Gene description for SEC23IP
Gene name SEC23 interacting protein
Gene symbol SEC23IP
Other names/aliases MSTP053
P125
P125A
Species Homo sapiens
 Database cross references - SEC23IP
ExoCarta ExoCarta_11196
Entrez Gene 11196
HGNC 17018
UniProt Q9Y6Y8  
 SEC23IP identified in exosomes derived from the following tissue/cell type
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
 Gene ontology annotations for SEC23IP
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
    protein binding GO:0005515 IPI
    metal ion binding GO:0046872 IEA
Biological Process
    acrosome assembly GO:0001675 IEA
    single fertilization GO:0007338 IEA
    Golgi organization GO:0007030 TAS
    intracellular protein transport GO:0006886 TAS
Subcellular Localization
    intracellular membrane-bounded organelle GO:0043231 IDA
    perinuclear endoplasmic reticulum GO:0097038 IEA
    cytoplasm GO:0005737 TAS
    ER to Golgi transport vesicle membrane GO:0012507 IEA
    cis-Golgi network GO:0005801 IEA
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 TAS
    endoplasmic reticulum exit site GO:0070971 IEA
 Experiment description of studies that identified SEC23IP in exosomes
1
Experiment ID 211
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
cytochrome c|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 212
ISEV standards
CEM
EV Biophysical techniques
TSG101|Alix
EV Cytosolic markers
EpCAM|TFRC
EV Membrane markers
Cytochrome C|GOLGA2
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K.
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SEC23IP
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which SEC23IP is involved
No pathways found





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