Experiment description of studies that identified TOPBP1 in exosomes

1 Experiment ID 226 MISEV standards ✔ EM EV Biophysical techniques ✔ GAPDH|CD9|FLOT1 EV Enriched markers ✔ LMNA|H2AFX|ATP5A1|TOMM20 EV Negative markers ✘ EV Particle analysis Identified molecule mRNA Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa) PubMed ID 26027894     Organism Homo sapiens Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar Journal name Journal of Extracellular Vesicles Publication year 2015 Sample Endothelial cells Sample name HMEC-1 Isolation/purification methods Differential ultracentrifugation Sucrose density gradient Flotation density 1.10 g/mL Molecules identified in the study miRNA Protein snoRNA lncRNA yRNA snRNA mRNA ncRNA mtRNA vtRNA scaRNA lincRNA Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa) Western blotting

Protein-protein interactions for TOPBP1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 E2F1 1869 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 2 RAD9A   Invivo Homo sapiens 3 PML 5371 Affinity Capture-Western Homo sapiens Affinity Capture-Western Homo sapiens 4 ZBTB17   Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 5 UBR5 51366 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Biochemical Activity Homo sapiens Affinity Capture-Western Homo sapiens 6 TOP2B 7155 Two-hybrid Homo sapiens View the network

Pathways in which TOPBP1 is involved

No pathways found