Experiment description of studies that identified Mov10 in sEVs

1 Experiment ID 907 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample Colon cancer cells Sample name C26 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 214 MISEV standards ✔ EM Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23658846     Organism Mus musculus Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Authors "Hassani K, Olivier M." Journal name PLoS Negl Trop Dis Publication year 2013 Sample Macrophages Sample name Leishmania-infected-Macrophage (J774A.1) Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Filtration Protease inhibitors Sucrose density gradient Filtration Ultracentrifugation Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

3 Experiment ID 215 MISEV standards ✔ EM Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23658846     Organism Mus musculus Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Authors "Hassani K, Olivier M." Journal name PLoS Negl Trop Dis Publication year 2013 Sample Macrophages Sample name LPS-treated-Macrophage (J774A.1) Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Filtration Protease inhibitors Sucrose density gradient Filtration Ultracentrifugation Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

4 Experiment ID 216 MISEV standards ✔ EM Biophysical techniques ✘ Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 23658846     Organism Mus musculus Experiment description Immunomodulatory impact of leishmania-induced macrophage exosomes: a comparative proteomic and functional analysis. Authors "Hassani K, Olivier M." Journal name PLoS Negl Trop Dis Publication year 2013 Sample Macrophages Sample name Normal-Macrophage (J774A.1) Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Filtration Protease inhibitors Sucrose density gradient Filtration Ultracentrifugation Flotation density 1.13-1.19 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry

5 Experiment ID 908 MISEV standards ✔ EM Biophysical techniques ✔ Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a Enriched markers ✔ HSPA5 Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 37309723     Organism Mus musculus Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S." Journal name Proteomics Publication year 2023 Sample T-cell lymphoma cells Sample name EL4 Isolation/purification methods Differential centrifugation Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for Mov10

Protein Interactor ExoCarta ID Identification method PubMed Species 1 Mcf2l   Co-fractionation Mus musculus 2 Fancd2   Affinity Capture-MS Mus musculus 3 MKRN1 23608 Affinity Capture-MS Homo sapiens 4 1110037F02Rik 66185 Co-fractionation Mus musculus 5 Snrnp40   Co-fractionation Mus musculus 6 Bcas2   Co-fractionation Mus musculus 7 Srsf7 225027 Co-fractionation Mus musculus 8 Smu1   Co-fractionation Mus musculus 9 Snrnp200 320632 Co-fractionation Mus musculus 10 Crnkl1   Co-fractionation Mus musculus 11 Fzr1   Affinity Capture-MS Mus musculus 12 Tfip11   Co-fractionation Mus musculus 13 Mov10l1   Co-fractionation Mus musculus 14 Nanog   Affinity Capture-MS Mus musculus Affinity Capture-MS Mus musculus 15 Cdk12   Co-fractionation Mus musculus 16 Snrpc 20630 Co-fractionation Mus musculus 17 Htatsf1   Co-fractionation Mus musculus 18 Slu7   Co-fractionation Mus musculus 19 Dhx8   Co-fractionation Mus musculus 20 Eed   Affinity Capture-MS Mus musculus 21 Trim71   Co-localization Mus musculus 22 Srsf3 20383 Co-fractionation Mus musculus 23 Snrnp70 20637 Co-fractionation Mus musculus 24 Rbm25   Co-fractionation Mus musculus 25 Adcy10   Co-fractionation Mus musculus View the network

Pathways in which Mov10 is involved

No pathways found