Gene description for TUBA1B
Gene name tubulin, alpha 1b
Gene symbol TUBA1B
Other names/aliases K-ALPHA-1
Species Homo sapiens
 Database cross references - TUBA1B
ExoCarta ExoCarta_10376
Vesiclepedia VP_10376
Entrez Gene 10376
HGNC 18809
MIM 602530
UniProt P68363  
 TUBA1B identified in sEVs derived from the following tissue/cell type
B cells 12519789    
B cells 20458337    
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 22740476    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Lung cancer cells 35136055    
Lung cancer cells 35136055    
Lung cancer cells 35136055    
Lung epithelial cells 35136055    
Lung epithelial cells 35136055    
Lung epithelial cells 35136055    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 22723089    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for TUBA1B
Molecular Function
    double-stranded RNA binding GO:0003725 IDA
    GTPase activity GO:0003924 IDA
    structural molecule activity GO:0005198 TAS
    structural constituent of cytoskeleton GO:0005200 IBA
    structural constituent of cytoskeleton GO:0005200 IDA
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IBA
    GTP binding GO:0005525 IDA
    ubiquitin protein ligase binding GO:0031625 IPI
Biological Process
    microtubule cytoskeleton organization GO:0000226 IBA
    microtubule cytoskeleton organization GO:0000226 IDA
    mitotic cell cycle GO:0000278 IBA
    microtubule-based process GO:0007017 TAS
    cytoskeleton-dependent intracellular transport GO:0030705 TAS
    cell division GO:0051301 TAS
    cellular response to interleukin-4 GO:0071353 IEA
Subcellular Localization
    cytoplasm GO:0005737 IBA
    microtubule GO:0005874 IBA
    microtubule GO:0005874 IDA
    microtubule GO:0005874 TAS
    cytoplasmic microtubule GO:0005881 IEA
    microtubule cytoskeleton GO:0015630 IDA
    microtubule cytoskeleton GO:0015630 IDA
 Experiment description of studies that identified TUBA1B in sEVs
1
Experiment ID 11
MISEV standards
✘ Biophysical techniques
✔
HSC70|HSP90|MHCII|CD63|CD81
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [MALDI TOF]
PubMed ID 12519789    
Organism Homo sapiens
Experiment description Proteomic and biochemical analyses of human B cell-derived exosomes. Potential implications for their function and multivesicular body formation.
Authors "Wubbolts R, Leckie RS, Veenhuizen PT, Schwarzmann G, Mobius W, Hoernschemeyer J, Slot JW, Geuze HJ, Stoorvogel W"
Journal name JBC
Publication year 2003
Sample B cells
Sample name RN (HLA-DR15+)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [MALDI TOF]
Mass spectrometry [QTOF]
Western blotting
Thin layer chromatography
HPLC
2
Experiment ID 79
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 1
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 80
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
4
Experiment ID 81
MISEV standards
✘ Biophysical techniques
✔
CD81|MHCII
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
5
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
6
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
11
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
12
Experiment ID 201
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22740476    
Organism Homo sapiens
Experiment description Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Authors "Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ."
Journal name Electrophoresis
Publication year 2012
Sample Colorectal cancer cells
Sample name SW480
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
13
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
14
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
15
Experiment ID 285
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
16
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
17
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
18
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
19
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
22
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
23
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
24
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
25
Experiment ID 731
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|SDCBP
Enriched markers
✔
GOLGA2|TUBA1A
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 35136055    
Organism Homo sapiens
Experiment description "Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells"
Authors "Kim O, Hwangbo C, Tran PT, Lee JH."
Journal name Cell Death Dis
Publication year 2022
Sample Lung cancer cells
Sample name NCI-H226
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
miRNA array
26
Experiment ID 732
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|SDCBP
Enriched markers
✔
GOLGA2|TUBA1A
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 35136055    
Organism Homo sapiens
Experiment description "Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells"
Authors "Kim O, Hwangbo C, Tran PT, Lee JH."
