Gene description for WDR5
Gene name WD repeat domain 5
Gene symbol WDR5
Other names/aliases BIG-3
CFAP89
SWD3
Species Homo sapiens
 Database cross references - WDR5
ExoCarta ExoCarta_11091
Vesiclepedia VP_11091
Entrez Gene 11091
HGNC 12757
MIM 609012
UniProt P61964  
 WDR5 identified in sEVs derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 23161513    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Mesenchymal stem cells 36408942    
Thymus 23844026    
 Gene ontology annotations for WDR5
Molecular Function
    protein binding GO:0005515 IPI
    methylated histone binding GO:0035064 IDA
    histone binding GO:0042393 IBA
    histone H3K4 methyltransferase activity GO:0042800 IEA
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IDA
    skeletal system development GO:0001501 IEA
    gluconeogenesis GO:0006094 IEA
    regulation of DNA-templated transcription GO:0006355 IMP
    regulation of DNA-templated transcription GO:0006355 ISS
    regulation of transcription by RNA polymerase II GO:0006357 IDA
    regulation of transcription by RNA polymerase II GO:0006357 ISS
    positive regulation of gluconeogenesis GO:0045722 IEA
    transcription initiation-coupled chromatin remodeling GO:0045815 IDA
    positive regulation of DNA-templated transcription GO:0045893 NAS
    regulation of embryonic development GO:0045995 ISO
    regulation of embryonic development GO:0045995 ISS
    regulation of cell division GO:0051302 IDA
    regulation of cell division GO:0051302 ISS
    regulation of cell cycle GO:0051726 IMP
    regulation of cell cycle GO:0051726 ISS
    regulation of tubulin deacetylation GO:0090043 IMP
    regulation of tubulin deacetylation GO:0090043 ISS
Subcellular Localization
    histone acetyltransferase complex GO:0000123 IDA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    nucleoplasm GO:0005654 TAS
    histone methyltransferase complex GO:0035097 IDA
    NSL complex GO:0044545 IDA
    MLL1/2 complex GO:0044665 IPI
    MLL3/4 complex GO:0044666 IDA
    MLL3/4 complex GO:0044666 IPI
    Set1C/COMPASS complex GO:0048188 IBA
    Set1C/COMPASS complex GO:0048188 IDA
    Set1C/COMPASS complex GO:0048188 IPI
    MLL1 complex GO:0071339 IDA
    MLL1 complex GO:0071339 IPI
    mitotic spindle GO:0072686 NAS
    ATAC complex GO:0140672 IDA
    ATAC complex GO:0140672 ISO
 Experiment description of studies that identified WDR5 in sEVs
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 207
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DKO-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
6
Experiment ID 208
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name Dks-8
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
7
Experiment ID 209
MISEV standards
✘ Biophysical techniques
✔
TSG101|HSP70|FLOT1
Enriched markers
✔
VDAC
Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23161513    
Organism Homo sapiens
Experiment description Proteomic analysis of exosomes from mutant KRAS colon cancer cells identifies intercellular transfer of mutant KRAS.
Authors "Demory Beckler M, Higginbotham JN, Franklin JL, Ham AJ, Halvey PJ, Imasuen IE, Whitwell C, Li M, Liebler DC, Coffey RJ."
Journal name Mol Cell Proteomics
Publication year 2012
Sample Colorectal cancer cells
Sample name DLD-1
Isolation/purification methods Differential centrifugation
Filtration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
9
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
10
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
11
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
12
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
13
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
14
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
15
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for WDR5
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HNRNPH1 3187
Affinity Capture-RNA Homo sapiens
2 MCRS1  
Affinity Capture-MS Homo sapiens
3 ATP6V1B2 526
Co-fractionation Homo sapiens
4 VPS35 55737
Co-fractionation Homo sapiens
5 UBE2H 7328
Affinity Capture-MS Homo sapiens
6 NCOA6  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
7 SENP3 26168
Affinity Capture-Western Homo sapiens
8 CBX1 10951
Affinity Capture-MS Homo sapiens
9 PPP1CB 5500
Co-fractionation Homo sapiens
10 KMT2C 58508
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
11 HDAC2 3066
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
12 PITX2  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
13 Set 56086
Affinity Capture-MS Mus musculus
14 DLC1 10395
Co-localization Homo sapiens
15 PAXIP1  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
16 SETBP1  
Affinity Capture-Western Homo sapiens
17 RPA2 6118
Proximity Label-MS Homo sapiens
18 SBF1 6305
Affinity Capture-MS Homo sapiens
19 BBC3  
Two-hybrid Homo sapiens
20 ZXDC  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
21 MTOR 2475
Affinity Capture-Western Homo sapiens
22 SRPK2 6733
Biochemical Activity Homo sapiens
23 RACGAP1 29127
Affinity Capture-Western Homo sapiens
24 BTF3 689
Affinity Capture-MS Homo sapiens
25 PPP1R3F  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
26 RPL37A 6168
Affinity Capture-MS Homo sapiens
27 ZNF608  
Affinity Capture-MS Homo sapiens
