Gene description for WWP1
Gene name
WW domain containing E3 ubiquitin protein ligase 1
Gene symbol
WWP1
Other names/aliases
AIP5 Tiul1 hSDRP1
Species
Homo sapiens
Database cross references - WWP1
ExoCarta
ExoCarta_11059
Entrez Gene
11059
HGNC
17004
MIM
602307
UniProt
Q9H0M0
WWP1 identified in exosomes derived from the following tissue/cell type
Platelets
25332113
Platelets
25332113
Platelets
25332113
Gene ontology annotations for WWP1
Experiment description of studies that identified WWP1 in exosomes
1
Experiment ID
231
ISEV standards
✘
EV Biophysical techniques
✔
Alix
EV Cytosolic markers
✔
CD63|CD9
EV Membrane markers
✘
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 1
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein Lipids
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
232
ISEV standards
✘
EV Biophysical techniques
✘
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 2
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
233
ISEV standards
✘
EV Biophysical techniques
✘
EV Cytosolic markers
✘
EV Membrane markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
25332113
Organism
Homo sapiens
Experiment description
Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors
Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G.
Journal name
Transfusion
Publication year
2015
Sample
Platelets
Sample name
PL-Exs - Rep 3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Optiprep density gradient
Flotation density
1.12-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for WWP1
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
DIDO1
Two-hybrid
Homo sapiens
2
DAZAP2
Two-hybrid
Homo sapiens
3
KLF2
10365
Invivo
Homo sapiens
Invitro
Homo sapiens
Two-hybrid
Homo sapiens
4
WBP2
23558
Protein-peptide
Homo sapiens
5
EWSR1
2130
Two-hybrid
Homo sapiens
6
SMAD5
4090
Affinity Capture-MS
Homo sapiens
7
WBP1
Protein-peptide
Homo sapiens
8
CPSF6
11052
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
9
RNF11
26994
Affinity Capture-MS
Homo sapiens
10
ATN1
Two-hybrid
Homo sapiens
11
ZNF638
27332
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which WWP1 is involved