Experiment description of studies that identified LCOR in exosomes

1 Experiment ID 237 MISEV standards ✔ EM Biophysical techniques ✔ TSG101|Alix|HSC70|GAPDH Enriched markers ✔ HSP90B1 Negative markers ✔ qNano Particle analysis Identified molecule mRNA Identification method RNA Sequencing PubMed ID 26054723     Organism Homo sapiens Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N" Journal name Carcinogenesis Publication year 2015 Sample Hepatocytes Sample name MIHA Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein RNA Methods used in the study Western blotting Mass spectrometry RNA Sequencing

Protein-protein interactions for LCOR

Protein Interactor ExoCarta ID Identification method PubMed Species 1 MAPK14 1432 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 HIST2H2BE 8349 Affinity Capture-MS Homo sapiens 3 Esrrb   Affinity Capture-MS Mus musculus 4 PHF1   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 AEBP2   Affinity Capture-MS Homo sapiens 6 HDAC4   Reconstituted Complex Homo sapiens 7 ASB3 51130 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 8 VDR   Reconstituted Complex Homo sapiens 9 ASF1A 25842 Proximity Label-MS Homo sapiens 10 CEP70   Two-hybrid Homo sapiens 11 RORB   Two-hybrid Homo sapiens 12 SLC25A6 293 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 13 USP43   Affinity Capture-MS Homo sapiens 14 RBPJ 3516 Affinity Capture-MS Homo sapiens 15 UBR7   Affinity Capture-MS Homo sapiens 16 SAMHD1 25939 Affinity Capture-MS Homo sapiens 17 Orc2   Affinity Capture-MS Mus musculus 18 CTBP2 1488 Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 19 Kifc1   Affinity Capture-MS Mus musculus 20 HDAC6 10013 Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens Reconstituted Complex Homo sapiens 21 KLHDC3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 22 Sacm1l 83493 Affinity Capture-MS Mus musculus 23 KPNB1 3837 Affinity Capture-MS Homo sapiens 24 HMGA1 3159 Affinity Capture-MS Homo sapiens 25 C10orf12   Affinity Capture-MS Homo sapiens 26 HMGN5 79366 Affinity Capture-MS Homo sapiens 27 NUMA1 4926 Affinity Capture-MS Homo sapiens 28 HIST1H4A 8359 Affinity Capture-MS Homo sapiens 29 CNOT2   Affinity Capture-MS Homo sapiens 30 BRD2   Affinity Capture-MS Homo sapiens 31 B4galt1   Affinity Capture-MS Mus musculus 32 Csde1 229663 Affinity Capture-MS Mus musculus 33 HDAC1 3065 Reconstituted Complex Homo sapiens 34 CTBP1 1487 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Proximity Label-MS Homo sapiens Affinity Capture-MS Homo sapiens 35 C17orf96   Affinity Capture-MS Homo sapiens 36 EZH1   Affinity Capture-MS Homo sapiens 37 Ppp4c 56420 Affinity Capture-MS Mus musculus 38 SUZ12   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 ESR1   Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens FRET Homo sapiens Reconstituted Complex Homo sapiens 40 GOLGA2 2801 Two-hybrid Homo sapiens 41 LRPAP1 4043 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 42 LRP1 4035 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 43 CBX3 11335 Proximity Label-MS Homo sapiens 44 PHF19   Affinity Capture-MS Homo sapiens 45 HDAC3 8841 Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 46 NDE1 54820 Affinity Capture-MS Homo sapiens 47 LRWD1   Affinity Capture-MS Homo sapiens 48 EZH2   Affinity Capture-MS Homo sapiens 49 MTF2   Affinity Capture-MS Homo sapiens 50 POGZ 23126 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 51 Kif4   Affinity Capture-MS Mus musculus 52 Chmp3   Affinity Capture-MS Mus musculus 53 Cdc37 12539 Affinity Capture-MS Mus musculus 54 JARID2   Affinity Capture-MS Homo sapiens 55 USP7 7874 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 56 EED   Affinity Capture-MS Homo sapiens 57 KLF6   Affinity Capture-Western Homo sapiens Two-hybrid Homo sapiens Affinity Capture-Western Homo sapiens Reconstituted Complex Homo sapiens 58 AR 367 Two-hybrid Homo sapiens Reconstituted Complex Homo sapiens 59 Prmt6   Affinity Capture-MS Mus musculus 60 BIRC7   Two-hybrid Homo sapiens 61 RAB4B 53916 Affinity Capture-MS Homo sapiens 62 NUCKS1 64710 Affinity Capture-MS Homo sapiens 63 Bub1   Affinity Capture-MS Mus musculus 64 BCL7B   Affinity Capture-MS Homo sapiens 65 ZYG11B   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 66 ZNF516 9658 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 67 CEBPA   Proximity Label-MS Homo sapiens 68 Tipin   Affinity Capture-MS Mus musculus 69 Tpx2   Affinity Capture-MS Mus musculus 70 RBBP4 5928 Affinity Capture-MS Homo sapiens 71 Rtfdc1   Affinity Capture-MS Mus musculus 72 TRAF1 7185 Two-hybrid Homo sapiens View the network

Pathways in which LCOR is involved

No pathways found