Gene description for C1QTNF1
Gene name C1q and tumor necrosis factor related protein 1
Gene symbol C1QTNF1
Other names/aliases CTRP1
GIP
ZSIG37
Species Homo sapiens
 Database cross references - C1QTNF1
ExoCarta ExoCarta_114897
Vesiclepedia VP_114897
Entrez Gene 114897
HGNC 14324
MIM 610365
UniProt Q9BXJ1  
 C1QTNF1 identified in exosomes derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for C1QTNF1
Molecular Function
    protein binding GO:0005515 IPI
    collagen binding GO:0005518 IDA
    identical protein binding GO:0042802 IEA
Biological Process
    positive regulation of cytosolic calcium ion concentration GO:0007204 IDA
    negative regulation of platelet activation GO:0010544 IDA
    positive regulation of gene expression GO:0010628 IDA
    regulation of glucose metabolic process GO:0010906 IEA
    positive regulation of MAPK cascade GO:0043410 IEA
    positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051897 IEA
    negative regulation of platelet aggregation GO:0090331 IDA
    positive regulation of aldosterone secretion GO:2000860 IDA
Subcellular Localization
    collagen trimer GO:0005581 IEA
    extracellular space GO:0005615 IBA
    extracellular space GO:0005615 IDA
    plasma membrane GO:0005886 IDA
 Experiment description of studies that identified C1QTNF1 in exosomes
1
Experiment ID 66
MISEV standards
IEM
Biophysical techniques
TSG101|Alix|CD63|CD81
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for C1QTNF1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 COL14A1 7373
Affinity Capture-MS Homo sapiens
2 UBL5 59286
Two-hybrid Homo sapiens
3 ZMYM4  
Affinity Capture-MS Homo sapiens
4 COLGALT2  
Affinity Capture-MS Homo sapiens
5 COLEC12 81035
Affinity Capture-MS Homo sapiens
6 UBQLN4 56893
Two-hybrid Homo sapiens
7 COL4A1 1282
Affinity Capture-MS Homo sapiens
8 COL6A1 1291
Affinity Capture-MS Homo sapiens
9 ZNF75A  
Affinity Capture-MS Homo sapiens
10 COL2A1 1280
Affinity Capture-MS Homo sapiens
11 PNN 5411
Affinity Capture-MS Homo sapiens
12 C14orf119  
Two-hybrid Homo sapiens
13 COL4A6 1288
Affinity Capture-MS Homo sapiens
14 EML4 27436
Affinity Capture-MS Homo sapiens
15 SQSTM1 8878
Affinity Capture-MS Homo sapiens
16 PLOD1 5351
Affinity Capture-MS Homo sapiens
17 KIF7 374654
Affinity Capture-MS Homo sapiens
18 ARMC8 25852
Affinity Capture-MS Homo sapiens
19 PRPF31 26121
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
20 FN1 2335
Affinity Capture-MS Homo sapiens
21 COL6A2 1292
Affinity Capture-MS Homo sapiens
22 C1QTNF6 114904
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
23 PLOD2 5352
Affinity Capture-MS Homo sapiens
24 PLOD3 8985
Affinity Capture-MS Homo sapiens
25 ZMYM6  
Affinity Capture-MS Homo sapiens
26 MLLT4 4301
Affinity Capture-MS Homo sapiens
27 SCARA3  
Affinity Capture-MS Homo sapiens
28 COL5A1 1289
Affinity Capture-MS Homo sapiens
29 COL12A1 1303
Affinity Capture-MS Homo sapiens
30 KLHDC10 23008
Affinity Capture-MS Homo sapiens
31 COL3A1 1281
Affinity Capture-MS Homo sapiens
32 CACNA1A  
Two-hybrid Homo sapiens
33 VHL  
Affinity Capture-MS Homo sapiens
34 AVPR2  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
35 SGTA 6449
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
36 FERMT1 55612
Affinity Capture-MS Homo sapiens
37 COLGALT1 79709
Affinity Capture-MS Homo sapiens
38 POTEI 653269
Affinity Capture-MS Homo sapiens
39 FBXO11  
Affinity Capture-MS Homo sapiens
40 ZMYM2  
Affinity Capture-MS Homo sapiens
41 LNX1  
Two-hybrid Homo sapiens
42 COL18A1 80781
Affinity Capture-MS Homo sapiens
43 COL4A2 1284
Affinity Capture-MS Homo sapiens
44 COL21A1 81578
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which C1QTNF1 is involved
No pathways found





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