Gene description for RAB5A
Gene name RAB5A, member RAS oncogene family
Gene symbol RAB5A
Other names/aliases RAB5
Species Homo sapiens
 Database cross references - RAB5A
ExoCarta ExoCarta_5868
Vesiclepedia VP_5868
Entrez Gene 5868
HGNC 9783
MIM 179512
UniProt P20339  
 RAB5A identified in sEVs derived from the following tissue/cell type
B cells 20458337    
B cells 20458337    
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Mesenchymal stem cells Unpublished / Not applicable
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Platelets 25332113    
Platelets 25332113    
Platelets 25332113    
Prostate cancer cells 25844599    
Prostate cancer cells 25844599    
Retinal pigment epithelial cells 35333565    
Retinal pigment epithelial cells 35333565    
Serum 25844599    
Serum 25844599    
Serum 25844599    
Serum 25844599    
Serum 25844599    
Serum 25844599    
Squamous carcinoma cells 20124223    
Thymus 23844026    
Urine 15326289    
Urine 21595033    
Urine 21595033    
Urine 21595033    
Urine 22418980    
Urine 22418980    
 Gene ontology annotations for RAB5A
Molecular Function
    GTPase activity GO:0003924 IBA
    GTPase activity GO:0003924 IDA
    G protein activity GO:0003925 IEA
    protein binding GO:0005515 IPI
    GTP binding GO:0005525 IDA
    GDP binding GO:0019003 IDA
    membrane scission GTPase motor activity GO:1990606 IEA
Biological Process
    intracellular protein transport GO:0006886 IBA
    endocytosis GO:0006897 IBA
    endocytosis GO:0006897 IDA
    phagocytosis GO:0006909 IEA
    receptor internalization GO:0031623 IMP
    synaptic vesicle recycling GO:0036465 IDA
    modulation by host of viral process GO:0044788 IMP
    early endosome to late endosome transport GO:0045022 IMP
    positive regulation of exocytosis GO:0045921 IMP
    regulation of long-term neuronal synaptic plasticity GO:0048169 IBA
    regulation of endosome size GO:0051036 IMP
    regulation of filopodium assembly GO:0051489 IDA
    canonical Wnt signaling pathway GO:0060070 IDA
    amyloid-beta clearance by transcytosis GO:0150093 IGI
    regulation of synaptic vesicle exocytosis GO:2000300 IMP
    regulation of autophagosome assembly GO:2000785 TAS
Subcellular Localization
    ruffle GO:0001726 IEA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
    endosome GO:0005768 ISS
    early endosome GO:0005769 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IEA
    synaptic vesicle GO:0008021 ISS
    endosome membrane GO:0010008 IDA
    endosome membrane GO:0010008 TAS
    endomembrane system GO:0012505 IBA
    actin cytoskeleton GO:0015629 IEA
    endocytic vesicle GO:0030139 IBA
    axon GO:0030424 IBA
    axon GO:0030424 ISS
    dendrite GO:0030425 IBA
    dendrite GO:0030425 ISS
    clathrin-coated endocytic vesicle membrane GO:0030669 TAS
    phagocytic vesicle membrane GO:0030670 IEA
    synaptic vesicle membrane GO:0030672 IBA
    early endosome membrane GO:0031901 TAS
    early phagosome GO:0032009 ISS
    somatodendritic compartment GO:0036477 IDA
    melanosome GO:0042470 IEA
    neuronal cell body GO:0043025 ISS
    terminal bouton GO:0043195 IDA
    intracellular membrane-bounded organelle GO:0043231 IDA
    axon terminus GO:0043679 ISS
    membrane raft GO:0045121 IEA
    phagocytic vesicle GO:0045335 ISS
    extracellular exosome GO:0070062 HDA
    cytoplasmic side of early endosome membrane GO:0098559 IMP
    postsynaptic early endosome GO:0098842 IBA
 Experiment description of studies that identified RAB5A in sEVs
1
Experiment ID 80
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis -Sample 2
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
2
Experiment ID 81
MISEV standards
Biophysical techniques
CD81|MHCII
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20458337    
Organism Homo sapiens
Experiment description MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis - Sample 3
Authors "Buschow SI, van Balkom BW, Aalberts M, Heck AJ, Wauben M, Stoorvogel W."
