Gene description for ASB3
Gene name ankyrin repeat and SOCS box containing 3
Gene symbol ASB3
Other names/aliases ASB-3
Species Homo sapiens
 Database cross references - ASB3
ExoCarta ExoCarta_51130
Vesiclepedia VP_51130
Entrez Gene 51130
HGNC 16013
MIM 605760
UniProt Q9Y575  
 ASB3 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for ASB3
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    protein ubiquitination GO:0016567 IEA
    intracellular signal transduction GO:0035556 IEA
Subcellular Localization
    intracellular GO:0005622 IEA
 Experiment description of studies that identified ASB3 in exosomes
1
Experiment ID 488
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
EV Enriched markers
✔
CANX
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ.
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for ASB3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CUL5 8065
Affinity Capture-MS Homo sapiens
2 S100A9 6280
Affinity Capture-MS Homo sapiens
3 S100A8 6279
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ASB3 is involved
PathwayEvidenceSource
Antigen processing: Ubiquitination & Proteasome degradation TAS Reactome





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