Journal name Cell Death Dis
Publication year 2022
Sample Lung cancer cells
Sample name NCI-H226
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
miRNA array
27
Experiment ID 738
MISEV standards
✘ Biophysical techniques
✔
TSG101|SDCBP
Enriched markers
✔
TUBA1A
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 35136055    
Organism Homo sapiens
Experiment description "Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells"
Authors "Kim O, Hwangbo C, Tran PT, Lee JH."
Journal name Cell Death Dis
Publication year 2022
Sample Lung cancer cells
Sample name NCI-H1703
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
RT-qPCR
28
Experiment ID 740
MISEV standards
✘ Biophysical techniques
✔
SDCBP
Enriched markers
✔
TUBA1A
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 35136055    
Organism Homo sapiens
Experiment description "Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells"
Authors "Kim O, Hwangbo C, Tran PT, Lee JH."
Journal name Cell Death Dis
Publication year 2022
Sample Lung epithelial cells
Sample name BEAS-2B
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
29
Experiment ID 741
MISEV standards
✘ Biophysical techniques
✔
SDCBP
Enriched markers
✔
TUBA1A
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 35136055    
Organism Homo sapiens
Experiment description "Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells"
Authors "Kim O, Hwangbo C, Tran PT, Lee JH."
Journal name Cell Death Dis
Publication year 2022
Sample Lung epithelial cells
Sample name BEAS-2B
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
30
Experiment ID 742
MISEV standards
✘ Biophysical techniques
✔
SDCBP
Enriched markers
✔
TUBA1A
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 35136055    
Organism Homo sapiens
Experiment description "Syntenin-1-mediated small extracellular vesicles promotes cell growth, migration, and angiogenesis by increasing onco-miRNAs secretion in lung cancer cells"
Authors "Kim O, Hwangbo C, Tran PT, Lee JH."
Journal name Cell Death Dis
Publication year 2022
Sample Lung epithelial cells
Sample name BEAS-2B
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
31
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
32
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
33
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
Western blotting
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 126
MISEV standards
✘ Biophysical techniques
✔
GAPDH
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
39
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
40
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
41
Experiment ID 231
MISEV standards
✘ Biophysical techniques
✔
Alix|CD63|CD9
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
42
Experiment ID 232
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 233
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
44
Experiment ID 138
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
45
Experiment ID 139
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name DU145 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
46
Experiment ID 140
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
47
Experiment ID 141
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name VCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
48
Experiment ID 142
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name LNCaP - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
49
Experiment ID 143
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|LAMP2|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name LNCaP - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
50
Experiment ID 144
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD9
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 2
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
51
Experiment ID 145
MISEV standards
✔
EM
Biophysical techniques
✔
HSP70|HSP90|RAB5|CD10
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry [QTOF]   
PubMed ID 22723089    
Organism Homo sapiens
Experiment description Prostate cancer cell derived exosomes
Authors "Hosseini-Beheshti E, Guns ES."
