Gene description for SCRT1
Gene name scratch family zinc finger 1
Gene symbol SCRT1
Other names/aliases SCRT
ZNF898
Species Homo sapiens
 Database cross references - SCRT1
ExoCarta ExoCarta_83482
Entrez Gene 83482
HGNC 15950
MIM 605858
UniProt Q9BWW7  
 SCRT1 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for SCRT1
Molecular Function
    DNA binding GO:0003677 IEA
    metal ion binding GO:0046872 IEA
    sequence-specific DNA binding transcription factor activity GO:0003700 NAS
Biological Process
    regulation of neuron migration GO:2001222 IEA
    negative regulation of transcription from RNA polymerase II promoter GO:0000122 IEA
    transcription, DNA-templated GO:0006351 IEA
    regulation of transcription, DNA-templated GO:0006355 TAS
Subcellular Localization
    nucleus GO:0005634 IEA
 Experiment description of studies that identified SCRT1 in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for SCRT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SCRT1 is involved
No pathways found





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