Gene description for KLHDC10
Gene name kelch domain containing 10
Gene symbol KLHDC10
Other names/aliases slim
Species Homo sapiens
 Database cross references - KLHDC10
ExoCarta ExoCarta_23008
Entrez Gene 23008
HGNC 22194
MIM 615152
UniProt Q6PID8  
 KLHDC10 identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for KLHDC10
Molecular Function
    protein binding GO:0005515 IPI
Subcellular Localization
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified KLHDC10 in exosomes
1
Experiment ID 224
ISEV standards
EM|AFM
EV Biophysical techniques
Alix|TSG101
EV Cytosolic markers
CD63|CD81
EV Membrane markers
GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for KLHDC10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which KLHDC10 is involved
No pathways found





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