Journal name MCP
Publication year 2012
Sample Prostate cancer cells
Sample name C4-2 - Rep 3
Isolation/purification methods Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
52
Experiment ID 275
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
53
Experiment ID 274
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
✔
AIF
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
54
Experiment ID 196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
55
Experiment ID 197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for TUBA1B
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PTPRF 5792
Two-hybrid Homo sapiens
2 RIT1 6016
Negative Genetic Homo sapiens
3 CSTL1  
Affinity Capture-MS Homo sapiens
4 HNRNPC 3183
Co-fractionation Homo sapiens
5 PPP3CA 5530
Affinity Capture-MS Homo sapiens
6 KPNA3 3839
Co-fractionation Homo sapiens
7 UBL4A 8266
Affinity Capture-MS Homo sapiens
8 SHC1 6464
Affinity Capture-MS Homo sapiens
9 CCT5 22948
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 PFDN4 5203
Affinity Capture-MS Homo sapiens
11 KDM5C  
Affinity Capture-MS Homo sapiens
12 RIN3  
Affinity Capture-MS Homo sapiens
13 SKI 6497
Affinity Capture-MS Homo sapiens
14 TARDBP 23435
Affinity Capture-MS Homo sapiens
15 SP1  
Affinity Capture-MS Homo sapiens
16 PRSS3 5646
Affinity Capture-MS Homo sapiens
17 EBNA-LP  
Affinity Capture-Western
Co-purification
18 GNS 2799
Co-fractionation Homo sapiens
19 TUBB8 347688
Affinity Capture-MS Homo sapiens
20 TMEM253  
Two-hybrid Homo sapiens
21 MAP4 4134
Affinity Capture-MS Homo sapiens
22 UBE3A 7337
Affinity Capture-MS Homo sapiens
23 CCT4 10575
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
24 LAMP2 3920
Co-fractionation Homo sapiens
25 CSTA 1475
Affinity Capture-MS Homo sapiens
26 CCT6B 10693
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
27 TROVE2 6738
Co-fractionation Homo sapiens
28 MID1 4281
Affinity Capture-MS Homo sapiens
29 KDM4A  
Affinity Capture-MS Homo sapiens
30 ZBTB1  
Affinity Capture-MS Homo sapiens
31 RPS6KB2  
Affinity Capture-MS Homo sapiens
32 AFTPH  
Affinity Capture-MS Homo sapiens
33 SOX2  
Affinity Capture-MS Homo sapiens
34 CEP97 79598
Affinity Capture-MS Homo sapiens
35 TACC2 10579
Affinity Capture-MS Homo sapiens
36 CD247 919
Affinity Capture-Western Homo sapiens
37 DNAJB6 10049
Affinity Capture-MS Homo sapiens
38 APEX1 328
Affinity Capture-RNA Homo sapiens
39 ASB17  
Affinity Capture-MS Homo sapiens
40 POLH  
Affinity Capture-MS Homo sapiens
41 CUL7 9820
Affinity Capture-MS Homo sapiens
42 HYAL1 3373
Affinity Capture-MS Homo sapiens
43 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
44 WDR76  
Affinity Capture-MS Homo sapiens
45 CCT6A 908
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 B3GNT2 10678
Affinity Capture-MS Homo sapiens
47 TUBB 203068
Co-fractionation Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
48 VARS 7407
Co-fractionation Homo sapiens
49 SF3B1 23451
Co-fractionation Homo sapiens
50 CENPV 201161
Affinity Capture-Western Homo sapiens
51 FANCM 57697
Affinity Capture-MS Homo sapiens
52 PLK4  
Affinity Capture-MS Homo sapiens
53 FBXW7  
Synthetic Lethality Homo sapiens
54 IQGAP1 8826
Co-fractionation Homo sapiens
55 LGR4 55366
Affinity Capture-MS Homo sapiens
56 PIWIL1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
