Experiment description of studies that identified DISC1 in exosomes

1 Experiment ID 224 MISEV standards ✔ EM|AFM EV Biophysical techniques ✔ Alix|TSG101|CD63|CD81 EV Enriched markers ✔ GOLGA2 EV Negative markers ✘ EV Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 25944692     Organism Homo sapiens Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S Journal name Oncotarget Publication year 2015 Sample Neuroblastoma cells Sample name SH-SY5Y Isolation/purification methods Differential centrifugation Ultracentrifugation OptiPrep density gradient Flotation density 1.10 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry Western blotting

Protein-protein interactions for DISC1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 ATF5   Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 2 EIF3A 8661 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 3 FEZ1   Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 4 COL4A1 1282 Two-hybrid Homo sapiens 5 ITSN1 6453 Two-hybrid Homo sapiens 6 Cep63   Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 7 TRAF3IP1 26146 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 8 ATF7IP 55729 Two-hybrid Homo sapiens 9 SPTBN4 57731 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 10 KCNQ5   Two-hybrid Homo sapiens 11 SYNE1 23345 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 12 MYO1A 4640 Two-hybrid Homo sapiens 13 C11orf13   Two-hybrid Homo sapiens 14 KIAA1377   Two-hybrid Homo sapiens 15 ATF4   Two-hybrid Homo sapiens 16 RANBP9 10048 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 17 FLJ39502   Two-hybrid Homo sapiens 18 CIT 11113 Two-hybrid Homo sapiens 19 NDEL1 81565 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens 20 ACTN2 88 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 21 MAP1A 4130 Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens 22 YWHAG 7532 Two-hybrid Homo sapiens 23 EIF3H 8667 Two-hybrid Homo sapiens View the network

Pathways in which DISC1 is involved

No pathways found