Gene description for THRAP3
Gene name thyroid hormone receptor associated protein 3
Gene symbol THRAP3
Other names/aliases TRAP150
Species Homo sapiens
 Database cross references - THRAP3
ExoCarta ExoCarta_9967
Vesiclepedia VP_9967
Entrez Gene 9967
HGNC 22964
MIM 603809
UniProt Q9Y2W1  
 THRAP3 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Hepatocytes 26054723    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
T lymphocytes 34108659    
 Gene ontology annotations for THRAP3
Molecular Function
    RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 ISS
    DNA binding GO:0003677 IBA
    transcription coregulator activity GO:0003712 IBA
    transcription coregulator activity GO:0003712 IDA
    transcription coactivator activity GO:0003713 IDA
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    nuclear receptor coactivator activity GO:0030374 NAS
    nuclear vitamin D receptor binding GO:0042809 NAS
    nuclear thyroid hormone receptor binding GO:0046966 IDA
    phosphoprotein binding GO:0051219 IDA
Biological Process
    regulation of alternative mRNA splicing, via spliceosome GO:0000381 IMP
    nuclear-transcribed mRNA catabolic process GO:0000956 IDA
    mRNA processing GO:0006397 IEA
    circadian rhythm GO:0007623 IEA
    RNA splicing GO:0008380 IEA
    positive regulation of circadian rhythm GO:0042753 IMP
    positive regulation of DNA-templated transcription GO:0045893 IDA
    positive regulation of transcription by RNA polymerase II GO:0045944 IBA
    positive regulation of transcription by RNA polymerase II GO:0045944 IDA
    positive regulation of mRNA splicing, via spliceosome GO:0048026 IMP
    mRNA stabilization GO:0048255 IMP
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    mediator complex GO:0016592 IBA
    mediator complex GO:0016592 IDA
    nuclear speck GO:0016607 IDA
    exon-exon junction complex GO:0035145 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified THRAP3 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
7
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
18
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
20
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
21
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
26
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
27
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
28
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
30
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
31
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
32
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
33
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
 Protein-protein interactions for THRAP3
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UBE2H 7328
Affinity Capture-MS Homo sapiens
2 Mdm2  
Affinity Capture-MS Mus musculus
3 CAMKV 79012
Affinity Capture-MS Homo sapiens
4 CPSF6 11052
Affinity Capture-MS Homo sapiens
5 LUZP4  
Affinity Capture-MS Homo sapiens
6 CLEC3B 7123
Affinity Capture-MS Homo sapiens
7 HDAC4  
Affinity Capture-MS Homo sapiens
8 RNF40 9810
Affinity Capture-MS Homo sapiens
9 CBX1 10951
Affinity Capture-MS Homo sapiens
10 KPNA3 3839
Co-fractionation Homo sapiens