57 KLRC1  
Affinity Capture-MS Homo sapiens
58 MTMR2 8898
Affinity Capture-MS Homo sapiens
59 OBSL1 23363
Affinity Capture-MS Homo sapiens
60 SMC2 10592
Co-fractionation Homo sapiens
61 Yap1  
Reconstituted Complex Mus musculus
62 TOM1L1 10040
Two-hybrid Homo sapiens
63 MID2 11043
Affinity Capture-MS Homo sapiens
64 VAPB 9217
Affinity Capture-MS Homo sapiens
65 FAM135A  
Affinity Capture-MS Homo sapiens
66 CHORDC1 26973
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
67 EED  
Affinity Capture-MS Homo sapiens
68 SLX4  
Affinity Capture-MS Homo sapiens
69 HNRNPA1 3178
Co-fractionation Homo sapiens
70 TUBA4A 7277
Affinity Capture-MS Homo sapiens
71 VCAM1 7412
Affinity Capture-MS Homo sapiens
72 TERT  
Two-hybrid Homo sapiens
73 DCD 117159
Affinity Capture-MS Homo sapiens
74 TUBB6 84617
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
75 TFCP2 7024
Affinity Capture-MS Homo sapiens
76 ARIH2 10425
Affinity Capture-MS Homo sapiens
77 SMYD4  
Affinity Capture-MS Homo sapiens
78 PFDN6 10471
Affinity Capture-MS Homo sapiens
79 FAF2 23197
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 FGFR1 2260
Affinity Capture-MS Homo sapiens
81 FKBPL  
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
82 RLIM 51132
Affinity Capture-MS Homo sapiens
83 MSL3  
Affinity Capture-MS Homo sapiens
84 PCNA 5111
Co-fractionation Homo sapiens
85 HSPA8 3312
Affinity Capture-MS Homo sapiens
86 FOXP1 27086
Protein-RNA Homo sapiens
87 LIN28A  
Affinity Capture-MS Homo sapiens
88 CCT2 10576
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
89 XPO1 7514
Affinity Capture-MS Homo sapiens
90 TCP1 6950
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
91 AGTRAP 57085
Two-hybrid Homo sapiens
92 SNRNP70 6625
Co-fractionation Homo sapiens
93 EML4 27436
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
94 KDM6A  
Affinity Capture-MS Homo sapiens
95 RBX1 9978
Affinity Capture-MS Homo sapiens
96 PARK2  
Affinity Capture-MS Homo sapiens
97 MAP1B 4131
Co-fractionation Homo sapiens
98 ERBB3 2065
Affinity Capture-MS Homo sapiens
99 ITGAD  
Affinity Capture-MS Homo sapiens
100 SUPT5H 6829
Affinity Capture-MS Homo sapiens
101 Cct7 12468
Affinity Capture-MS Mus musculus
102 A2M 2
Two-hybrid Homo sapiens
103 TUBA1A 7846
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 PSMD14 10213
Affinity Capture-MS Homo sapiens
105 EEF1G 1937
Co-fractionation Homo sapiens
106 RAD51  
Affinity Capture-MS Homo sapiens
107 CAPSL  
Affinity Capture-MS Homo sapiens
108 SNRNP200 23020
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
109 RPL5 6125
Co-fractionation Homo sapiens
110 TUBB2B 347733
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
111 UBASH3B 84959
Affinity Capture-MS Homo sapiens
112 MAPT  
Reconstituted Complex Homo sapiens
113 DEK 7913
Co-fractionation Homo sapiens
114 PDCD5 9141
Affinity Capture-MS Homo sapiens
115 TUBA1C 84790
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
116 TNPO2 30000
Co-fractionation Homo sapiens
117 YAP1 10413
Affinity Capture-MS Homo sapiens
118 MYH9 4627
Co-fractionation Homo sapiens
119 ESRRB  
Affinity Capture-MS Homo sapiens
120 OGT 8473
Reconstituted Complex Homo sapiens
121 RAD1  
Affinity Capture-MS Homo sapiens
122 EFNA3  
Affinity Capture-MS Homo sapiens
123 IFI16 3428