Journal name ICB
Publication year 2010
Sample B cells
Sample name RN (HLA-DR15)
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Immunobeads (MHC Class II)
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [FT-ICR]
Western blotting
3
Experiment ID 76
MISEV standards
EM
Biophysical techniques
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
HSP90B1
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
4
Experiment ID 489
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 490
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 491
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
7
Experiment ID 492
MISEV standards
EM
Biophysical techniques
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
Canx
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
8
Experiment ID 426
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
9
Experiment ID 427
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 497
MISEV standards
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 498
MISEV standards
EM
Biophysical techniques
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 20
MISEV standards
EM
Biophysical techniques
HSP90|CD63|CD81|LAMP1
Enriched markers
GOLGA2|cytochrome c
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
13
Experiment ID 21
MISEV standards
EM|IEM
Biophysical techniques
Alix|TSG101|HSP70|CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
14
Experiment ID 207
MISEV standards
EM
Biophysical techniques
TSG101|HSP70|FLOT1
Enriched markers
VDAC
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 208
MISEV standards
EM
Biophysical techniques
TSG101|HSP70|FLOT1
Enriched markers
VDAC
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
16
Experiment ID 209
MISEV standards
Biophysical techniques
TSG101|HSP70|FLOT1
Enriched markers
VDAC
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
17
Experiment ID 285
MISEV standards
CEM
Biophysical techniques
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
Negative markers
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
18
Experiment ID 1203
MISEV standards
EM
Biophysical techniques
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
19
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 419
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
22
Experiment ID 420
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 1275
MISEV standards
Biophysical techniques
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
24
Experiment ID 1280
MISEV standards
Biophysical techniques
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 363
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 364
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 365
MISEV standards
Biophysical techniques
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
DCLK1
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 235
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
29
Experiment ID 237
MISEV standards
EM
Biophysical techniques
TSG101|Alix|HSC70|GAPDH
Enriched markers
HSP90B1
Negative markers
qNano
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
30
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
31
Experiment ID 488
MISEV standards
EM
Biophysical techniques
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
32
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
33
Experiment ID 211
MISEV standards
EM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
cytochrome c|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
34
Experiment ID 212
MISEV standards
CEM
Biophysical techniques
TSG101|Alix|EpCAM|TFRC
Enriched markers
Cytochrome C|GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
35
Experiment ID 434
MISEV standards
Biophysical techniques
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 435
MISEV standards
Biophysical techniques
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
CANX
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
37
Experiment ID 231
MISEV standards
Biophysical techniques
Alix|CD63|CD9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 232
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
39
Experiment ID 233
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25332113    
Organism Homo sapiens
Experiment description Lipidomic and proteomic characterization of platelet extracellular vesicle subfractions from senescent platelets
Authors "Pienimaeki-Roemer A, Kuhlmann K, Bottcher A, Konovalova T, Black A, Orso E, Liebisch G, Ahrens M, Eisenacher M, Meyer HE, Schmitz G."
Journal name Transfusion
Publication year 2015
Sample Platelets
Sample name PL-Exs - Rep 3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Optiprep density gradient
Flotation density 1.12-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
40
Experiment ID 274
MISEV standards
EM
Biophysical techniques
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
AIF
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel resistant
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.18 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Flow cytometry
Western blotting
41
Experiment ID 275
MISEV standards
EM
Biophysical techniques
TSG101|Alix|RAB5A|CD9|CD82|CD63|CD81
Enriched markers
AIF
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
42
Experiment ID 834
MISEV standards
EM
Biophysical techniques
LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
43
Experiment ID 835
MISEV standards
EM
Biophysical techniques
CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101
Enriched markers
CANX
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35333565    
Organism Homo sapiens
Experiment description LAMP2A regulates the loading of proteins into exosomes
Authors "Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P"
Journal name Sci Adv
Publication year 2022
Sample Retinal pigment epithelial cells
Sample name ARPE-19
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
44
Experiment ID 276
MISEV standards
Biophysical techniques
Alix|RAB5A|CD9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Serum
Sample name Serum - Docetaxel resistant castration resistant prostate cancer patient 1
Isolation/purification methods Filtration
Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
45
Experiment ID 277
MISEV standards
Biophysical techniques
Alix|RAB5A|CD9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Serum
Sample name Serum - Docetaxel resistant castration resistant prostate cancer patient 2
Isolation/purification methods Filtration
Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
46
Experiment ID 278
MISEV standards
Biophysical techniques
Alix|RAB5A|CD9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Serum
Sample name Serum - Docetaxel resistant castration resistant prostate cancer patient 3
Isolation/purification methods Filtration
Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
47
Experiment ID 279
MISEV standards
Biophysical techniques
Alix|RAB5A
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Serum
Sample name Serum - Docetaxel sensitive castration resistant prostate cancer patient 4
Isolation/purification methods Filtration
Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
48
Experiment ID 280
MISEV standards
Biophysical techniques
Alix|RAB5A
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Serum
Sample name Serum - Docetaxel sensitive castration resistant prostate cancer patient 5
Isolation/purification methods Filtration
Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
49
Experiment ID 281
MISEV standards
Biophysical techniques
Alix|RAB5A|CD9
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Western blotting
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors "Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T."
Journal name Oncotarget
Publication year 2015
Sample Serum
Sample name Serum - Docetaxel sensitive castration resistant prostate cancer patient 6
Isolation/purification methods Filtration
Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
50
Experiment ID 191
MISEV standards
Biophysical techniques
Alix|CD81|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
51
Experiment ID 217
MISEV standards
EM
Biophysical techniques
TSG101|CD81|CD9|CD63
Enriched markers
Negative markers
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
52
Experiment ID 13
MISEV standards
IEM
Biophysical techniques
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 15326289    
Organism Homo sapiens
Experiment description Identification and proteomic profiling of exosomes in human urine.
