 UBE2D3 7323
Proximity Label-MS Homo sapiens
42 AP3B1 8546
Proximity Label-MS Homo sapiens
43 TMEM33 55161
Proximity Label-MS Homo sapiens
44 XYLT2 64132
Affinity Capture-MS Homo sapiens
45 RHOT2 89941
Proximity Label-MS Homo sapiens
46 CDIPT 10423
Proximity Label-MS Homo sapiens
47 RAB6A 5870
Proximity Label-MS Homo sapiens
48 CDK7 1022
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
49 DHCR7 1717
Proximity Label-MS Homo sapiens
50 ATP2B1 490
Proximity Label-MS Homo sapiens
51 KCMF1 56888
Proximity Label-MS Homo sapiens
52 NR3C1 2908
Proximity Label-MS Homo sapiens
53 FKBP8 23770
Proximity Label-MS Homo sapiens
54 SLC7A5 8140
Proximity Label-MS Homo sapiens
55 GADD45GIP1  
Proximity Label-MS Homo sapiens
56 AP2M1 1173
Proximity Label-MS Homo sapiens
57 AURKB 9212
Proximity Label-MS Homo sapiens
58 MAP7D1 55700
Proximity Label-MS Homo sapiens
59 ACSL3 2181
Proximity Label-MS Homo sapiens
60 MYC  
Affinity Capture-MS Homo sapiens
61 DNAJC9 23234
Proximity Label-MS Homo sapiens
62 BAZ1A 11177
Proximity Label-MS Homo sapiens
63 NDUFA10 4705
Proximity Label-MS Homo sapiens
64 HAX1  
Proximity Label-MS Homo sapiens
65 FAM149B1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 DLAT 1737
Proximity Label-MS Homo sapiens
67 SLC9A6 10479
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 RAB18 22931
Proximity Label-MS Homo sapiens
69 SUGT1 10910
Proximity Label-MS Homo sapiens
70 ATP6  
Proximity Label-MS Homo sapiens
71 SVIL 6840
Proximity Label-MS Homo sapiens
72 MRPS2 51116
Proximity Label-MS Homo sapiens
73 URI1  
Proximity Label-MS Homo sapiens
74 C9orf114  
Proximity Label-MS Homo sapiens
75 WDR92 116143
Proximity Label-MS Homo sapiens
76 FANCI 55215
Proximity Label-MS Homo sapiens
77 HDAC1 3065
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
78 YTHDF3  
Proximity Label-MS Homo sapiens
79 SFXN1 94081
Proximity Label-MS Homo sapiens
80 SFSWAP  
Affinity Capture-MS Homo sapiens
81 RBFOX2 23543
Proximity Label-MS Homo sapiens
82 NAMPT 10135
Proximity Label-MS Homo sapiens
83 HSPBP1 23640
Proximity Label-MS Homo sapiens
84 DHFR 1719
Proximity Label-MS Homo sapiens
85 KDELR2 11014
Proximity Label-MS Homo sapiens
86 DNAH10 196385
Proximity Label-MS Homo sapiens
87 UHRF1 29128
Proximity Label-MS Homo sapiens
88 MRPS22 56945
Proximity Label-MS Homo sapiens
89 TIMM44 10469
Proximity Label-MS Homo sapiens
90 SCO2  
Proximity Label-MS Homo sapiens
91 SEC61A1 29927
Proximity Label-MS Homo sapiens
View the network image/svg+xml
 Pathways in which TBC1D32 is involved
No pathways found





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