11 LGR4 55366
Affinity Capture-MS Homo sapiens
12 PAXIP1  
Affinity Capture-MS Homo sapiens
13 POT1  
Affinity Capture-MS Homo sapiens
14 ANLN 54443
Affinity Capture-MS Homo sapiens
15 WWP1 11059
Affinity Capture-MS Homo sapiens
16 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
17 DLST 1743
Affinity Capture-MS Homo sapiens
18 SRPK2 6733
Affinity Capture-MS Homo sapiens
19 PUF60 22827
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
20 BTF3 689
Affinity Capture-MS Homo sapiens
21 KPNB1 3837
Cross-Linking-MS (XL-MS) Homo sapiens
22 ALB 213
Affinity Capture-MS Homo sapiens
23 ACTC1 70
Proximity Label-MS Homo sapiens
24 DHX8 1659
Proximity Label-MS Homo sapiens
25 Aif1l  
Affinity Capture-MS Mus musculus
26 RPS19 6223
Co-fractionation Homo sapiens
27 Ndc80  
Affinity Capture-MS Mus musculus
28 MCM5 4174
Affinity Capture-MS Homo sapiens
29 HNRNPC 3183
Affinity Capture-MS Homo sapiens
30 CSNK2A1 1457
Biochemical Activity Homo sapiens
31 PRPF3  
Co-fractionation Homo sapiens
32 HNRNPCL1 343069
Affinity Capture-MS Homo sapiens
33 CAND1 55832
Affinity Capture-MS Homo sapiens
34 LRRC59 55379
Cross-Linking-MS (XL-MS) Homo sapiens
35 APBB1  
Reconstituted Complex Homo sapiens
36 PARK7 11315
Affinity Capture-MS Homo sapiens
37 ISG15 9636
Affinity Capture-MS Homo sapiens
38 SNRPD2 6633
Affinity Capture-MS Homo sapiens
39 SFPQ 6421
Co-fractionation Homo sapiens
40 GSK3A 2931
Affinity Capture-MS Homo sapiens
41 APEX1 328
Affinity Capture-MS Homo sapiens
42 PSIP1 11168
Co-fractionation Homo sapiens
43 DIMT1 27292
Affinity Capture-MS Homo sapiens
44 DDX23 9416
Proximity Label-MS Homo sapiens
45 DROSHA  
Affinity Capture-MS Homo sapiens
46 SNRNP70 6625
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 RNPS1 10921
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
48 RBM6 10180
Affinity Capture-MS Homo sapiens
49 SSRP1 6749
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
50 TGFB1 7040
Affinity Capture-MS Homo sapiens
51 KIF23 9493
Affinity Capture-MS Homo sapiens
52 SNRPF 6636
Affinity Capture-MS Homo sapiens
53 SPIN1  
Affinity Capture-MS Homo sapiens
54 SF3B1 23451
Affinity Capture-MS Homo sapiens
55 CHCHD2  
Affinity Capture-MS Homo sapiens
56 HIST2H3A 333932
Cross-Linking-MS (XL-MS) Homo sapiens
57 FBXW7  
Affinity Capture-MS Homo sapiens
58 PRC1 9055
Affinity Capture-MS Homo sapiens
59 IQGAP1 8826
Co-fractionation Homo sapiens
60 CHCHD10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
61 MDC1  
Affinity Capture-MS Homo sapiens
62 SNRPC 6631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 DDRGK1 65992
Affinity Capture-MS Homo sapiens
64 YWHAG 7532
Affinity Capture-MS Homo sapiens
65 OBSL1 23363
Affinity Capture-MS Homo sapiens
66 HMGA1 3159
Affinity Capture-MS Homo sapiens
67 MYCN  
Affinity Capture-MS Homo sapiens
68 SRSF3 6428
Affinity Capture-MS Homo sapiens
69 BMI1  
Affinity Capture-MS Homo sapiens
70 NELFE 7936
Affinity Capture-MS Homo sapiens
71 TNFRSF13B  
Affinity Capture-MS Homo sapiens
72 RC3H2  
Affinity Capture-MS Homo sapiens
73 MECP2 4204
Affinity Capture-MS Homo sapiens
74 NUDT12  
Affinity Capture-MS Homo sapiens
75 VDR  
Affinity Capture-MS Homo sapiens
76 RBM42  
