Gene description for UHRF1BP1
Gene name UHRF1 binding protein 1
Gene symbol UHRF1BP1
Other names/aliases C6orf107
ICBP90
dJ349A12.1
Species Homo sapiens
 Database cross references - UHRF1BP1
ExoCarta ExoCarta_54887
Vesiclepedia VP_54887
Entrez Gene 54887
HGNC 21216
UniProt Q6BDS2  
 UHRF1BP1 identified in exosomes derived from the following tissue/cell type
Endothelial cells 26027894    
 Gene ontology annotations for UHRF1BP1
Molecular Function
    protein binding GO:0005515 IPI
    identical protein binding GO:0042802 IPI
    histone deacetylase binding GO:0042826 IBA
    histone deacetylase binding GO:0042826 IPI
Subcellular Localization
    late endosome GO:0005770 IDA
 Experiment description of studies that identified UHRF1BP1 in exosomes
1
Experiment ID 226
MISEV standards
EM
Biophysical techniques
GAPDH|CD9|FLOT1
Enriched markers
LMNA|H2AFX|ATP5A1|TOMM20
Negative markers
Particle analysis
Identified molecule mRNA
Identification method Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
PubMed ID 26027894    
Organism Homo sapiens
Experiment description Quantitative and qualitative analysis of small RNAs in human endothelial cells and exosomes provides insights into localized RNA processing, degradation and sorting
Authors Bas W. M. van Balkom, Almut S. Eisele, D. Michiel Pegtel, Sander Bervoets, Marianne C. Verhaar
Journal name Journal of Extracellular Vesicles
Publication year 2015
Sample Endothelial cells
Sample name HMEC-1
Isolation/purification methods Differential ultracentrifugation
Sucrose density gradient
Flotation density 1.10 g/mL
Molecules identified in the study miRNA
Protein
snoRNA
lncRNA
yRNA
snRNA
mRNA
ncRNA
mtRNA
vtRNA
scaRNA
lincRNA
Methods used in the study Small RNA sequencing (Illumina HiSeq 2000 (Solexa)
Western blotting
 Protein-protein interactions for UHRF1BP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ZNF644  
Affinity Capture-MS Homo sapiens
2 CALML3 810
Affinity Capture-MS Homo sapiens
3 RAB9A 9367
Proximity Label-MS Homo sapiens
Affinity Capture-MS Homo sapiens
4 HNRNPD 3184
Affinity Capture-MS Homo sapiens
5 FAM131B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 RAB35 11021
Proximity Label-MS Homo sapiens
7 STK16 8576
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 LINC01587  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 LAMTOR1 55004
Proximity Label-MS Homo sapiens
10 UQCC2  
Affinity Capture-MS Homo sapiens
11 CREB3L3  
Affinity Capture-MS Homo sapiens
12 Tmed10 68581
Affinity Capture-MS Mus musculus
13 BAG6 7917
Affinity Capture-MS Homo sapiens
14 LAMP3  
Proximity Label-MS Homo sapiens
15 RAB5A 5868
Proximity Label-MS Homo sapiens
16 RAB11A 8766
Proximity Label-MS Homo sapiens
17 DNMT1 1786
Affinity Capture-MS Homo sapiens
18 EPB41L5 57669
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 MEF2BNB  
Affinity Capture-MS Homo sapiens
20 TSG101 7251
Affinity Capture-MS Homo sapiens
21 ATG9A 79065
Proximity Label-MS Homo sapiens
22 LAMP2 3920
Proximity Label-MS Homo sapiens
23 USP11 8237
Affinity Capture-MS Homo sapiens
24 RAB14 51552
Affinity Capture-MS Homo sapiens
25 CALM1 801
Affinity Capture-MS Homo sapiens
26 CBY1  
Affinity Capture-MS Homo sapiens
27 CREB3L1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 SSH3 54961
Affinity Capture-MS Homo sapiens
29 PCNA 5111
Affinity Capture-MS Homo sapiens
30 RAB4A 5867
Proximity Label-MS Homo sapiens
31 SGTB  
Affinity Capture-MS Homo sapiens
32 RPA3 6119
Proximity Label-MS Homo sapiens
33 DNAJC5 80331
Proximity Label-MS Homo sapiens
34 WDR5 11091
Affinity Capture-MS Homo sapiens
35 RAB30 27314
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 FIS1 51024
Affinity Capture-MS Homo sapiens
37 RPA4  
Proximity Label-MS Homo sapiens
38 RAPGEF2 9693
Affinity Capture-MS Homo sapiens
39 SLC7A6 9057
Affinity Capture-MS Homo sapiens
40 DIO3  
Affinity Capture-MS Homo sapiens
41 NPAS1  
Affinity Capture-MS Homo sapiens
42 NEDD1 121441
Affinity Capture-MS Homo sapiens
43 FOXK2  
Affinity Capture-MS Homo sapiens
44 RASEF  
Affinity Capture-MS Homo sapiens
45 Tube1  
Affinity Capture-MS Mus musculus
46 GOLGA1  
Proximity Label-MS Homo sapiens
47 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
48 RPA2 6118
Proximity Label-MS Homo sapiens
49 ALDH3B1 221
Affinity Capture-MS Homo sapiens
50 RAB3B 5865
Proximity Label-MS Homo sapiens
51 RAB7A 7879
Proximity Label-MS Homo sapiens
52 CREB3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 ACTL6B  
Affinity Capture-MS Homo sapiens
54 UHRF1 29128
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
55 KRT2 3849
Affinity Capture-MS Homo sapiens
56 MMP24 10893
Affinity Capture-MS Homo sapiens
57 CEP76  
Affinity Capture-MS Homo sapiens
58 Ufl1  
Affinity Capture-MS Mus musculus
59 HMG20A  
Affinity Capture-MS Homo sapiens
60 Bcl7c  
Affinity Capture-MS Mus musculus
61 FOXK1 221937
Affinity Capture-MS Homo sapiens
62 DEF8  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 STX6 10228
Proximity Label-MS Homo sapiens
64 GDAP2 54834
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which UHRF1BP1 is involved
No pathways found





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