Gene description for TBC1D32
Gene name TBC1 domain family, member 32
Gene symbol TBC1D32
Other names/aliases BROMI
C6orf170
C6orf171
bA301B7.2
bA57L9.1
dJ310J6.1
Species Homo sapiens
 Database cross references - TBC1D32
ExoCarta ExoCarta_221322
Entrez Gene 221322
HGNC 21485
MIM 615867
UniProt Q96NH3  
 TBC1D32 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for TBC1D32
Biological Process
    embryonic digit morphogenesis GO:0042733 IEA
    lens development in camera-type eye GO:0002088 IEA
    smoothened signaling pathway involved in dorsal/ventral neural tube patterning GO:0060831 IEA
    retinal pigment epithelium development GO:0003406 IEA
    cilium morphogenesis GO:0060271 IEA
    protein localization to cilium GO:0061512 IEA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    cilium GO:0005929 IEA
 Experiment description of studies that identified TBC1D32 in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for TBC1D32
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which TBC1D32 is involved
No pathways found





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