Gene description for MAGOH
Gene name mago-nashi homolog, proliferation-associated (Drosophila)
Gene symbol MAGOH
Other names/aliases MAGOH1
MAGOHA
Species Homo sapiens
 Database cross references - MAGOH
ExoCarta ExoCarta_4116
Vesiclepedia VP_4116
Entrez Gene 4116
HGNC 6815
MIM 602603
UniProt P61326  
 MAGOH identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Mesenchymal stem cells 36408942    
 Gene ontology annotations for MAGOH
Molecular Function
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
Biological Process
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 IGI
    nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:0000184 IMP
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 IMP
    mRNA splicing, via spliceosome GO:0000398 IC
    mRNA export from nucleus GO:0006406 NAS
    regulation of translation GO:0006417 IEA
    RNA splicing GO:0008380 IBA
    regulation of mRNA processing GO:0050684 IDA
    regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay GO:2000622 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleus GO:0005634 NAS
    nucleoplasm GO:0005654 TAS
    cytosol GO:0005829 NAS
    nuclear speck GO:0016607 IEA
    exon-exon junction complex GO:0035145 IBA
    exon-exon junction complex GO:0035145 IDA
    exon-exon junction complex GO:0035145 IPI
    catalytic step 2 spliceosome GO:0071013 IBA
    catalytic step 2 spliceosome GO:0071013 IDA
    exon-exon junction subcomplex mago-y14 GO:1990501 IPI
 Experiment description of studies that identified MAGOH in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for MAGOH
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 HIST1H2BC 8347
Affinity Capture-MS Homo sapiens
3 RIT1 6016
Negative Genetic Homo sapiens
4 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
5 LUZP4  
Affinity Capture-MS Homo sapiens
6 RIOK1 83732
Affinity Capture-MS Homo sapiens
7 XIST  
Protein-RNA Homo sapiens
8 PHF6  
Affinity Capture-MS Homo sapiens
9 KRT1 3848
Affinity Capture-MS Homo sapiens
10 SMG6  
Affinity Capture-Western Homo sapiens
11 DOCK4 9732
Affinity Capture-MS Homo sapiens
12 RBM22 55696
Affinity Capture-MS Homo sapiens
13 Bbs5  
Two-hybrid Mus musculus
14 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
15 PPIE 10450
Affinity Capture-MS Homo sapiens
16 SRPK2 6733
Affinity Capture-MS Homo sapiens
17 FMR1 2332
Affinity Capture-MS Homo sapiens
18 RPL13A 23521
Affinity Capture-MS Homo sapiens
19 EPB41L3 23136
Affinity Capture-MS Homo sapiens
20 ACTC1 70
Affinity Capture-MS Homo sapiens
21 DBN1 1627
Affinity Capture-MS Homo sapiens
22 RPL10 6134
Affinity Capture-MS Homo sapiens
23 CHCHD1  
Proximity Label-MS Homo sapiens
24 HNRNPC 3183
Affinity Capture-MS Homo sapiens
25 CCDC9  
Affinity Capture-MS Homo sapiens
26 AQR 9716
Affinity Capture-MS Homo sapiens
27 SRSF2 6427
Affinity Capture-MS Homo sapiens
28 SRSF8 10929
Affinity Capture-MS Homo sapiens
29 RPL26L1 51121
Affinity Capture-MS Homo sapiens
30 ILF2 3608
Affinity Capture-MS Homo sapiens
31 DPPA4  
Two-hybrid Homo sapiens
32 CAPZB 832