Affinity Capture-MS Homo sapiens
124 U2AF2 11338
Co-fractionation Homo sapiens
125 RAD18  
Affinity Capture-MS Homo sapiens
126 SUMO2 6613
Reconstituted Complex Homo sapiens
127 DNAJA1 3301
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
128 SEMG1 6406
Affinity Capture-MS Homo sapiens
129 SMAD2 4087
Reconstituted Complex Homo sapiens
130 GCC2 9648
Affinity Capture-MS Homo sapiens
131 DHFRL1  
Affinity Capture-MS Homo sapiens
132 SLAIN1 122060
Affinity Capture-MS Homo sapiens
133 PIK3R1 5295
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
134 CEP76  
Affinity Capture-MS Homo sapiens
135 RPLP0P6 220717
Co-fractionation Homo sapiens
136 VCPIP1 80124
Affinity Capture-MS Homo sapiens
137 MICU1 10367
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 H2AFY 9555
Co-fractionation Homo sapiens
139 KCNH5  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
140 KDM5A  
Affinity Capture-MS Homo sapiens
141 U2AF1 7307
Co-fractionation Homo sapiens
142 UBXN6 80700
Affinity Capture-MS Homo sapiens
143 ID2  
Affinity Capture-MS Homo sapiens
144 EML1 2009
Affinity Capture-Western Homo sapiens
145 FBXL4 26235
Affinity Capture-MS Homo sapiens
146 ATG16L1 55054
Affinity Capture-MS Homo sapiens
147 GAN 8139
Affinity Capture-MS Homo sapiens
148 BACE2 25825
Affinity Capture-MS Homo sapiens
149 PSMA3 5684
Affinity Capture-MS Homo sapiens
150 RPS19 6223
Co-fractionation Homo sapiens
151 CKAP5 9793
Affinity Capture-MS Homo sapiens
152 PSEN1 5663
Two-hybrid Homo sapiens
153 AGBL4  
Affinity Capture-MS Homo sapiens
154 NR4A1  
Affinity Capture-MS Homo sapiens
155 TDRD5  
Affinity Capture-MS Homo sapiens
156 KCND3 3752
Affinity Capture-Western Homo sapiens
157 Pank4  
Affinity Capture-MS Mus musculus
158 AHCYL1 10768
Co-fractionation Homo sapiens
159 IGHD  
Affinity Capture-MS Homo sapiens
160 Cct3 12462
Affinity Capture-MS Mus musculus
161 HELQ  
Affinity Capture-MS Homo sapiens
162 RC3H2  
Affinity Capture-MS Homo sapiens
163 TCP11L2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 PFDN2 5202
Affinity Capture-MS Homo sapiens
165 NELFCD 51497
Affinity Capture-MS Homo sapiens
166 HSPA4 3308
Co-fractionation Homo sapiens
167 EHMT2 10919
Affinity Capture-MS Homo sapiens
168 IQCB1  
Affinity Capture-MS Homo sapiens
169 PTH2R  
Affinity Capture-MS Homo sapiens
170 CST8  
Affinity Capture-MS Homo sapiens
171 ASPM 259266
Affinity Capture-MS Homo sapiens
172 TCP11L1 55346
Affinity Capture-MS Homo sapiens
173 CLASP1 23332
Affinity Capture-MS Homo sapiens
174 RICTOR 253260
Affinity Capture-MS Homo sapiens
175 CCP110  
Affinity Capture-MS Homo sapiens
176 TUBB4B 10383
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
177 EGFR 1956
Negative Genetic Homo sapiens
178 CCT3 7203
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
179 MYO19  
Affinity Capture-MS Homo sapiens
180 PRMT3 10196
Affinity Capture-MS Homo sapiens
181 FBXO6 26270
Affinity Capture-MS Homo sapiens
182 FUS 2521
Affinity Capture-MS Homo sapiens
183 ACE2 59272
Affinity Capture-MS Homo sapiens
184 MORF4L1  
Affinity Capture-MS Homo sapiens
185 RIPK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 RCN1 5954
Co-fractionation Homo sapiens
187 FN1 2335
Affinity Capture-MS Homo sapiens
188 TXNDC9 10190
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
189 AP2M1 1173