Authors "Pisitkun T, Shen RF, Knepper MA"
Journal name PNAS
Publication year 2004
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LCQ DECA XP]
Western blotting
53
Experiment ID 193
MISEV standards
EM
Biophysical techniques
CD63|CD9
Enriched markers
PHB
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
54
Experiment ID 194
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of basement membrane nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
55
Experiment ID 195
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21595033    
Organism Homo sapiens
Experiment description Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors "Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name Proteomics
Publication year 2011
Sample Urine
Sample name Urine - Patients of early IgA nephropathy
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
56
Experiment ID 196
MISEV standards
EM
Biophysical techniques
Alix|TSG101|HSP70|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal high density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
57
Experiment ID 197
MISEV standards
EM
Biophysical techniques
Alix|TSG101|HSP70|CD9
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22418980    
Organism Homo sapiens
Experiment description A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors "Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name Kidney Int
Publication year 2012
Sample Urine
Sample name Urine - Normal low density
Isolation/purification methods Differential centrifugation
Sucrose cushion
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for RAB5A
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC22B 9554
Proximity Label-MS Homo sapiens
2 ITGB1 3688
Proximity Label-MS Homo sapiens
3 APPL2 55198
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
4 ARHGAP1 392
Proximity Label-MS Homo sapiens
5 WDR6 11180
Proximity Label-MS Homo sapiens
6 HOOK1  
Proximity Label-MS Homo sapiens
7 UHRF1BP1 54887
Proximity Label-MS Homo sapiens
8 SEC16A 9919
Proximity Label-MS Homo sapiens
9 LDHB 3945
Co-fractionation Homo sapiens
10 LLGL1 3996
Proximity Label-MS Homo sapiens
11 RIN3  
Two-hybrid Homo sapiens
12 ATE1 11101
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
13 ATP13A2  
Co-localization Homo sapiens
14 JPH1 56704
Proximity Label-MS Homo sapiens
15 RABGGTB 5876
Affinity Capture-MS Homo sapiens
16 SOX2  
Affinity Capture-MS Homo sapiens
17 ALS2CL  
Reconstituted Complex Homo sapiens
18 PTRH2 51651
Proximity Label-MS Homo sapiens
19 MON2 23041
Proximity Label-MS Homo sapiens
20 OSBPL9 114883
Proximity Label-MS Homo sapiens
21 APBB2  
Proximity Label-MS Homo sapiens
22 SMPD4 55627
Proximity Label-MS Homo sapiens
23 PTPN23 25930
Proximity Label-MS Homo sapiens
24 UNC5B 219699
Proximity Label-MS Homo sapiens
25 GDI1 2664
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 ABCD3 5825
Proximity Label-MS Homo sapiens
27 GRIK4  
FRET Homo sapiens
28 PIK3C3 5289
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
29 AP1AR 55435
Proximity Label-MS Homo sapiens
30 HERC2 8924
Affinity Capture-Western Homo sapiens
31 USP33  
Proximity Label-MS Homo sapiens
32 HYPM  
Affinity Capture-MS Homo sapiens
33 SLC12A7 10723
Proximity Label-MS Homo sapiens
34 ZFYVE9  
Proximity Label-MS Homo sapiens
35 TFRC 7037
Proximity Label-MS Homo sapiens
36 STX12 23673
Proximity Label-MS Homo sapiens
37 TMEM87A 25963
Proximity Label-MS Homo sapiens
38 KIF14 9928
Affinity Capture-MS Homo sapiens
39 NOTCH2 4853
Proximity Label-MS Homo sapiens
40 CAMLG 819
Proximity Label-MS Homo sapiens
41 UNK  
Affinity Capture-RNA Homo sapiens
42 RABGEF1 27342
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
43 ATG9A 79065
Co-fractionation Homo sapiens
44 HTATIP2 10553
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
PCA Homo sapiens
45 TMX1 81542
Proximity Label-MS Homo sapiens
46 VPS51 738
Proximity Label-MS Homo sapiens
47 MCAM 4162
Proximity Label-MS Homo sapiens
48 PDXDC1 23042
Proximity Label-MS Homo sapiens
49 CLCC1 23155
Proximity Label-MS Homo sapiens
50 Inpp5b  
Affinity Capture-MS Mus musculus
51 PIGT 51604
Affinity Capture-MS Homo sapiens
52 GORASP2 26003
Proximity Label-MS Homo sapiens
53 ITM2C 81618
Proximity Label-MS Homo sapiens
54 CARD16  
Affinity Capture-Western Homo sapiens
55 FLOT2 2319
Proximity Label-MS Homo sapiens
56 VPS18 57617
Proximity Label-MS Homo sapiens
57 LRP8 7804
Proximity Label-MS Homo sapiens
58 ZDHHC20 253832
Proximity Label-MS Homo sapiens