Affinity Capture-MS Homo sapiens
77 PSAP 5660
Co-fractionation Homo sapiens
78 THOC1 9984
Affinity Capture-MS Homo sapiens
79 ADSS 159
Affinity Capture-MS Homo sapiens
80 NEDD4 4734
Reconstituted Complex Homo sapiens
81 SREK1 140890
Affinity Capture-MS Homo sapiens
82 SNIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 EEF1A1 1915
Co-fractionation Homo sapiens
84 RBM14 10432
Co-fractionation Homo sapiens
85 RBM8A 9939
Affinity Capture-MS Homo sapiens
86 KIF14 9928
Affinity Capture-MS Homo sapiens
87 PSME3 10197
Affinity Capture-MS Homo sapiens
88 MED1 5469
Co-purification Homo sapiens
89 H2AFZ 3015
Affinity Capture-MS Homo sapiens
90 PRPF6 24148
Co-fractionation Homo sapiens
91 SF3A2 8175
Affinity Capture-MS Homo sapiens
92 DLD 1738
Affinity Capture-MS Homo sapiens
93 FOXA1  
Affinity Capture-MS Homo sapiens
94 COX15 1355
Affinity Capture-MS Homo sapiens
95 DDX21 9188
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
96 MEN1 4221
Affinity Capture-MS Homo sapiens
97 USP11 8237
Affinity Capture-MS Homo sapiens
98 KIF20A 10112
Affinity Capture-MS Homo sapiens
99 MEPCE 56257
Affinity Capture-MS Homo sapiens
100 WHSC1 7468
Affinity Capture-MS Homo sapiens
101 MAP1B 4131
Co-fractionation Homo sapiens
102 PLK2  
Affinity Capture-MS Homo sapiens
103 SUPT5H 6829
Affinity Capture-MS Homo sapiens
104 SNRPA 6626
Affinity Capture-MS Homo sapiens
105 TRA2A 29896
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 GLE1 2733
Affinity Capture-MS Homo sapiens
107 ACIN1 22985
Co-fractionation Homo sapiens
108 SRSF6 6431
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
109 HIST1H3E 8353
Affinity Capture-MS Homo sapiens
110 SNRNP200 23020
Co-fractionation Homo sapiens
111 SNRPB 6628
Affinity Capture-MS Homo sapiens
112 DEK 7913
Co-fractionation Homo sapiens
113 MKRN2 23609
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
114 CHMP4B 128866
Affinity Capture-MS Homo sapiens
115 FOXL2  
Affinity Capture-MS Homo sapiens
116 BARD1 580
Affinity Capture-MS Homo sapiens
117 DDX5 1655
Co-fractionation Homo sapiens
118 NTRK1 4914
Affinity Capture-MS Homo sapiens
119 FOXK2  
Affinity Capture-MS Homo sapiens
120 ALKBH3  
Affinity Capture-MS Homo sapiens
121 RAD18  
Affinity Capture-MS Homo sapiens
122 DNAJA1 3301
Co-fractionation Homo sapiens
123 NCL 4691
Co-fractionation Homo sapiens
124 LUC7L2 51631
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
125 PCLO 27445
Cross-Linking-MS (XL-MS) Homo sapiens
126 SF3B6 51639
Co-fractionation Homo sapiens
127 RPA4  
Proximity Label-MS Homo sapiens
128 DHX40  
Proximity Label-MS Homo sapiens
129 DHX9 1660
Co-fractionation Homo sapiens
130 ZC3H14  
Affinity Capture-MS Homo sapiens
131 MAGOH 4116
Affinity Capture-MS Homo sapiens
132 SRSF4 6429
Affinity Capture-MS Homo sapiens
133 SRPK3  
Affinity Capture-MS Homo sapiens
134 DDX39B 7919
Affinity Capture-MS Homo sapiens
135 SDPR 8436
Co-fractionation Homo sapiens
136 H2AFY 9555
Co-fractionation Homo sapiens
137 PPM1G 5496
Co-fractionation Homo sapiens
138 CEBPA  
Protein-peptide Homo sapiens
139 Tipin  
Affinity Capture-MS Mus musculus
140 CYLD  
Affinity Capture-MS Homo sapiens
141 SRPK1 6732
Affinity Capture-MS Homo sapiens
142 ASB18  