Affinity Capture-MS Homo sapiens
33 TOP2A 7153
Affinity Capture-MS Homo sapiens
34 GSPT2 23708
Affinity Capture-MS Homo sapiens
35 RNPS1 10921
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 CRNKL1 51340
Affinity Capture-MS Homo sapiens
37 RPL7A 6130
Affinity Capture-MS Homo sapiens
38 CEP70  
Two-hybrid Homo sapiens
39 RBM3 5935
Affinity Capture-MS Homo sapiens
40 MCM2 4171
Affinity Capture-MS Homo sapiens
41 MOB2 81532
Affinity Capture-MS Homo sapiens
42 SPIN1  
Affinity Capture-MS Homo sapiens
43 SF3B1 23451
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 STK38L 23012
Affinity Capture-MS Homo sapiens
45 UPF3B 65109
Reconstituted Complex Homo sapiens
46 RPL24 6152
Affinity Capture-MS Homo sapiens
47 MAGOHB 55110
Cross-Linking-MS (XL-MS) Homo sapiens
48 CPSF7 79869
Two-hybrid Homo sapiens
49 SRRM2 23524
Affinity Capture-MS Homo sapiens
50 SNRPC 6631
Affinity Capture-MS Homo sapiens
51 RPS8 6202
Affinity Capture-MS Homo sapiens
52 FBL 2091
Affinity Capture-MS Homo sapiens
53 TFIP11  
Two-hybrid Homo sapiens
54 RPS9 6203
Affinity Capture-MS Homo sapiens
55 KRT5 3852
Affinity Capture-MS Homo sapiens
56 GSPT1 2935
Cross-Linking-MS (XL-MS) Homo sapiens
57 TRA2A 29896
Affinity Capture-MS Homo sapiens
58 SF3B3 23450
Affinity Capture-MS Homo sapiens
59 SARNP 84324
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 HIST1H2AA 221613
Affinity Capture-MS Homo sapiens
61 CHTOP  
Affinity Capture-MS Homo sapiens
62 LHX4  
Proximity Label-MS Homo sapiens
63 MECP2 4204
Affinity Capture-MS Homo sapiens
64 PFKFB3 5209
Affinity Capture-MS Homo sapiens
65 MYCN  
Affinity Capture-MS Homo sapiens
66 TSN 7247
Affinity Capture-MS Homo sapiens
67 RPS11 6205
Affinity Capture-MS Homo sapiens
68 RPL19 6143
Affinity Capture-MS Homo sapiens
69 RBM8A 9939
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
70 PPP1R16B  
Two-hybrid Homo sapiens
71 HSPA8 3312
Affinity Capture-MS Homo sapiens
72 GOLGA2 2801
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
73 CHMP4C 92421
Affinity Capture-MS Homo sapiens
74 LMNB1 4001
Affinity Capture-MS Homo sapiens
75 POLD1 5424
Affinity Capture-MS Homo sapiens
76 PRPF8 10594
Affinity Capture-MS Homo sapiens
77 CAPZA1 829
Affinity Capture-MS Homo sapiens
78 RPL4 6124
Affinity Capture-MS Homo sapiens
79 PGAM5 192111
Affinity Capture-MS Homo sapiens
80 MAP1B 4131
Affinity Capture-MS Homo sapiens
81 HIST1H2AG 8969
Cross-Linking-MS (XL-MS) Homo sapiens
82 Nudt21 68219
Two-hybrid Mus musculus
83 SRSF3 6428
Affinity Capture-MS Homo sapiens
84 EIF4B 1975
Affinity Capture-MS Homo sapiens
85 SPIN2A  
Affinity Capture-MS Homo sapiens
86 MAPRE1 22919
Affinity Capture-MS Homo sapiens
87 ACIN1 22985
Affinity Capture-MS Homo sapiens
88 SRSF6 6431
Affinity Capture-MS Homo sapiens
89 Mapre3  
Two-hybrid Mus musculus
90 SNRNP200 23020
Affinity Capture-MS Homo sapiens
91 SNRPB 6628
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 SNIP1  
Affinity Capture-MS Homo sapiens
93 CDH1 999
Negative Genetic Homo sapiens
94 SNRPD1 6632
Affinity Capture-MS Homo sapiens
95 MYH9 4627
