Gene description for RBMX
Gene name
RNA binding motif protein, X-linked
Gene symbol
RBMX
Other names/aliases
HNRNPG HNRPG RBMXP1 RBMXRT RNMX hnRNP-G
Species
Homo sapiens
Database cross references - RBMX
ExoCarta
ExoCarta_27316
Entrez Gene
27316
HGNC
9910
MIM
300199
UniProt
P38159
RBMX identified in exosomes derived from the following tissue/cell type
Endothelial cells
26027894
Ovarian cancer cells
23333927
Ovarian cancer cells
23333927
Gene ontology annotations for RBMX
Experiment description of studies that identified RBMX in exosomes
1
Experiment ID
226
ISEV standards
✔
EM
EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✔
CD9|FLOT1
EV Membrane markers
✔
LMNA|H2AFX|ATP5A1|TOMM20
EV Negative markers
✘
EV Particle analysis
Identified molecule
mRNA
Identification method
Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID
26027894
Organism
Homo sapiens
Experiment description
Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors
Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name
Journal of Extracellular Vesicles
Publication year
2015
Sample
Endothelial cells
Sample name
HMEC-1
Isolation/purification methods
Differential ultracentrifugation Sucrose density gradient
Flotation density
1.10 g/mL
Molecules identified in the study
miRNA Protein snoRNA lncRNA yRNA snRNA mRNA ncRNA mtRNA vtRNA scaRNA lincRNA
Methods used in the study
Small RNA sequencing (Illumina HiSeq 2000 (Solexa) Western blotting
2
Experiment ID
211
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
cytochrome c|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
3
Experiment ID
212
ISEV standards
✔
CEM
EV Biophysical techniques
✔
TSG101|Alix
EV Cytosolic markers
✔
EpCAM|TFRC
EV Membrane markers
✔
Cytochrome C|GOLGA2
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for RBMX
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
RBM7
Two-hybrid
Homo sapiens
2
HNRNPK
3190
Two-hybrid
Homo sapiens
3
SORBS3
10174
Two-hybrid
Homo sapiens
4
KHDRBS2
Two-hybrid
Homo sapiens
Affinity Capture-Western
Homo sapiens
5
KHDRBS3
Two-hybrid
Homo sapiens
6
ZFHX3
Affinity Capture-MS
Homo sapiens
7
LNX
Two-hybrid
Homo sapiens
8
FXR2
9513
Two-hybrid
Homo sapiens
9
CIRBP
1153
Two-hybrid
Homo sapiens
10
PSMF1
Two-hybrid
Homo sapiens
11
MGC2560
Two-hybrid
Homo sapiens
12
TRA2B
6434
Affinity Capture-Western
Homo sapiens
Reconstituted Complex
Homo sapiens
Invitro
Homo sapiens
Invivo
Homo sapiens
Two-hybrid
Homo sapiens
13
CCDC33
80125
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which RBMX is involved