Gene description for Srsf2
Gene name
serine/arginine-rich splicing factor 2
Gene symbol
Srsf2
Other names/aliases
D11Wsu175e MRF-1 Pr264 SC35 Sfrs10 Sfrs2
Species
Mus musculus
Database cross references - Srsf2
ExoCarta
ExoCarta_20382
Vesiclepedia
VP_20382
Entrez Gene
20382
UniProt
Q62093
Srsf2 identified in exosomes derived from the following tissue/cell type
Colon cancer cells
37309723
Mast cells
17486113
T-cell lymphoma cells
37309723
Gene ontology annotations for Srsf2
Experiment description of studies that identified Srsf2 in exosomes
1
Experiment ID
907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name
Proteomics
Publication year
2023
Sample
Colon cancer cells
Sample name
C26
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
15
MISEV standards
✔
EM
EV Biophysical techniques
✔
CD63
EV Enriched markers
✘
EV Negative markers
✘
EV Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
17486113
Organism
Mus musculus Homo sapiens
Experiment description
Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors
Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name
NCB
Publication year
2007
Sample
Mast cells
Sample name
MC9 Bone marrow-derived mast cells HMC-1
Isolation/purification methods
Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.11-1.21 g/mL
Molecules identified in the study
Protein mRNA miRNA
Methods used in the study
Mass spectrometry [MALDI TOF] Western blotting Microarray miRCURY LNA Array
3
Experiment ID
908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
37309723
Organism
Mus musculus
Experiment description
Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors
Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name
Proteomics
Publication year
2023
Sample
T-cell lymphoma cells
Sample name
EL4
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Srsf2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Fus
Two-hybrid
Mus musculus
Affinity Capture-Western
Mus musculus
View the network
image/svg+xml
Pathways in which Srsf2 is involved
No pathways found