Gene description for CENPV
Gene name centromere protein V
Gene symbol CENPV
Other names/aliases 3110013H01Rik
CENP-V
PRR6
p30
Species Homo sapiens
 Database cross references - CENPV
ExoCarta ExoCarta_201161
Entrez Gene 201161
HGNC 29920
MIM 608139
UniProt Q7Z7K6  
 CENPV identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
Thymus 23844026    
 Gene ontology annotations for CENPV
Molecular Function
    carbon-sulfur lyase activity GO:0016846 IEA
    molecular_function GO:0003674 ND
Biological Process
    pericentric heterochromatin assembly GO:0031508 IMP
    ameboidal-type cell migration GO:0001667 IDA
    centromere complex assembly GO:0034508 IMP
    cell division GO:0051301 IEA
    mitotic nuclear division GO:0007067 IEA
    regulation of chromosome organization GO:0033044 IMP
    positive regulation of cytokinesis GO:0032467 IMP
    metabolic process GO:0008152 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IDA
    nucleus GO:0005634 IDA
    microtubule cytoskeleton GO:0015630 IDA
    condensed chromosome kinetochore GO:0000777 IEA
    cytoplasm GO:0005737 IDA
    spindle midzone GO:0051233 IDA
    kinetochore GO:0000776 IDA
 Experiment description of studies that identified CENPV in exosomes
1
Experiment ID 237
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
2
Experiment ID 217
ISEV standards
EM
EV Biophysical techniques
TSG101
EV Cytosolic markers
CD81|CD9|CD63
EV Membrane markers
EV Negative markers
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CENPV
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MOS 4342
Invivo Homo sapiens
View the network image/svg+xml
 Pathways in which CENPV is involved
No pathways found





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