59 PTGIR  
Affinity Capture-Western Homo sapiens
60 RAB37 326624
Two-hybrid Homo sapiens
61 DST 667
Proximity Label-MS Homo sapiens
62 TMPO 7112
Proximity Label-MS Homo sapiens
63 TECPR2  
Proximity Label-MS Homo sapiens
64 SV2A 9900
Proximity Label-MS Homo sapiens
65 FAM83B  
Proximity Label-MS Homo sapiens
66 FAM129B 64855
Proximity Label-MS Homo sapiens
67 NEO1 4756
Proximity Label-MS Homo sapiens
68 VAMP8 8673
Proximity Label-MS Homo sapiens
69 LRRC59 55379
Proximity Label-MS Homo sapiens
70 CDCA3 83461
Proximity Label-MS Homo sapiens
71 GRIPAP1 56850
Proximity Label-MS Homo sapiens
72 ERBB2IP 55914
Proximity Label-MS Homo sapiens
73 DLG1 1739
Proximity Label-MS Homo sapiens
74 BCAP31 10134
Proximity Label-MS Homo sapiens
75 TMEM199  
Proximity Label-MS Homo sapiens
76 ATP6AP2 10159
Proximity Label-MS Homo sapiens
77 PRMT9  
Affinity Capture-MS Homo sapiens
78 MAP3K14  
Affinity Capture-Western Homo sapiens
79 WLS 79971
Proximity Label-MS Homo sapiens
80 SSUH2  
Affinity Capture-MS Homo sapiens
81 RPA3 6119
Proximity Label-MS Homo sapiens
82 SNX17 9784
Proximity Label-MS Homo sapiens
83 RINT1 60561
Proximity Label-MS Homo sapiens
84 DLST 1743
Affinity Capture-MS Homo sapiens
85 RPL35A 6165
Affinity Capture-MS Homo sapiens
86 FAM21C 253725
Proximity Label-MS Homo sapiens
87 DUSP9  
Affinity Capture-MS Homo sapiens
88 ITSN1 6453
PCA Homo sapiens
89 EFNB2 1948
Proximity Label-MS Homo sapiens
90 SNX5 27131
Proximity Label-MS Homo sapiens
91 KCNA5  
Co-localization Homo sapiens
92 GOLGB1 2804
Proximity Label-MS Homo sapiens
93 PFAS 5198
Proximity Label-MS Homo sapiens
94 FLVCR1 28982
Proximity Label-MS Homo sapiens
95 GGA3 23163
Proximity Label-MS Homo sapiens
96 CHML  
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
97 TMEM57  
Proximity Label-MS Homo sapiens
98 TGFBR2 7048
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
99 SCYL3 57147
Proximity Label-MS Homo sapiens
100 MACF1 23499
Proximity Label-MS Homo sapiens
101 IL1B  
Affinity Capture-MS Homo sapiens
102 PIK3R4 30849
Proximity Label-MS Homo sapiens
103 TRIP11 9321
Proximity Label-MS Homo sapiens
104 RAB11FIP1 80223
Proximity Label-MS Homo sapiens
105 WIF1 11197
Affinity Capture-MS Homo sapiens
106 VAMP7 6845
Proximity Label-MS Homo sapiens
107 COL1A2 1278
Affinity Capture-MS Homo sapiens
108 FAM219A 203259
Proximity Label-MS Homo sapiens
109 RAB2A 5862
Co-fractionation Homo sapiens
110 PHACTR4 65979
Proximity Label-MS Homo sapiens
111 GOLGA5 9950
Proximity Label-MS Homo sapiens
112 SH3GLB1 51100
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
113 RAB11A 8766
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
114 ENTPD6  
Affinity Capture-MS Homo sapiens
115 EPHA2 1969
Proximity Label-MS Homo sapiens
116 TXNIP 10628
Affinity Capture-Western Homo sapiens
117 CISD2 493856
Proximity Label-MS Homo sapiens
118 RAB5C 5878
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 VANGL1 81839
Proximity Label-MS Homo sapiens
120 SNX29  
Proximity Label-MS Homo sapiens
121 SCAMP3 10067
Proximity Label-MS Homo sapiens
122 CTNND1 1500
Proximity Label-MS Homo sapiens
123 KIF16B 55614
Proximity Label-MS Homo sapiens
124 LDHA 3939
Co-fractionation Homo sapiens
125 DDHD2 23259
Proximity Label-MS Homo sapiens
126 KIF23 9493
Affinity Capture-MS Homo sapiens
127 OSBPL10  
Proximity Label-MS Homo sapiens
128 NDRG1 10397
Proximity Label-MS Homo sapiens
129 BAG3 9531
Affinity Capture-MS Homo sapiens
Affinity Capture-Luminescence Homo sapiens
130 TSC2 7249
Co-purification Homo sapiens
131 GJA1 2697
Proximity Label-MS Homo sapiens
132 FZD4 8322
Affinity Capture-Western Homo sapiens
133 RPA2 6118
Proximity Label-MS Homo sapiens
134 ARFGAP2 84364
Proximity Label-MS Homo sapiens
135 FGF4  
Affinity Capture-MS Homo sapiens
136 PACSIN2 11252
Proximity Label-MS Homo sapiens
137 SRPR 6734
Proximity Label-MS Homo sapiens
138 HRAS 3265
Affinity Capture-Western Homo sapiens
139 FAM21A 387680
Proximity Label-MS Homo sapiens
140 VAMP2 6844
Proximity Label-MS Homo sapiens
141 FFAR1  
Affinity Capture-MS Homo sapiens
142 GOLGA7 51125
Affinity Capture-MS Homo sapiens
143 VANGL2  
Proximity Label-MS Homo sapiens
144 NCOR1  
Affinity Capture-MS Homo sapiens
145 PGK1 5230
Proximity Label-MS Homo sapiens
146 WDR41  
Proximity Label-MS Homo sapiens
147 ELOVL1 64834
Affinity Capture-MS Homo sapiens
148 DIAPH3 81624
Proximity Label-MS Homo sapiens
149 WDR7 23335
Proximity Label-MS Homo sapiens
150 RAB5B 5869
