Gene description for COLGALT1
Gene name collagen beta(1-O)galactosyltransferase 1
Gene symbol COLGALT1
Other names/aliases GLT25D1
Species Homo sapiens
 Database cross references - COLGALT1
ExoCarta ExoCarta_79709
Entrez Gene 79709
HGNC 26182
UniProt Q8NBJ5  
 COLGALT1 identified in exosomes derived from the following tissue/cell type
Bladder cancer cells 20224111    
 Gene ontology annotations for COLGALT1
Molecular Function
    procollagen galactosyltransferase activity GO:0050211 IEA
Biological Process
    metabolic process GO:0008152 IEA
    extracellular matrix organization GO:0030198 TAS
Subcellular Localization
    endoplasmic reticulum lumen GO:0005788 TAS
    membrane GO:0016020 IDA
 Experiment description of studies that identified COLGALT1 in exosomes
1
Experiment ID 76
ISEV standards
EM
EV Biophysical techniques
TSG101|GAPDH|HSP90
EV Cytosolic markers
CD81|CD9|CD63|LAMP1|MHCI
EV Membrane markers
HSP90B1
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A.
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
 Protein-protein interactions for COLGALT1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which COLGALT1 is involved
PathwayEvidenceSource
Collagen biosynthesis and modifying enzymes TAS Reactome





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