Affinity Capture-MS Homo sapiens
143 AHCYL1 10768
Co-fractionation Homo sapiens
144 HMGB2 3148
Cross-Linking-MS (XL-MS) Homo sapiens
145 OGT 8473
Reconstituted Complex Homo sapiens
146 EEF1D 1936
Co-fractionation Homo sapiens
147 SNRPB2 6629
Affinity Capture-MS Homo sapiens
148 BCLAF1 9774
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
149 SRSF11 9295
Co-fractionation Homo sapiens
150 RBBP6 5930
Affinity Capture-MS Homo sapiens
151 DOK4 55715
Cross-Linking-MS (XL-MS) Homo sapiens
152 GAN 8139
Affinity Capture-MS Homo sapiens
153 SF3B2 10992
Co-fractionation Homo sapiens
154 ZBTB2 57621
Affinity Capture-MS Homo sapiens
155 RBM39 9584
Affinity Capture-MS Homo sapiens
156 PRPF4B 8899
Affinity Capture-MS Homo sapiens
157 HIST1H3A 8350
Cross-Linking-MS (XL-MS) Homo sapiens
158 FANCD2  
Affinity Capture-MS Homo sapiens
159 C11orf57  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 METTL14  
Affinity Capture-MS Homo sapiens
161 TRIM31  
Affinity Capture-MS Homo sapiens
162 U2AF2 11338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
163 CLK3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 XPO1 7514
Affinity Capture-MS Homo sapiens
165 LMNB1 4001
Affinity Capture-MS Homo sapiens
166 LXN 56925
Affinity Capture-MS Homo sapiens
167 ECT2 1894
Affinity Capture-MS Homo sapiens
168 PNN 5411
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
169 CD2BP2 10421
Affinity Capture-MS Homo sapiens
170 CTNNB1 1499
Affinity Capture-MS Homo sapiens
171 SRSF1 6426
Affinity Capture-MS Homo sapiens
172 CD40 958
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
173 PRMT8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
174 CTCF  
Co-fractionation Homo sapiens
175 CD9 928
Co-fractionation Homo sapiens
176 HMGB1 3146
Cross-Linking-MS (XL-MS) Homo sapiens
177 MAP9 79884
Cross-Linking-MS (XL-MS) Homo sapiens
178 FUS 2521
Affinity Capture-MS Homo sapiens
179 METTL3  
Affinity Capture-MS Homo sapiens
180 ASB3 51130
Affinity Capture-MS Homo sapiens
181 RBM33  
Affinity Capture-MS Homo sapiens
182 SUZ12  
Affinity Capture-MS Homo sapiens
183 SART1 9092
Co-fractionation Homo sapiens
184 SF3A1 10291
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
185 AKAP8  
Co-fractionation Homo sapiens
186 TNPO2 30000
Co-fractionation Homo sapiens
187 MKRN1 23608
Affinity Capture-MS Homo sapiens
188 RUNX1T1  
Affinity Capture-MS Homo sapiens
189 PCBP1 5093
Affinity Capture-MS Homo sapiens
190 MYC  
Affinity Capture-MS Homo sapiens
191 RPA3 6119
Proximity Label-MS Homo sapiens
192 YBX3 8531
Co-fractionation Homo sapiens
193 ARRDC3 57561
Affinity Capture-MS Homo sapiens
194 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
195 EEF1G 1937
Co-fractionation Homo sapiens
196 TOP1 7150
Affinity Capture-MS Homo sapiens
197 CSNK2B 1460
Affinity Capture-MS Homo sapiens
198 SART3 9733
Affinity Capture-MS Homo sapiens
199 HNF1B  
Affinity Capture-MS Homo sapiens
200 PARP1 142
Affinity Capture-Western Homo sapiens
201 RNF2  
Affinity Capture-MS Homo sapiens
202 SF3B3 23450
Co-fractionation Homo sapiens
203 VDAC1 7416
Affinity Capture-MS Homo sapiens
204 Erh  
Affinity Capture-MS Mus musculus
205 Mad2l1 56150
Affinity Capture-MS Mus musculus
206 NCSTN 23385