Affinity Capture-MS Homo sapiens
151 GGA1 26088
Proximity Label-MS Homo sapiens
152 SUN2 25777
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
153 NCOA7  
Proximity Label-MS Homo sapiens
154 RAB4A  
Affinity Capture-MS Bos taurus
Affinity Capture-Western Bos taurus
155 SDCBP 6386
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
156 FGFR1 2260
Affinity Capture-MS Homo sapiens
157 TDRKH  
Proximity Label-MS Homo sapiens
158 KDR  
Affinity Capture-Western Homo sapiens
159 LMAN1 3998
Proximity Label-MS Homo sapiens
160 KIAA1715 80856
Proximity Label-MS Homo sapiens
161 CHMP7 91782
Proximity Label-MS Homo sapiens
162 SLC1A5 6510
Proximity Label-MS Homo sapiens
163 RABL3 285282
Proximity Label-MS Homo sapiens
164 VPS45 11311
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
165 RUFY1 80230
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
166 RAI14 26064
Proximity Label-MS Homo sapiens
167 RNF115  
Affinity Capture-Western Homo sapiens
168 SNAP47 116841
Proximity Label-MS Homo sapiens
169 RABEP2 511736
Affinity Capture-MS Bos taurus
Affinity Capture-Western Bos taurus
170 RAP1B 5908
Co-fractionation Homo sapiens
171 PMAIP1  
Affinity Capture-MS Homo sapiens
172 RIN1 9610
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
173 RAP1A 5906
Co-fractionation Homo sapiens
174 JAG2  
Proximity Label-MS Homo sapiens
175 STX5 6811
Proximity Label-MS Homo sapiens
176 SLC12A4 6560
Proximity Label-MS Homo sapiens
177 UPK1A 11045
Affinity Capture-MS Homo sapiens
178 RBSN 64145
Far Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
179 NDC1 55706
Proximity Label-MS Homo sapiens
180 VPS11 55823
Proximity Label-MS Homo sapiens
181 CCDC25 55246
Proximity Label-MS Homo sapiens
182 KIF3B 9371
Affinity Capture-Western Homo sapiens
183 MINK1 50488
Proximity Label-MS Homo sapiens
184 DNAAF2  
Affinity Capture-MS Homo sapiens
185 RNF34  
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
186 RAB8B 51762
Co-fractionation Homo sapiens
187 ADCY9 115
Proximity Label-MS Homo sapiens
188 HDDC3  
Affinity Capture-MS Homo sapiens
189 CIT 11113
Affinity Capture-MS Homo sapiens
190 C1orf52  
Affinity Capture-MS Homo sapiens
191 SPECC1 92521
Affinity Capture-MS Homo sapiens
192 TYRP1 7306
Co-fractionation Homo sapiens
193 ARFIP1 27236
Proximity Label-MS Homo sapiens
194 SCYL2 55681
Proximity Label-MS Homo sapiens
195 SMAP1 60682
Proximity Label-MS Homo sapiens
196 FAM91A1 157769
Proximity Label-MS Homo sapiens
197 SLC3A2 6520
Proximity Label-MS Homo sapiens
198 FAM134B 54463
Proximity Label-MS Homo sapiens
199 C19orf70  
Affinity Capture-MS Homo sapiens
200 SLC6A15 55117
Proximity Label-MS Homo sapiens
201 TGFA  
Affinity Capture-MS Homo sapiens
202 PEAK1 79834
Proximity Label-MS Homo sapiens
203 DDRGK1 65992
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
204 SLC12A6 9990
Proximity Label-MS Homo sapiens
205 WDR44 54521
Proximity Label-MS Homo sapiens
206 TMEM209 84928
Proximity Label-MS Homo sapiens
207 LEMD3  
Proximity Label-MS Homo sapiens
208 LMNA 4000
Proximity Label-MS Homo sapiens
209 OSBPL8 114882
Proximity Label-MS Homo sapiens
210 STX17 55014
Affinity Capture-MS Homo sapiens
211 RAB31 11031
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
212 DENND4C 55667
Proximity Label-MS Homo sapiens
213 MARK3 4140
Proximity Label-MS Homo sapiens
214 UHRF1BP1L 23074
Proximity Label-MS Homo sapiens
215 SLC38A2 54407
Proximity Label-MS Homo sapiens
216 TRIM13  
Proximity Label-MS Homo sapiens
217 EXOC3 11336
Proximity Label-MS Homo sapiens
218 VPS13B  
Proximity Label-MS Homo sapiens
219 MKNK1  
Affinity Capture-MS Homo sapiens
220 VTI1A 143187
Proximity Label-MS Homo sapiens
221 TACC1 6867
Proximity Label-MS Homo sapiens
222 C1orf35  
Affinity Capture-MS Homo sapiens
223 TSC1 7248
Proximity Label-MS Homo sapiens
224 TOR1AIP1 26092
Proximity Label-MS Homo sapiens
225 SLAMF1 6504
Affinity Capture-MS Homo sapiens
226 VPS33A 65082
Proximity Label-MS Homo sapiens
227 AUP1 550
Proximity Label-MS Homo sapiens
228 RAB8A 4218
Co-fractionation Homo sapiens
229 PLD3 23646
Proximity Label-MS Homo sapiens
230 BCL2L13 23786
Proximity Label-MS Homo sapiens
231 STX3 6809
Proximity Label-MS Homo sapiens
232 ATP1A1 476
Proximity Label-MS Homo sapiens
233 GOT1 2805
Affinity Capture-MS Homo sapiens
234 YKT6 10652
Proximity Label-MS Homo sapiens
235 IGF2R 3482
Proximity Label-MS Homo sapiens
236 KIAA1468 57614
Proximity Label-MS Homo sapiens
237 RPS6KC1  
Proximity Label-MS Homo sapiens
238 GLRX3 10539
