Gene description for ASB3
Gene name ankyrin repeat and SOCS box containing 3
Gene symbol ASB3
Other names/aliases ASB-3
Species Homo sapiens
 Database cross references - ASB3
ExoCarta ExoCarta_51130
Vesiclepedia VP_51130
Entrez Gene 51130
HGNC 16013
MIM 605760
UniProt Q9Y575  
 ASB3 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for ASB3
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    protein ubiquitination GO:0016567 IEA
    intracellular signal transduction GO:0035556 IEA
Subcellular Localization
    cytosol GO:0005829 TAS
 Experiment description of studies that identified ASB3 in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ASB3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 PPP1R12B 4660
Affinity Capture-MS Homo sapiens
2 BCLAF1 9774
Affinity Capture-MS Homo sapiens
3 SAMD11  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 DISC1 27185
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 ENKD1  
Two-hybrid Homo sapiens
6 ENTHD2  
Two-hybrid Homo sapiens
7 AGL 178
Affinity Capture-MS Homo sapiens
8 SLC4A1AP  
Affinity Capture-MS Homo sapiens
9 ARIH2 10425
Affinity Capture-MS Homo sapiens
10 MFAP5  
Affinity Capture-MS Homo sapiens
11 ARHGAP32  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 ZNHIT6 54680
Affinity Capture-MS Homo sapiens
13 TNFRSF1B  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
14 TCEB1 6921
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
15 TNNI3K  
Affinity Capture-MS Homo sapiens
16 LARP4B 23185
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 CLASP2 23122
Affinity Capture-MS Homo sapiens
18 ATP5F1 515
Affinity Capture-MS Homo sapiens
19 ATXN2 6311
Affinity Capture-MS Homo sapiens
20 ERH 2079
Affinity Capture-MS Homo sapiens
21 AES 166
Two-hybrid Homo sapiens
22 LCOR 84458
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
23 RICTOR 253260
Affinity Capture-MS Homo sapiens
24 EPB41L3 23136
Affinity Capture-MS Homo sapiens
25 CUL5 8065
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 ASB6 140459
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
27 TROAP  
Affinity Capture-MS Homo sapiens
28 PRMT6  
Two-hybrid Homo sapiens
29 ZAP70 7535
Two-hybrid Homo sapiens
30 THRAP3 9967
Affinity Capture-MS Homo sapiens
31 RBX1 9978
Affinity Capture-MS Homo sapiens
32 ZNF318 24149
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
34 TOP2B 7155
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 PGAM5 192111
Affinity Capture-MS Homo sapiens
36 HSP90AA1 3320
Affinity Capture-Luminescence Homo sapiens
37 S100A9 6280
Affinity Capture-MS Homo sapiens
38 SALL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 GON4L  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 NONO 4841
Affinity Capture-MS Homo sapiens
41 RNF7  
Affinity Capture-MS Homo sapiens
42 SFPQ 6421
Affinity Capture-MS Homo sapiens
43 SATB2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 RPS27 6232
Affinity Capture-MS Homo sapiens
45 EIF4ENIF1 56478
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 TOP2A 7153
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 HIF1AN 55662
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
48 FAM110D  
Affinity Capture-MS Homo sapiens
49 RPL38 6169
Affinity Capture-MS Homo sapiens
50 DCUN1D1 54165
Affinity Capture-MS Homo sapiens
51 GPS1 2873
Affinity Capture-MS Homo sapiens
52 KATNA1 11104
Affinity Capture-MS Homo sapiens
53 CRACR2A  
Two-hybrid Homo sapiens
54 DENND4A 10260
Affinity Capture-MS Homo sapiens
55 PRDX6 9588
Affinity Capture-MS Homo sapiens
56 ZBTB46  
Affinity Capture-MS Homo sapiens
57 ERF  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 S100A8 6279
Affinity Capture-MS Homo sapiens
59 DNPEP 23549
Affinity Capture-MS Homo sapiens
60 SPANXN4  
Affinity Capture-MS Homo sapiens
61 TCEB2 6923
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 RCN2 5955
Affinity Capture-MS Homo sapiens
63 ATP5C1 509
Affinity Capture-MS Homo sapiens
64 STK19  
Affinity Capture-MS Homo sapiens
65 KIAA1671  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 FOXP4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 SRP14 6727
Affinity Capture-MS Homo sapiens
68 ZSWIM8 23053
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 KDM1A 23028
Two-hybrid Homo sapiens
70 USP54 159195
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
71 KATNB1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 SLC25A5 292
Affinity Capture-MS Homo sapiens
73 GSE1 23199
Affinity Capture-MS Homo sapiens
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