Gene description for Srsf3
Gene name serine/arginine-rich splicing factor 3
Gene symbol Srsf3
Other names/aliases AL024116
Sfrs3
X16
Species Mus musculus
 Database cross references - Srsf3
ExoCarta ExoCarta_20383
Entrez Gene 20383
UniProt P84104  
 Srsf3 identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Srsf3
Molecular Function
    poly(A) RNA binding GO:0044822 ISO
    RNA binding GO:0003723 TAS
    phospholipase binding GO:0043274 IPI
    nucleotide binding GO:0000166 IEA
    nucleic acid binding GO:0003676 IEA
Biological Process
    mRNA transport GO:0051028 IEA
    RNA splicing GO:0008380 TAS
    transport GO:0006810 IEA
    insulin receptor signaling pathway GO:0008286 TAS
    mRNA processing GO:0006397 IEA
Subcellular Localization
    nuclear speck GO:0016607 IDA
    nucleus GO:0005634 IEA
    cytoplasm GO:0005737 IEA
 Experiment description of studies that identified Srsf3 in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Srsf3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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