Proximity Label-MS Homo sapiens
239 SH3KBP1 30011
Affinity Capture-Western Homo sapiens
240 CKAP4 10970
Proximity Label-MS Homo sapiens
241 PTRF 284119
Affinity Capture-MS Homo sapiens
242 IRS4 8471
Proximity Label-MS Homo sapiens
243 VPS8 23355
Proximity Label-MS Homo sapiens
244 NLRP3  
Affinity Capture-Western Homo sapiens
245 CC2D1A 54862
Proximity Label-MS Homo sapiens
246 MTMR6 9107
Proximity Label-MS Homo sapiens
247 NUPL2 11097
Proximity Label-MS Homo sapiens
248 ATP6V1B2 526
Proximity Label-MS Homo sapiens
249 CLCN7 1186
Proximity Label-MS Homo sapiens
250 ZDHHC5 25921
Proximity Label-MS Homo sapiens
251 OCLN 100506658
Proximity Label-MS Homo sapiens
252 MARCKS 4082
Proximity Label-MS Homo sapiens
253 TPD52L2 7165
Proximity Label-MS Homo sapiens
254 SLC30A1 7779
Proximity Label-MS Homo sapiens
255 ROBO1 6091
Proximity Label-MS Homo sapiens
256 SHB 6461
Proximity Label-MS Homo sapiens
257 SYNE2 23224
Proximity Label-MS Homo sapiens
258 PTPN1 5770
Proximity Label-MS Homo sapiens
259 APBB1  
Proximity Label-MS Homo sapiens
260 STX4 6810
Affinity Capture-Western Homo sapiens
261 RTN4 57142
Proximity Label-MS Homo sapiens
262 TEX264 51368
Proximity Label-MS Homo sapiens
263 SNX3 8724
Proximity Label-MS Homo sapiens
264 PTPN12 5782
Proximity Label-MS Homo sapiens
265 CHMP5 51510
Co-localization Homo sapiens
266 STX8 9482
Proximity Label-MS Homo sapiens
267 DSC2 1824
Proximity Label-MS Homo sapiens
268 LSG1  
Proximity Label-MS Homo sapiens
269 SPRY4 81848
Proximity Label-MS Homo sapiens
270 CCDC47 57003
Proximity Label-MS Homo sapiens
271 RGPD6  
Proximity Label-MS Homo sapiens
272 MXRA7 439921
Proximity Label-MS Homo sapiens
273 MTDH 92140
Proximity Label-MS Homo sapiens
274 INPP5F  
Proximity Label-MS Homo sapiens
275 MAVS 57506
Proximity Label-MS Homo sapiens
276 ESYT2 57488
Proximity Label-MS Homo sapiens
277 ATP13A3 79572
Proximity Label-MS Homo sapiens
278 EHD1 10938
Proximity Label-MS Homo sapiens
279 APPL1 26060
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Proximity Label-MS Homo sapiens
280 EEA1 8411
FRET Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
281 PLEKHA1 59338
Proximity Label-MS Homo sapiens
282 NUP155 9631
Proximity Label-MS Homo sapiens
283 BSG 682
Proximity Label-MS Homo sapiens
284 UBR4 23352
Co-localization Homo sapiens
285 SLC1A3 6507
Proximity Label-MS Homo sapiens
286 EIF2AK3  
Proximity Label-MS Homo sapiens
287 SCFD1 23256
Proximity Label-MS Homo sapiens
288 CPNE8 144402
Proximity Label-MS Homo sapiens
289 ZFYVE16  
Proximity Label-MS Homo sapiens
290 ZDHHC19  
Affinity Capture-MS Homo sapiens
291 CXADR 1525
Proximity Label-MS Homo sapiens
292 RABEP1 9135
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Co-purification Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Proximity Label-MS Homo sapiens
293 BET1L 51272
Proximity Label-MS Homo sapiens
294 RAB4A 5867
Co-purification Homo sapiens
295 NUMB 8650
Proximity Label-MS Homo sapiens
296 SARAF  
Affinity Capture-MS Homo sapiens
297 PIKFYVE 200576
Proximity Label-MS Homo sapiens
298 PPP1R21 129285
Proximity Label-MS Homo sapiens
299 LRBA 987
Proximity Label-MS Homo sapiens
300 RAB3GAP1 22930
Proximity Label-MS Homo sapiens
301 SGSM3  
Two-hybrid Homo sapiens
302 PIK3R1 5295
Affinity Capture-Western Homo sapiens
303 ARL13B 200894
Proximity Label-MS Homo sapiens
304 ACSL4 2182
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
305 DNM1L 10059
Proximity Label-MS Homo sapiens
306 TOM1L2 146691
Proximity Label-MS Homo sapiens
307 ITM2B 9445
Proximity Label-MS Homo sapiens
308 SLC4A7 9497
Proximity Label-MS Homo sapiens
309 DUSP22  
Affinity Capture-MS Homo sapiens
310 TBC1D15 64786
Two-hybrid Homo sapiens
311 PCTP  
Affinity Capture-MS Homo sapiens
312 OLA1 29789
Proximity Label-MS Homo sapiens
313 SMCR8 140775
Proximity Label-MS Homo sapiens
314 ZAK 51776
Affinity Capture-MS Homo sapiens
315 CDC73  
Affinity Capture-MS Homo sapiens
316 KIAA1244  
Proximity Label-MS Homo sapiens
317 OCRL 4952
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
318 TBC1D22B  
Proximity Label-MS Homo sapiens
319 FERMT2 10979
Proximity Label-MS Homo sapiens
320 VAMP3 9341
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
321 PPP1R37 284352
Proximity Label-MS Homo sapiens
322 STIM1 6786
Proximity Label-MS Homo sapiens
323 NIPAL1  
Affinity Capture-MS Homo sapiens
324 GBF1 8729
Proximity Label-MS Homo sapiens
325 ECE1 1889
Proximity Label-MS Homo sapiens
326 OCIAD1 54940