Affinity Capture-MS Homo sapiens
96 RAN 5901
Affinity Capture-MS Homo sapiens
97 KRT9 3857
Affinity Capture-MS Homo sapiens
98 KRT14 3861
Affinity Capture-MS Homo sapiens
99 YWHAQ 10971
Affinity Capture-MS Homo sapiens
100 RPL27A 6157
Affinity Capture-MS Homo sapiens
101 ACTB 60
Affinity Capture-MS Homo sapiens
102 EZH2  
Affinity Capture-MS Homo sapiens
103 MYH10 4628
Affinity Capture-MS Homo sapiens
104 KRT2 3849
Affinity Capture-MS Homo sapiens
105 DDX17 10521
Affinity Capture-MS Homo sapiens
106 SNRPD3 6634
Affinity Capture-MS Homo sapiens
107 SON 6651
Affinity Capture-MS Homo sapiens
108 DDX39B 7919
Affinity Capture-MS Homo sapiens
109 ZC3H15 55854
Cross-Linking-MS (XL-MS) Homo sapiens
110 SRPK1 6732
Affinity Capture-MS Homo sapiens
111 SLC25A5 292
Affinity Capture-MS Homo sapiens
112 RBM10  
Affinity Capture-MS Homo sapiens
113 DPH2 1802
Two-hybrid Homo sapiens
114 PPM1B 5495
Affinity Capture-MS Homo sapiens
115 Rbm14  
Two-hybrid Mus musculus
116 HIST1H2AD 3013
Affinity Capture-MS Homo sapiens
117 SF3B2 10992
Affinity Capture-MS Homo sapiens
118 RBM39 9584
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 PRPF4B 8899
Affinity Capture-MS Homo sapiens
120 FANCD2  
Affinity Capture-MS Homo sapiens
121 C11orf57  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
122 SRSF7 6432
Affinity Capture-MS Homo sapiens
123 RPS2 6187
Affinity Capture-MS Homo sapiens
124 TDRD3  
Affinity Capture-Western Homo sapiens
125 R3HCC1L  
Affinity Capture-Western Homo sapiens
126 YBX1 4904
Affinity Capture-MS Homo sapiens
127 PNN 5411
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
128 SRSF4 6429
Affinity Capture-MS Homo sapiens
129 CAMSAP3  
Affinity Capture-MS Homo sapiens
130 PLRG1 5356
Affinity Capture-MS Homo sapiens
131 Mrps31  
Two-hybrid Mus musculus
132 SRSF1 6426
Affinity Capture-MS Homo sapiens
133 RPL21 6144
Affinity Capture-MS Homo sapiens
134 BLM 641
Affinity Capture-MS Homo sapiens
135 XAB2 56949
Affinity Capture-MS Homo sapiens
136 SRSF5 6430
Affinity Capture-MS Homo sapiens
137 RPL3 6122
Affinity Capture-MS Homo sapiens
138 MAGOH2P  
Affinity Capture-MS Homo sapiens
139 RPL7 6129
Affinity Capture-MS Homo sapiens
140 WIBG 84305
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
141 SUZ12  
Affinity Capture-MS Homo sapiens
142 HIST3H3 8290
Affinity Capture-MS Homo sapiens
143 SPTBN1 6711
Affinity Capture-MS Homo sapiens
144 NXF1 10482
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
145 SCYL2 55681
Affinity Capture-MS Homo sapiens
146 SF3A1 10291
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 YTHDC1  
Affinity Capture-MS Homo sapiens
148 EFTUD2 9343
Affinity Capture-MS Homo sapiens
149 PRMT5 10419
Affinity Capture-MS Homo sapiens
150 PTBP2  
Two-hybrid Homo sapiens
151 TADA2A  
Two-hybrid Homo sapiens
152 PRPF19 27339
Affinity Capture-MS Homo sapiens
153 MYC  
Affinity Capture-MS Homo sapiens
154 IPO13 9670
Reconstituted Complex Homo sapiens
155 JAK1 3716
Affinity Capture-MS Homo sapiens
156 BOLA2 552900
Affinity Capture-MS Homo sapiens
157 DNAJC9 23234