Affinity Capture-MS Homo sapiens
190 TOMM70A 9868
Affinity Capture-MS Homo sapiens
191 SPOP  
Affinity Capture-MS Homo sapiens
192 RANBP9 10048
Affinity Capture-Western Homo sapiens
193 MYCN  
Affinity Capture-MS Homo sapiens
194 CEP250 11190
Affinity Capture-MS Homo sapiens
195 SLAIN2  
Affinity Capture-MS Homo sapiens
196 LOXL4 84171
Affinity Capture-MS Homo sapiens
197 SERBP1 26135
Affinity Capture-MS Homo sapiens
198 LTV1  
Co-fractionation Homo sapiens
199 LGALS2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
200 TACC1 6867
Affinity Capture-MS Homo sapiens
201 MTOR 2475
Affinity Capture-MS Homo sapiens
202 CCT8 10694
Affinity Capture-MS Homo sapiens
203 INO80  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
204 LGALS7B 653499
Affinity Capture-MS Homo sapiens
205 PRDM13 59336
Affinity Capture-MS Homo sapiens
206 PRSS8 5652
Affinity Capture-MS Homo sapiens
207 ESRP2 80004
Affinity Capture-MS Homo sapiens
208 PRPF40A 55660
Co-fractionation Homo sapiens
209 STMN1 3925
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
210 RPL18 6141
Co-fractionation Homo sapiens
211 DDRGK1 65992
Affinity Capture-MS Homo sapiens
212 RNF2  
Affinity Capture-MS Homo sapiens
213 Kctd5  
Affinity Capture-MS Mus musculus
214 VDAC1 7416
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
215 HAT1 8520
Affinity Capture-MS Homo sapiens
216 SMYD1  
Affinity Capture-MS Homo sapiens
217 DLGAP5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 PFDN5 5204
Affinity Capture-MS Homo sapiens
219 ZMYM2  
Affinity Capture-MS Homo sapiens
220 ATXN7L3  
Affinity Capture-MS Homo sapiens
221 SFMBT1 51460
Affinity Capture-MS Homo sapiens
222 ZAP70 7535
Affinity Capture-Western Homo sapiens
223 PIGR 5284
Affinity Capture-MS Homo sapiens
224 NCAPG 64151
Affinity Capture-MS Homo sapiens
225 EIF3H 8667
Affinity Capture-MS Homo sapiens
226 TACC3  
Affinity Capture-MS Homo sapiens
227 TUBB2A 7280
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
228 SNCA 6622
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
229 EIF3F 8665
Affinity Capture-MS Homo sapiens
230 FGF11  
Affinity Capture-MS Homo sapiens
231 VBP1 7411
Affinity Capture-MS Homo sapiens
232 TUBGCP2 10844
Affinity Capture-MS Homo sapiens
233 RC3H1 149041
Affinity Capture-MS Homo sapiens
234 KIF14 9928
Affinity Capture-MS Homo sapiens
235 CCT7 10574
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
236 TSPYL5  
Affinity Capture-MS Homo sapiens
237 USP25  
Affinity Capture-MS Homo sapiens
238 FOLR1 2348
Affinity Capture-MS Homo sapiens
239 OPALIN  
Affinity Capture-MS Homo sapiens
240 TSPYL6  
Affinity Capture-MS Homo sapiens
241 INPPL1 3636
Affinity Capture-MS Homo sapiens
242 PDIA4 9601
Co-fractionation Homo sapiens
243 SLX1B  
Two-hybrid Homo sapiens
244 HDAC6 10013
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
245 CENPJ 55835
Affinity Capture-MS Homo sapiens
246 ISG15 9636
Reconstituted Complex Homo sapiens
247 LTA  
Affinity Capture-Western Homo sapiens
248 CDC37 11140
Affinity Capture-MS Homo sapiens
249 WNT4  
Affinity Capture-MS Homo sapiens
250 KIAA1429 25962
Affinity Capture-MS Homo sapiens
251 PFDN1 5201
Affinity Capture-MS Homo sapiens
252 KIF2A 3796
Affinity Capture-MS Homo sapiens
253 TUBB3 10381
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
254 C17orf89  