Proximity Label-MS Homo sapiens
327 OSBPL11 114885
Proximity Label-MS Homo sapiens
328 ZFYVE28  
Co-localization Homo sapiens
329 SPTAN1 6709
Proximity Label-MS Homo sapiens
330 RABAC1 10567
Two-hybrid Homo sapiens
331 SNX30 401548
Proximity Label-MS Homo sapiens
332 RAB11B 9230
Co-fractionation Homo sapiens
333 SH3D19 152503
Proximity Label-MS Homo sapiens
334 SLC19A1 6573
Proximity Label-MS Homo sapiens
335 RPN1 6184
Co-fractionation Homo sapiens
336 FLII 2314
Affinity Capture-Western Homo sapiens
337 KTN1 3895
Proximity Label-MS Homo sapiens
338 ZC3HAV1 56829
Proximity Label-MS Homo sapiens
339 HAX1  
Affinity Capture-MS Homo sapiens
340 HLA-A 3105
Proximity Label-MS Homo sapiens
341 CHM 1121
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
342 FAM114A2  
Proximity Label-MS Homo sapiens
343 AKAP1 8165
Proximity Label-MS Homo sapiens
344 ACBD5 91452
Proximity Label-MS Homo sapiens
345 UBE2J1 51465
Proximity Label-MS Homo sapiens
346 DMXL2  
Proximity Label-MS Homo sapiens
347 DEPDC1B 55789
Proximity Label-MS Homo sapiens
348 FAM160A2 84067
Proximity Label-MS Homo sapiens
349 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
350 PVRL2 5819
Proximity Label-MS Homo sapiens
351 ALDH3A2 224
Proximity Label-MS Homo sapiens
352 GIPC1 10755
Proximity Label-MS Homo sapiens
353 SLC25A6 293
Affinity Capture-MS Homo sapiens
354 RAB3GAP2 25782
Proximity Label-MS Homo sapiens
355 JUP 3728
Proximity Label-MS Homo sapiens
356 SEC23IP 11196
Proximity Label-MS Homo sapiens
357 TOR1AIP2 163590
Proximity Label-MS Homo sapiens
358 LSR 51599
Proximity Label-MS Homo sapiens
359 KIAA1429 25962
Affinity Capture-MS Homo sapiens
360 VAMP4 8674
Proximity Label-MS Homo sapiens
361 EFNB1 1947
Proximity Label-MS Homo sapiens
362 TBC1D2B 23102
Proximity Label-MS Homo sapiens
363 RABL6 55684
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
364 MTSS1 9788
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
365 PDZD8 118987
Proximity Label-MS Homo sapiens
366 MBNL1 4154
Affinity Capture-MS Homo sapiens
367 INF2 64423
Proximity Label-MS Homo sapiens
368 LRRK2 120892
Affinity Capture-Western Homo sapiens
369 CASP1  
Affinity Capture-Western Homo sapiens
370 FRS2 10818
Proximity Label-MS Homo sapiens
371 RAB7A 7879
Two-hybrid Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Proximity Label-MS Homo sapiens
372 LRP2 4036
Proximity Label-MS Homo sapiens
373 BNIP2  
Proximity Label-MS Homo sapiens
374 SNX2 6643
Proximity Label-MS Homo sapiens
375 CCR1  
Affinity Capture-MS Homo sapiens
376 PYCARD 29108
Affinity Capture-Western Homo sapiens
377 CAV1 857
Proximity Label-MS Homo sapiens
378 NOTCH1 4851
Affinity Capture-Western Homo sapiens
379 IGF2BP2 10644
Co-fractionation Homo sapiens
380 RAB22A 57403
Affinity Capture-Western Homo sapiens
381 POR 5447
Proximity Label-MS Homo sapiens
382 ANKLE2 23141
Proximity Label-MS Homo sapiens
383 VTI1B 10490
Proximity Label-MS Homo sapiens
384 DERL2 51009
Affinity Capture-MS Homo sapiens
385 SNAP23 8773
Proximity Label-MS Homo sapiens
386 VAPA 9218
Proximity Label-MS Homo sapiens
387 RABEP2 79874
Reconstituted Complex Homo sapiens
388 AKAP12 9590
Proximity Label-MS Homo sapiens
389 TMF1 7110
Proximity Label-MS Homo sapiens
390 RIT2  
Biochemical Activity Homo sapiens
391 ARFGAP3 26286
Proximity Label-MS Homo sapiens
392 TSG101 7251
Co-localization Homo sapiens
393 CARD17  
Affinity Capture-Western Homo sapiens
394 BASP1 10409
Proximity Label-MS Homo sapiens
395 LNPEP 4012
Proximity Label-MS Homo sapiens
396 SLC30A4 7782
Proximity Label-MS Homo sapiens
397 SNX6 58533
Proximity Label-MS Homo sapiens
398 SLC12A2 6558
Proximity Label-MS Homo sapiens
399 FNDC5  
Affinity Capture-MS Homo sapiens
400 CTSD 1509
Co-fractionation Homo sapiens
401 MARK2 2011
Proximity Label-MS Homo sapiens
402 SLC39A14 23516
Proximity Label-MS Homo sapiens
403 SLC39A10 57181
Proximity Label-MS Homo sapiens
404 VRK2 7444
Proximity Label-MS Homo sapiens
405 YES1 7525
Proximity Label-MS Homo sapiens
406 CPD 1362
Proximity Label-MS Homo sapiens
407 SCRIB 23513
Proximity Label-MS Homo sapiens
408 STX7 8417
Proximity Label-MS Homo sapiens
409 UNC5C  
Proximity Label-MS Homo sapiens
410 SEMA4C 54910
Proximity Label-MS Homo sapiens
411 CARD18  
Affinity Capture-Western Homo sapiens
412 AGTR1  
Reconstituted Complex Homo sapiens
413 PGRMC2 10424
Proximity Label-MS Homo sapiens
414 EXD2  
Proximity Label-MS Homo sapiens
415 GOPC 57120
Proximity Label-MS Homo sapiens
416 KIAA0226  
