Gene description for BCAS2
Gene name breast carcinoma amplified sequence 2
Gene symbol BCAS2
Other names/aliases DAM1
SPF27
Snt309
Species Homo sapiens
 Database cross references - BCAS2
ExoCarta ExoCarta_10286
Entrez Gene 10286
HGNC 975
MIM 605783
UniProt O75934  
 BCAS2 identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for BCAS2
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    RNA splicing GO:0008380 TAS
    gene expression GO:0010467 TAS
    RNA splicing, via transesterification reactions GO:0000375 TAS
    mRNA splicing, via spliceosome GO:0000398 TAS
Subcellular Localization
    cell junction GO:0030054 IDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 TAS
    nucleolus GO:0005730 IEA
    spliceosomal complex GO:0005681 IDA
    DNA replication factor A complex GO:0005662 IDA
 Experiment description of studies that identified BCAS2 in exosomes
1
Experiment ID 217
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101
EV Cytosolic markers
✔
CD81|CD9|CD63
EV Membrane markers
✘ EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for BCAS2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PLRG1 5356
Affinity Capture-MS Homo sapiens
2 BLK 640
Invitro Homo sapiens
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which BCAS2 is involved
PathwayEvidenceSource
mRNA Splicing - Major Pathway TAS Reactome





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