Proximity Label-MS Homo sapiens
158 TOP1 7150
Affinity Capture-MS Homo sapiens
159 HSPA1A 3303
Affinity Capture-MS Homo sapiens
160 CORO1A 11151
Two-hybrid Homo sapiens
161 MATR3 9782
Affinity Capture-MS Homo sapiens
162 SRSF10 10772
Affinity Capture-MS Homo sapiens
163 RPL18 6141
Affinity Capture-MS Homo sapiens
164 RNF2  
Affinity Capture-MS Homo sapiens
165 BMI1  
Affinity Capture-MS Homo sapiens
166 FYTTD1  
Affinity Capture-MS Homo sapiens
167 SCRN3 79634
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
168 HSPA9 3313
Affinity Capture-MS Homo sapiens
169 KRT19 3880
Affinity Capture-MS Homo sapiens
170 RPL26 6154
Affinity Capture-MS Homo sapiens
171 RBM33  
Affinity Capture-MS Homo sapiens
172 RPL15 6138
Affinity Capture-MS Homo sapiens
173 SNRPD2 6633
Affinity Capture-MS Homo sapiens
174 EEF1A1 1915
Affinity Capture-MS Homo sapiens
175 RPL13 6137
Affinity Capture-MS Homo sapiens
176 DHX15 1665
Affinity Capture-MS Homo sapiens
177 SNW1 22938
Affinity Capture-MS Homo sapiens
178 SRRM1 10250
Affinity Capture-MS Homo sapiens
179 FASN 2194
Affinity Capture-MS Homo sapiens
180 SPTAN1 6709
Affinity Capture-MS Homo sapiens
181 HNRNPH2 3188
Affinity Capture-MS Homo sapiens
182 BCAS2 10286
Affinity Capture-MS Homo sapiens
183 RPS3 6188
Affinity Capture-MS Homo sapiens
184 ILF3 3609
Affinity Capture-MS Homo sapiens
185 WDR77 79084
Affinity Capture-MS Homo sapiens
186 CPSF6 11052
Affinity Capture-MS Homo sapiens
187 RPL6 6128
Affinity Capture-MS Homo sapiens
188 POTEJ 653781
Affinity Capture-MS Homo sapiens
189 ERH 2079
Affinity Capture-MS Homo sapiens
190 VIM 7431
Affinity Capture-MS Homo sapiens
191 FXR1 8087
Two-hybrid Homo sapiens
192 SRSF9 8683
Affinity Capture-MS Homo sapiens
193 KRT10 3858
Affinity Capture-MS Homo sapiens
194 SAP18 10284
Affinity Capture-MS Homo sapiens
195 SRSF12  
Affinity Capture-MS Homo sapiens
196 SNRPA 6626
Affinity Capture-MS Homo sapiens
197 RBMX 27316
Affinity Capture-MS Homo sapiens
198 HNRNPM 4670
Affinity Capture-MS Homo sapiens
199 CLNS1A 1207
Affinity Capture-MS Homo sapiens
200 THRAP3 9967
Affinity Capture-MS Homo sapiens
201 CDC40  
Affinity Capture-MS Homo sapiens
202 DFFB  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
203 EIF4A3 9775
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
204 TRA2B 6434
Affinity Capture-MS Homo sapiens
205 CWC15  
Affinity Capture-MS Homo sapiens
206 HNRNPK 3190
Affinity Capture-MS Homo sapiens
207 STK38 11329
Affinity Capture-MS Homo sapiens
208 UBB 7314
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
209 SNRNP40 9410
Affinity Capture-MS Homo sapiens
210 E2F4  
Affinity Capture-MS Homo sapiens
211 RPS24 6229
Affinity Capture-MS Homo sapiens
212 ALYREF 10189
Affinity Capture-MS Homo sapiens
213 HNRNPL 3191
Affinity Capture-MS Homo sapiens
214 SNRNP70 6625
Affinity Capture-MS Homo sapiens
215 RTCB 51493
Affinity Capture-MS Homo sapiens
216 YBX3 8531
Affinity Capture-MS Homo sapiens
217 UPF1 5976
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
218 PRDX1 5052
Affinity Capture-MS Homo sapiens
219 RPS6