Gene description for BLM
Gene name	Bloom syndrome, RecQ helicase-like
Gene symbol	BLM
Other names/aliases	BS RECQ2 RECQL2 RECQL3
Species	Homo sapiens
Database cross references - BLM
ExoCarta	ExoCarta_641
Vesiclepedia	VP_641
Entrez Gene	641
HGNC	1058
MIM	604610
UniProt	P54132
BLM identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for BLM

Molecular Function     ATPase activity GO:0016887 IDA     ATP-dependent helicase activity GO:0008026 IDA     protein binding GO:0005515 IPI     helicase activity GO:0004386 IDA     single-stranded DNA binding GO:0003697 IDA     p53 binding GO:0002039 IPI     annealing helicase activity GO:0036310 IDA     ATP-dependent DNA helicase activity GO:0004003 IMP     ATP-dependent 3'-5' DNA helicase activity GO:0043140 IEA     four-way junction helicase activity GO:0009378 IDA     ATP binding GO:0005524 IDA     G-quadruplex DNA binding GO:0051880 IDA     bubble DNA binding GO:0000405 IDA Biological Process     protein oligomerization GO:0051259 IDA     regulation of binding GO:0051098 IEA     alpha-beta T cell differentiation GO:0046632 IEA     double-strand break repair via homologous recombination GO:0000724 NAS     DNA duplex unwinding GO:0032508 IMP     DNA recombination GO:0006310 NAS     DNA double-strand break processing GO:0000729 IDA     post-translational protein modification GO:0043687 TAS     negative regulation of mitotic recombination GO:0045950 IEA     mitotic G2 DNA damage checkpoint GO:0007095 IDA     replication fork protection GO:0048478 NAS     cellular response to hydroxyurea GO:0072711 IDA     positive regulation of alpha-beta T cell proliferation GO:0046641 IEA     telomere maintenance GO:0000723 IEA     cellular response to DNA damage stimulus GO:0006974 IMP     DNA strand renaturation GO:0000733 IDA     replication fork processing GO:0031297 IDA     DNA repair GO:0006281 NAS     negative regulation of thymocyte apoptotic process GO:0070244 IEA     cellular response to ionizing radiation GO:0071479 IDA     regulation of cyclin-dependent protein serine/threonine kinase activity GO:0000079 IMP     negative regulation of DNA recombination GO:0045910 IMP     cellular protein metabolic process GO:0044267 TAS     negative regulation of cell division GO:0051782 IMP     response to X-ray GO:0010165 IDA     positive regulation of transcription, DNA-templated GO:0045893 IDA     cellular response to camptothecin GO:0072757 IDA     protein sumoylation GO:0016925 TAS Subcellular Localization     pronucleus GO:0045120 IEA     male germ cell nucleus GO:0001673 IEA     replication fork GO:0005657 IEA     lateral element GO:0000800 IDA     cytoplasm GO:0005737 IDA     chromosome, telomeric region GO:0000781 IDA     nuclear matrix GO:0016363 IDA     nucleolus GO:0005730 IDA     PML body GO:0016605 IDA     nucleoplasm GO:0005654 TAS     nuclear chromosome GO:0000228 IDA     nucleus GO:0005634 IDA