Gene description for ZNHIT6
Gene name zinc finger, HIT-type containing 6
Gene symbol ZNHIT6
Other names/aliases BCD1
C1orf181
NY-BR-75
Species Homo sapiens
 Database cross references - ZNHIT6
ExoCarta ExoCarta_54680
Vesiclepedia VP_54680
Entrez Gene 54680
HGNC 26089
UniProt Q9NWK9  
 ZNHIT6 identified in sEVs derived from the following tissue/cell type
Urine 19056867    
 Gene ontology annotations for ZNHIT6
Molecular Function
    TFIID-class transcription factor complex binding GO:0001094 IPI
    protein binding GO:0005515 IPI
    enzyme binding GO:0019899 IPI
    identical protein binding GO:0042802 IPI
    metal ion binding GO:0046872 IEA
    ATPase binding GO:0051117 IPI
Biological Process
    maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0000463 IBA
    box C/D snoRNP assembly GO:0000492 IBA
    box C/D snoRNP assembly GO:0000492 IMP
    snoRNA localization GO:0048254 IBA
    snoRNA localization GO:0048254 IMP
    protein complex oligomerization GO:0051259 IMP
Subcellular Localization
    nucleus GO:0005634 IBA
    extracellular exosome GO:0070062 HDA
    pre-snoRNP complex GO:0070761 IBA
    pre-snoRNP complex GO:0070761 IDA
 Experiment description of studies that identified ZNHIT6 in sEVs
1
Experiment ID 63
MISEV standards
Biophysical techniques
AQP2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for ZNHIT6
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBXN6 80700
Affinity Capture-MS Homo sapiens
2 LY86  
Affinity Capture-MS Homo sapiens
3 KPNA1 3836
Affinity Capture-MS Homo sapiens
4 FTL 2512
Affinity Capture-MS Homo sapiens
5 VWCE  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 IL17RA 23765
Affinity Capture-MS Homo sapiens
7 ASB3 51130
Affinity Capture-MS Homo sapiens
8 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
9 IL13RA2 3598
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
10 TUBB 203068
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 ZNHIT6 54680
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
12 NOP58 51602
Affinity Capture-MS Homo sapiens
13 PRKY  
Affinity Capture-MS Homo sapiens
14 PCDH20  
Affinity Capture-MS Homo sapiens
15 Ruvbl1 56505
Affinity Capture-MS Mus musculus
16 CIB2  
Affinity Capture-MS Homo sapiens
17 PCDHGA5  
Affinity Capture-MS Homo sapiens
18 LIPH 200879
Affinity Capture-MS Homo sapiens
19 KCNE3  
Affinity Capture-MS Homo sapiens
20 RUVBL2 10856
Affinity Capture-MS Homo sapiens
21 GDI1 2664
Affinity Capture-MS Homo sapiens
22 TRIM52  
Affinity Capture-MS Homo sapiens
23 FAM96A  
Affinity Capture-MS Homo sapiens
24 RAD51B  
Affinity Capture-MS Homo sapiens
25 BRD8 10902
Affinity Capture-MS Homo sapiens
26 CCT8L2  
Affinity Capture-MS Homo sapiens
27 CUL3 8452
Affinity Capture-MS Homo sapiens
28 TUBB4B 10383
Affinity Capture-MS Homo sapiens
29 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
30 METTL21B  
Affinity Capture-MS Homo sapiens
31 SIRT1  
Affinity Capture-MS Homo sapiens
32 HNRNPCL2 440563
Affinity Capture-MS Homo sapiens
33 ZCCHC7  
Affinity Capture-MS Homo sapiens
34 PRPS2 5634
Affinity Capture-MS Homo sapiens
35 AHCYL2 23382
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 SKAP1 8631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
37 PROZ 8858
Affinity Capture-MS Homo sapiens
38 GCH1  
Affinity Capture-MS Homo sapiens
39 RUVBL1 8607
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
40 CDC16 8881
Affinity Capture-MS Homo sapiens
41 PIPSL 266971
Affinity Capture-MS Homo sapiens
42 S100P 6286
Affinity Capture-MS Homo sapiens
43 NAA11 84779
Affinity Capture-MS Homo sapiens
44 FAM46A  
Affinity Capture-MS Homo sapiens
45 NUFIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
46 CARD8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 LGI1  
Affinity Capture-MS Homo sapiens
48 SMAD2 4087
Two-hybrid Homo sapiens
49 TGM5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
50 PTGES3 10728
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 KRAS 3845
Synthetic Lethality Homo sapiens
52 F9 2158
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 FBLN5 10516
Affinity Capture-MS Homo sapiens
54 PDE7B  
Affinity Capture-MS Homo sapiens
55 PPP4R1L  
Affinity Capture-MS Homo sapiens
56 C9orf72  
Affinity Capture-MS Homo sapiens
57 ZNHIT3  
Affinity Capture-Western Homo sapiens
58 Nhp2l1 20826
Affinity Capture-MS Mus musculus
59 ANKRD9  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which ZNHIT6 is involved
No pathways found





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