Gene description for RPA1
Gene name	replication protein A1, 70kDa
Gene symbol	RPA1
Other names/aliases	HSSB MST075 REPA1 RF-A RP-A RPA70
Species	Homo sapiens
Database cross references - RPA1
ExoCarta	ExoCarta_6117
Entrez Gene	6117
HGNC	10289
MIM	179835
UniProt	P27694
RPA1 identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Squamous carcinoma cells	20124223
Thymus	23844026

Gene ontology annotations for RPA1

Molecular Function     damaged DNA binding GO:0003684 IDA     metal ion binding GO:0046872 IEA     single-stranded DNA binding GO:0003697 IDA     chromatin binding GO:0003682 IEA     protein binding GO:0005515 IPI Biological Process     post-translational protein modification GO:0043687 TAS     nucleotide-excision repair, DNA damage removal GO:0000718 TAS     in utero embryonic development GO:0001701 IEA     DNA damage response, detection of DNA damage GO:0042769 TAS     DNA repair GO:0006281 TAS     DNA-dependent DNA replication GO:0006261 TAS     protein sumoylation GO:0016925 TAS     nucleotide-excision repair, DNA gap filling GO:0006297 TAS     mitotic cell cycle GO:0000278 TAS     base-excision repair GO:0006284 TAS     double-strand break repair via homologous recombination GO:0000724 TAS     error-free translesion synthesis GO:0070987 TAS     hemopoiesis GO:0030097 IEA     DNA strand elongation involved in DNA replication GO:0006271 TAS     meiotic nuclear division GO:0007126 IEA     telomere maintenance via semi-conservative replication GO:0032201 TAS     G1/S transition of mitotic cell cycle GO:0000082 TAS     cellular response to heat GO:0034605 TAS     DNA recombination GO:0006310 TAS     telomere maintenance via recombination GO:0000722 TAS     regulation of cellular response to heat GO:1900034 TAS     DNA recombinase assembly GO:0000730 TAS     telomere maintenance GO:0000723 TAS     mismatch repair GO:0006298 TAS     cellular protein metabolic process GO:0044267 TAS     double-strand break repair GO:0006302 TAS     nucleotide-excision repair GO:0006289 TAS     transcription-coupled nucleotide-excision repair GO:0006283 TAS     error-prone translesion synthesis GO:0042276 TAS     homeostasis of number of cells within a tissue GO:0048873 IEA     DNA replication GO:0006260 TAS     cell cycle checkpoint GO:0000075 IMP     translesion synthesis GO:0019985 TAS     positive regulation of cell proliferation GO:0008284 IEA Subcellular Localization     PML body GO:0016605 IDA     DNA replication factor A complex GO:0005662 IPI     nucleus GO:0005634 IDA     nucleoplasm GO:0005654 TAS     lateral element GO:0000800 IEA     male germ cell nucleus GO:0001673 IEA