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
417 PHF11 51131
Affinity Capture-MS Homo sapiens
418 NME2 4831
Two-hybrid Homo sapiens
419 TF 7018
Co-fractionation Homo sapiens
420 TMEM2 23670
Proximity Label-MS Homo sapiens
421 C18orf21  
Affinity Capture-MS Homo sapiens
422 LAMTOR1 55004
Proximity Label-MS Homo sapiens
423 TNF  
Affinity Capture-Western Homo sapiens
424 TBC1D17 79735
Two-hybrid Homo sapiens
425 DDX19B 11269
Affinity Capture-MS Homo sapiens
426 VEZT 55591
Proximity Label-MS Homo sapiens
427 EMD 2010
Proximity Label-MS Homo sapiens
428 STEAP3 55240
Proximity Label-MS Homo sapiens
429 RTN1 6252
Proximity Label-MS Homo sapiens
430 HIVEP1 3096
Affinity Capture-MS Homo sapiens
431 HTT 3064
Proximity Label-MS Homo sapiens
432 SCAMP1 9522
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
433 PIK3CB 5291
Affinity Capture-MS Homo sapiens
434 TAF12  
Affinity Capture-MS Homo sapiens
435 SCAMP2 10066
Affinity Capture-MS Homo sapiens
436 CENPM  
Affinity Capture-MS Homo sapiens
437 FAM135A  
Proximity Label-MS Homo sapiens
438 PI4KB 5298
Proximity Label-MS Homo sapiens
439 MIA3 375056
Proximity Label-MS Homo sapiens
440 SLC7A2 6542
Proximity Label-MS Homo sapiens
441 MOGS 7841
Co-fractionation Homo sapiens
442 STX6 10228
Proximity Label-MS Homo sapiens
443 COG3 83548
Proximity Label-MS Homo sapiens
444 RAB11FIP5 26056
Proximity Label-MS Homo sapiens
445 RHOT2 89941
Co-fractionation Homo sapiens
446 ACBD3 64746
Proximity Label-MS Homo sapiens
447 SNAP29 9342
Proximity Label-MS Homo sapiens
448 TEX2 55852
Proximity Label-MS Homo sapiens
449 NEURL4  
Affinity Capture-Western Homo sapiens
450 SNX1 6642
Proximity Label-MS Homo sapiens
451 SEC63 11231
Proximity Label-MS Homo sapiens
452 CACHD1  
Proximity Label-MS Homo sapiens
453 GOLGA3 2802
Proximity Label-MS Homo sapiens
454 RABGGTA 5875
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
455 VAPB 9217
Proximity Label-MS Homo sapiens
456 TCL1A  
Affinity Capture-Western Homo sapiens
457 CDKAL1  
Proximity Label-MS Homo sapiens
458 ATP2B1 490
Proximity Label-MS Homo sapiens
459 SLC20A2 6575
Proximity Label-MS Homo sapiens
460 RIN2  
Two-hybrid Homo sapiens
461 UQCRC2 7385
Co-fractionation Homo sapiens
462 HMOX2 3163
Proximity Label-MS Homo sapiens
463 ARF1 375
Co-fractionation Homo sapiens
464 SLC7A5 8140
Proximity Label-MS Homo sapiens
465 KCNN3  
Affinity Capture-Western Homo sapiens
466 EHBP1 23301
Proximity Label-MS Homo sapiens
467 GDI2 2665
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
468 KIRREL 55243
Proximity Label-MS Homo sapiens
469 ACSL3 2181
Proximity Label-MS Homo sapiens
470 MYO6 4646
Proximity Label-MS Homo sapiens
471 RAB2B 84932
Affinity Capture-MS Homo sapiens
472 ZFYVE21  
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
473 PPFIBP1 8496
Proximity Label-MS Homo sapiens
474 FNDC3A 22862
Proximity Label-MS Homo sapiens
475 STBD1 8987
Proximity Label-MS Homo sapiens
476 VDAC1 7416
Co-fractionation Homo sapiens
477 INPP5B 3633
Proximity Label-MS Homo sapiens
478 STX10 8677
Proximity Label-MS Homo sapiens
479 FSCN1 6624
Affinity Capture-MS Homo sapiens
480 ATG2B 55102
Proximity Label-MS Homo sapiens
481 DMXL1 1657
Proximity Label-MS Homo sapiens
482 SEC24B 10427
Proximity Label-MS Homo sapiens
483 SNCA 6622
Affinity Capture-Western Homo sapiens
484 KIAA1549  
Proximity Label-MS Homo sapiens
485 ANKFY1 51479
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
486 RRBP1 6238
Proximity Label-MS Homo sapiens
487 SLMAP 7871
Proximity Label-MS Homo sapiens
488 UBXN4 23190
Proximity Label-MS Homo sapiens
489 EHD4 30844
Proximity Label-MS Homo sapiens
490 SYAP1 94056
Proximity Label-MS Homo sapiens
491 RAB1B 81876
Co-fractionation Homo sapiens
492 DOPEY2 9980
Proximity Label-MS Homo sapiens
493 ELAVL1 1994
Affinity Capture-RNA Homo sapiens
494 NISCH 11188
Proximity Label-MS Homo sapiens
495 RAB1A 5861
Co-fractionation Homo sapiens
496 ROR2 4920
Proximity Label-MS Homo sapiens
497 UBIAD1 29914
Proximity Label-MS Homo sapiens
498 FAM160A1  
Proximity Label-MS Homo sapiens
499 CLMN  
Proximity Label-MS Homo sapiens
500 MOV10 4343
Co-fractionation Homo sapiens
501 SLC38A1 81539
Proximity Label-MS Homo sapiens
502 SLC6A8 6535
Proximity Label-MS Homo sapiens
503 CDK5RAP3 80279
Proximity Label-MS Homo sapiens
504 CFTR 1080
Affinity Capture-Western Homo sapiens
505 ESYT1 23344
Proximity Label-MS Homo sapiens
506 DSG2 1829
Proximity Label-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here