Gene description for Prpf4b
Gene name
PRP4 pre-mRNA processing factor 4 homolog B (yeast)
Gene symbol
Prpf4b
Other names/aliases
2610037H07 Prp4 Prp4k Prpk cbp143
Species
Mus musculus
Database cross references - Prpf4b
ExoCarta
ExoCarta_19134
Vesiclepedia
VP_19134
Entrez Gene
19134
UniProt
Q61136
Prpf4b identified in exosomes derived from the following tissue/cell type
Melanoma cells
34957415
Melanoma cells
34957415
Gene ontology annotations for Prpf4b
Experiment description of studies that identified Prpf4b in exosomes
1
Experiment ID
1117
MISEV standards
✘
Biophysical techniques
✔
Cd81|Icam1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H.
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
2
Experiment ID
1118
MISEV standards
✘
Biophysical techniques
✔
Cd81|Icam1
Enriched markers
✘
Negative markers
✔
NTA
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
34957415
Organism
Mus musculus
Experiment description
Melanoma-derived small extracellular vesicles induce lymphangiogenesis and metastasis through an NGFR-dependent mechanism
Authors
GarcÃa-Silva S, Benito-MartÃn A, Nogués L, Hernández-Barranco A, Mazariegos MS, Santos V, Hergueta-Redondo M, Ximénez-Embún P, Kataru RP, Lopez AA, Merino C, Sánchez-Redondo S, Graña-Castro O, Matei I, Nicolás-Avila JÃ, Torres-Ruiz R, RodrÃguez-Perales S, MartÃnez L, Pérez-MartÃnez M, Mata G, Szumera-Ciećkiewicz A, Kalinowska I, Saltari A, MartÃnez-Gómez JM, Hogan SA, Saragovi HU, Ortega S, Garcia-Martin C, Boskovic J, Levesque MP, Rutkowski P, Hidalgo A, Muñoz J, MegÃas D, Mehrara BJ, Lyden D, Peinado H.
Journal name
Nat Cancer
Publication year
2021
Sample
Melanoma cells
Sample name
B16-F1R2
Isolation/purification methods
Differential centrifugation Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectrometry
Protein-protein interactions for Prpf4b
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
Sf3a3
75062
Co-fractionation
Mus musculus
2
Ddx5
13207
Co-fractionation
Mus musculus
3
Prpf18
Co-fractionation
Mus musculus
4
Prpf8
192159
Co-fractionation
Mus musculus
5
Cluh
Affinity Capture-MS
Mus musculus
6
Pou5f1
Affinity Capture-MS
Mus musculus
7
Cactin
Co-fractionation
Mus musculus
8
1110037F02Rik
66185
Co-fractionation
Mus musculus
9
Snrnp40
Co-fractionation
Mus musculus
10
Bcas2
Co-fractionation
Mus musculus
11
Srsf7
225027
Co-fractionation
Mus musculus
12
Atxn1
Proximity Label-MS
Mus musculus
13
Foxp3
Affinity Capture-MS
Mus musculus
14
Cwc22
Co-fractionation
Mus musculus
15
Prpf3
70767
Co-fractionation
Mus musculus
16
Pnn
Co-fractionation
Mus musculus
17
Cwc15
Co-fractionation
Mus musculus
18
Thoc2
Co-fractionation
Mus musculus
19
Ppil4
Co-fractionation
Mus musculus
20
Srrm2
Co-fractionation
Mus musculus
21
Spen
Co-fractionation
Mus musculus
22
Cdk12
Co-fractionation
Mus musculus
23
Snrpc
20630
Co-fractionation
Mus musculus
24
Htatsf1
Co-fractionation
Mus musculus
25
Hnrnpm
76936
Co-fractionation
Mus musculus
26
Ddx41
Co-fractionation
Mus musculus
27
Prpf40a
Co-fractionation
Mus musculus
28
Srsf3
20383
Co-fractionation
Mus musculus
29
Zfp292
Co-fractionation
Mus musculus
30
Snrnp70
20637
Co-fractionation
Mus musculus
31
Ik
Co-fractionation
Mus musculus
32
Rbm25
Co-fractionation
Mus musculus
33
Paxbp1
Co-fractionation
Mus musculus
View the network
image/svg+xml
Pathways in which Prpf4b is involved