Gene description for FANCM
Gene name	Fanconi anemia, complementation group M
Gene symbol	FANCM
Other names/aliases	FAAP250 KIAA1596
Species	Homo sapiens
Database cross references - FANCM
ExoCarta	ExoCarta_57697
Vesiclepedia	VP_57697
Entrez Gene	57697
HGNC	23168
MIM	609644
UniProt	Q8IYD8
FANCM identified in sEVs derived from the following tissue/cell type
Urine	21595033
Urine	21595033
Urine	21595033

Gene ontology annotations for FANCM

Molecular Function     four-way junction DNA binding GO:0000400 IBA     chromatin binding GO:0003682 IDA     DNA clamp loader activity GO:0003689 IEA     RNA helicase activity GO:0003724 IEA     nuclease activity GO:0004518 IEA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     four-way junction helicase activity GO:0009378 IBA     ATP hydrolysis activity GO:0016887 IEA     3'-5' DNA helicase activity GO:0043138 IBA     cohesin loader activity GO:0061775 IEA     chromatin extrusion motor activity GO:0140584 IEA     ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA     ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA Biological Process     resolution of meiotic recombination intermediates GO:0000712 IMP     chromatin remodeling GO:0006338 IEA     replication fork processing GO:0031297 IMP     DNA duplex unwinding GO:0032508 IEA     interstrand cross-link repair GO:0036297 IBA     interstrand cross-link repair GO:0036297 IDA     double-strand break repair via synthesis-dependent strand annealing GO:0045003 IBA     chromatin looping GO:0140588 IEA     positive regulation of protein monoubiquitination GO:1902527 IMP Subcellular Localization     chromatin GO:0000785 IDA     nucleoplasm GO:0005654 IDA     nucleoplasm GO:0005654 TAS     cytosol GO:0005829 TAS     Fanconi anaemia nuclear complex GO:0043240 IDA     FANCM-MHF complex GO:0071821 IDA     FANCM-MHF complex GO:0071821 IPI