Co-fractionation Homo sapiens
207 C11orf58  
Co-fractionation Homo sapiens
208 SRSF8 10929
Affinity Capture-MS Homo sapiens
209 PHGDH 26227
Co-fractionation Homo sapiens
210 ECE1 1889
Cross-Linking-MS (XL-MS) Homo sapiens
211 AHSA1 10598
Affinity Capture-MS Homo sapiens
212 CORO2A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
213 TRIP6 7205
Affinity Capture-MS Homo sapiens
214 LLGL2 3993
Affinity Capture-MS Homo sapiens
215 GPALPP1  
Cross-Linking-MS (XL-MS) Homo sapiens
216 ARRB2 409
Affinity Capture-MS Homo sapiens
217 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
218 FBXW11  
Affinity Capture-MS Homo sapiens
219 TERF2  
Affinity Capture-MS Homo sapiens
220 SMN1 6606
Affinity Capture-MS Homo sapiens
221 H3F3A 3020
Affinity Capture-MS Homo sapiens
222 TP53 7157
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
223 CDK8 1024
Affinity Capture-MS Homo sapiens
224 WWOX 51741
Affinity Capture-MS Homo sapiens
225 APOBEC3D  
Affinity Capture-MS Homo sapiens
226 SNRPA1 6627
Co-fractionation Homo sapiens
227 PIN1 5300
Reconstituted Complex Homo sapiens
228 PHRF1  
Affinity Capture-MS Homo sapiens
229 PPHLN1  
Affinity Capture-MS Homo sapiens
230 MATN2 4147
Affinity Capture-MS Homo sapiens
231 SAP18 10284
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
232 PDHA1 5160
Affinity Capture-MS Homo sapiens
233 HNRNPM 4670
Co-fractionation Homo sapiens
234 SMURF1 57154
Affinity Capture-MS Homo sapiens
235 FAM208B 54906
Affinity Capture-MS Homo sapiens
236 MKRN3  
Affinity Capture-MS Homo sapiens
237 ERH 2079
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
238 EIF4A3 9775
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
239 RBMX 27316
Affinity Capture-MS Homo sapiens
240 S100A9 6280
Co-fractionation Homo sapiens
241 ESR1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
242 PDZD8 118987
Affinity Capture-MS Homo sapiens
243 UFL1 23376
Affinity Capture-MS Homo sapiens
244 COQ2  
Affinity Capture-MS Homo sapiens
245 IK 3550
Co-fractionation Homo sapiens
246 MED12  
Affinity Capture-MS Homo sapiens
247 API5 8539
Affinity Capture-MS Homo sapiens
248 EZH2  
Affinity Capture-MS Homo sapiens
249 AURKA 6790
Affinity Capture-MS Homo sapiens
250 GSPT2 23708
Affinity Capture-MS Homo sapiens
251 ARRB1 408
Affinity Capture-MS Homo sapiens
252 TRIP4 9325
Affinity Capture-MS Homo sapiens
253 SRSF7 6432
Affinity Capture-MS Homo sapiens
254 PINK1  
Affinity Capture-MS Homo sapiens
255 CLK2 1196
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
256 Cdc6 23834
Affinity Capture-MS Mus musculus
257 C1QBP 708
Affinity Capture-MS Homo sapiens
258 Slain1  
Affinity Capture-MS Mus musculus
259 CUL7 9820
Affinity Capture-MS Homo sapiens
260 KRAS 3845
Affinity Capture-MS Homo sapiens
261 HNRNPU 3192
Co-fractionation Homo sapiens
262 RC3H1 149041
Affinity Capture-MS Homo sapiens
263 IVNS1ABP  
Affinity Capture-MS Homo sapiens
264 Kif1c  
Affinity Capture-MS Mus musculus
265 PRMT1 3276
Affinity Capture-MS Homo sapiens
266 LUC7L 55692
Affinity Capture-MS Homo sapiens
267 Ube2i  
Two-hybrid Mus musculus
268 CASC3  
Co-fractionation Homo sapiens
269 PPIG 9360
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here