Affinity Capture-MS Homo sapiens
255 ZC2HC1A 51101
Affinity Capture-MS Homo sapiens
256 GBA 2629
Affinity Capture-MS Homo sapiens
257 TKT 7086
Affinity Capture-MS Homo sapiens
258 CLEC4C  
Affinity Capture-MS Homo sapiens
259 SLC6A3  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
260 ARMC6 93436
Affinity Capture-MS Homo sapiens
261 TUBB1 81027
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
262 TUBB4A 10382
Affinity Capture-MS Homo sapiens
263 SSBP1 6742
Co-fractionation Homo sapiens
264 POU2F1 5451
Affinity Capture-MS Homo sapiens
265 Ppp6r1  
Affinity Capture-MS Mus musculus
266 Tuba3a 22144
Affinity Capture-MS Mus musculus
267 SMYD3 64754
Affinity Capture-MS Homo sapiens
268 UFL1 23376
Affinity Capture-MS Homo sapiens
269 DNAJA2 10294
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
270 MAP1LC3A 84557
Affinity Capture-MS Homo sapiens
271 PPP1R12A 4659
Co-fractionation Homo sapiens
272 EZH2  
Affinity Capture-MS Homo sapiens
273 ERRFI1 54206
Affinity Capture-MS Homo sapiens
274 C16orf72 29035
Affinity Capture-MS Homo sapiens
275 STAG2 10735
Affinity Capture-MS Homo sapiens
276 TRIM31  
Affinity Capture-MS Homo sapiens
277 PINK1  
Affinity Capture-MS Homo sapiens
278 ORAI1 84876
Affinity Capture-MS Homo sapiens
279 XRCC6 2547
Proximity Label-MS Homo sapiens
280 SNW1 22938
Affinity Capture-MS Homo sapiens
281 KRAS 3845
Negative Genetic Homo sapiens
282 C9orf72  
Affinity Capture-MS Homo sapiens
283 MTCL1 23255
Reconstituted Complex Homo sapiens
284 PSMD1 5707
Co-fractionation Homo sapiens
285 PSMC4 5704
Co-fractionation Homo sapiens
286 CCT8L2  
Affinity Capture-MS Homo sapiens
287 PRMT1 3276
Affinity Capture-MS Homo sapiens
288 TBCB 1155
Affinity Capture-MS Homo sapiens
289 UBE2V2 7336
Affinity Capture-MS Homo sapiens
290 CUL4A 8451
Affinity Capture-MS Homo sapiens
291 HUWE1 10075
Affinity Capture-MS Homo sapiens
292 CDC5L 988
Affinity Capture-MS Homo sapiens
293 CAPN2 824
Co-fractionation Homo sapiens
View the network image/svg+xml
 Pathways in which TUBA1B is involved
PathwayEvidenceSource
Activation of AMPK downstream of NMDARs IEA Reactome
Activation of NMDA receptors and postsynaptic events IEA Reactome
Adaptive Immune System TAS Reactome
Aggrephagy TAS Reactome
Aggrephagy IEA Reactome
Antiviral mechanism by IFN-stimulated genes TAS Reactome
Asparagine N-linked glycosylation TAS Reactome
Assembly and cell surface presentation of NMDA receptors IEA Reactome
Autophagy TAS Reactome
Autophagy IEA Reactome
Axon guidance TAS Reactome
Axon guidance IEA Reactome
Carboxyterminal post-translational modifications of tubulin IEA Reactome
Carboxyterminal post-translational modifications of tubulin TAS Reactome
Cell Cycle TAS Reactome
Cell Cycle, Mitotic TAS Reactome
Cellular responses to stimuli TAS Reactome
Cellular responses to stress TAS Reactome
Chaperonin-mediated protein folding IEA Reactome
Cilium Assembly TAS Reactome
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding IEA Reactome
COPI-dependent Golgi-to-ER retrograde traffic TAS Reactome
COPI-independent Golgi-to-ER retrograde traffic TAS Reactome
COPI-mediated anterograde transport TAS Reactome
Cytokine Signaling in Immune system TAS Reactome
Developmental Biology TAS Reactome
Developmental Biology IEA Reactome
Disease TAS Reactome
