Gene description for Srsf7
Gene name serine/arginine-rich splicing factor 7
Gene symbol Srsf7
Other names/aliases 35kDa
9430065L19Rik
9G8
NX-96
Sfrs7
Species Mus musculus
 Database cross references - Srsf7
ExoCarta ExoCarta_225027
Vesiclepedia VP_225027
Entrez Gene 225027
UniProt Q8BL97  
 Srsf7 identified in exosomes derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Srsf7
Molecular Function
    nucleotide binding GO:0000166 IEA
    protein binding GO:0005515 IPI
    poly(A) RNA binding GO:0044822 ISO
    nucleic acid binding GO:0003676 IEA
    zinc ion binding GO:0008270 IEA
    metal ion binding GO:0046872 IEA
    RNA binding GO:0003723 IEA
Biological Process
    transport GO:0006810 IEA
    mRNA processing GO:0006397 IEA
    mRNA transport GO:0051028 IEA
    RNA splicing GO:0008380 IEA
    negative regulation of mRNA splicing, via spliceosome GO:0048025 ISO
Subcellular Localization
    nucleus GO:0005634 IEA
    extracellular exosome GO:0070062 ISO
    cytoplasm GO:0005737 IEA
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Srsf7 in exosomes
1
Experiment ID 907
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
✔
EM
EV Biophysical techniques
✔
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
EV Enriched markers
✔
HSPA5
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S.
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Srsf7
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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