EML4 and NUDC in mitotic spindle formation TAS Reactome
ER to Golgi Anterograde Transport TAS Reactome
Factors involved in megakaryocyte development and platelet production TAS Reactome
Formation of tubulin folding intermediates by CCT/TriC IEA Reactome
G2/M Transition TAS Reactome
Gap junction assembly IEA Reactome
Gap junction assembly TAS Reactome
Gap junction trafficking IEA Reactome
Gap junction trafficking TAS Reactome
Gap junction trafficking and regulation IEA Reactome
Gap junction trafficking and regulation TAS Reactome
Golgi-to-ER retrograde transport TAS Reactome
HCMV Early Events TAS Reactome
HCMV Infection TAS Reactome
Hedgehog 'off' state TAS Reactome
Hemostasis TAS Reactome
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand TAS Reactome
Immune System TAS Reactome
Infectious disease TAS Reactome
Interferon Signaling TAS Reactome
Intra-Golgi and retrograde Golgi-to-ER traffic TAS Reactome
Intraflagellar transport TAS Reactome
Kinesins TAS Reactome
L1CAM interactions TAS Reactome
L1CAM interactions IEA Reactome
M Phase TAS Reactome
Macroautophagy TAS Reactome
Macroautophagy IEA Reactome
Membrane Trafficking IEA Reactome
Membrane Trafficking TAS Reactome
Metabolism of proteins IEA Reactome
Metabolism of proteins TAS Reactome
MHC class II antigen presentation TAS Reactome
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane TAS Reactome
Mitotic Anaphase TAS Reactome
Mitotic G2-G2/M phases TAS Reactome
Mitotic Metaphase and Anaphase TAS Reactome
Mitotic Prometaphase TAS Reactome
Nervous system development TAS Reactome
Nervous system development IEA Reactome
Neuronal System IEA Reactome
Neurotransmitter receptors and postsynaptic signal transmission IEA Reactome
Nuclear Envelope (NE) Reassembly TAS Reactome
Organelle biogenesis and maintenance TAS Reactome
PKR-mediated signaling TAS Reactome
Post NMDA receptor activation events IEA Reactome
Post-chaperonin tubulin folding pathway IEA Reactome
Post-translational protein modification IEA Reactome
Post-translational protein modification TAS Reactome
Protein folding IEA Reactome
Recruitment of NuMA to mitotic centrosomes TAS Reactome
Recycling pathway of L1 TAS Reactome
Recycling pathway of L1 IEA Reactome
Resolution of Sister Chromatid Cohesion TAS Reactome
RHO GTPase cycle TAS Reactome
RHO GTPase Effectors TAS Reactome
RHO GTPases Activate Formins TAS Reactome
RHO GTPases activate IQGAPs TAS Reactome
RHOH GTPase cycle TAS Reactome
Sealing of the nuclear envelope (NE) by ESCRT-III TAS Reactome
Selective autophagy TAS Reactome
Selective autophagy IEA Reactome
Separation of Sister Chromatids TAS Reactome
Signal Transduction TAS Reactome
Signaling by Hedgehog TAS Reactome
Signaling by Rho GTPases TAS Reactome
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 TAS Reactome
The role of GTSE1 in G2/M progression after G2 checkpoint TAS Reactome
Translocation of SLC2A4 (GLUT4) to the plasma membrane IEA Reactome
Transmission across Chemical Synapses IEA Reactome
Transport of connexons to the plasma membrane TAS Reactome
Transport to the Golgi and subsequent modification TAS Reactome
Vesicle-mediated transport IEA Reactome
Vesicle-mediated transport TAS Reactome
Viral Infection Pathways TAS Reactome





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