28 DPY30 84661
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
29 MAP4 4134
Co-fractionation Homo sapiens
30 HSPA4 3308
Co-fractionation Homo sapiens
31 ZZZ3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 UBC 7316
Affinity Capture-MS Homo sapiens
33 KDM6A  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
34 S100A2 6273
Co-fractionation Homo sapiens
35 TERF2IP 54386
Two-hybrid Homo sapiens
36 KANSL3  
Affinity Capture-MS Homo sapiens
37 WDR26 80232
Affinity Capture-Western Homo sapiens
38 SOX2  
Proximity Label-MS Homo sapiens
39 ARNTL  
Two-hybrid Homo sapiens
Affinity Capture-Luminescence Homo sapiens
40 CLSPN  
Affinity Capture-MS Homo sapiens
41 HSPA5 3309
Co-fractionation Homo sapiens
42 HSF2  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
43 HDAC1 3065
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
44 LRPPRC 10128
Co-fractionation Homo sapiens
45 E2F6 1876
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 PSIP1 11168
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
47 CAPZB 832
Affinity Capture-MS Homo sapiens
48 SAP30 8819
Co-fractionation Homo sapiens
49 TSG101 7251
Affinity Capture-Western Homo sapiens
50 MBIP  
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 ARHGEF2 9181
Affinity Capture-MS Homo sapiens
52 KDM5A  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
53 MDM4  
Two-hybrid Homo sapiens
54 TGFB1 7040
Affinity Capture-MS Homo sapiens
55 KIF23 9493
Affinity Capture-Western Homo sapiens
56 UHRF1BP1 54887
Affinity Capture-MS Homo sapiens
57 SPAG9 9043
Co-fractionation Homo sapiens
58 KDM2A  
Affinity Capture-MS Homo sapiens
59 COPS5 10987
Affinity Capture-MS Homo sapiens
60 FBXW7  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
61 PRC1 9055
Affinity Capture-Western Homo sapiens
62 IQGAP1 8826
Co-fractionation Homo sapiens
63 TBP  
Affinity Capture-MS Homo sapiens
64 KMT2D 8085
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
65 POU5F1  
Affinity Capture-Western Homo sapiens
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
66 WDR12 55759
Affinity Capture-Western Homo sapiens
67 POLR1E  
Proximity Label-MS Homo sapiens
68 AUTS2  
Affinity Capture-MS Homo sapiens
69 BOD1L1 259282
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
70 MYCN  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
71 PAGR1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
72 BDNF-AS  
Protein-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
73 HELLS 3070
Co-fractionation Homo sapiens
74 L3mbtl2  
Affinity Capture-MS Mus musculus
75 BMI1  
Affinity Capture-MS Homo sapiens
76 GRWD1 83743
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
77 BRD4 23476
Affinity Capture-Western Homo sapiens
78 SLX4  
Affinity Capture-MS Homo sapiens
79 KIF2C 11004
Co-fractionation Homo sapiens
80 ASH2L 9070
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 MLST8 64223
Affinity Capture-Western Homo sapiens
82 TAF1  
Affinity Capture-MS Homo sapiens
83 MAVS 57506
Affinity Capture-Western Homo sapiens
84 CUL1 8454
Affinity Capture-MS Homo sapiens
85 RUSC1-AS1  
Two-hybrid Homo sapiens
86 SETD1A 9739
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 NR2E3  
Two-hybrid Homo sapiens
88 MLLT1 4298
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
89 CSNK2B 1460
Affinity Capture-MS Homo sapiens
90 PLS3 5358
Co-fractionation Homo sapiens
91 YAF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
92 MTA2 9219
Co-fractionation Homo sapiens
93 GSPT1 2935
Co-fractionation Homo sapiens
94 HMGA1 3159
Affinity Capture-MS Homo sapiens
95 PRNP 5621
Reconstituted Complex Homo sapiens
96 ADSL 158
Co-fractionation Homo sapiens
97 Paxip1  
Affinity Capture-MS Mus musculus
98 AHCY 191
Co-fractionation Homo sapiens
99 KANSL1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
100 GTF2I 2969
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
101 UNC45A 55898
Co-fractionation Homo sapiens
102 E2F4  
Affinity Capture-MS Homo sapiens
103 H2AFZ 3015
Affinity Capture-MS Homo sapiens
104 CXXC1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
105 UFL1 23376
Affinity Capture-MS Homo sapiens
106 PDE9A  
Two-hybrid Homo sapiens
107 PHF20L1  
Affinity Capture-MS Homo sapiens
108 MOXD1 26002
Affinity Capture-Western Homo sapiens
109 TCP1 6950
Co-fractionation Homo sapiens
110 UBR5 51366
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
111 FOXA1  
Affinity Capture-MS Homo sapiens
112 BHLHE41  
Two-hybrid Homo sapiens
113 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
114 CEP55 55165
Affinity Capture-Western Homo sapiens
115 TLX3  
Proximity Label-MS Homo sapiens
116 ECT2 1894
Affinity Capture-Western Homo sapiens
117 HCFC2  
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
118 TADA3  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
119 CUL4B 8450
Affinity Capture-Western Homo sapiens
120 WWP2 11060
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
121 CEBPE  
Co-localization Homo sapiens
122 HIST4H4 121504
Biochemical Activity Homo sapiens
123 HELB  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
124 WDR53  
Affinity Capture-Western Homo sapiens
125 LRIF1  
Affinity Capture-MS Homo sapiens
126 CHMP1B 57132
Affinity Capture-Western Homo sapiens
127 ZBTB48  
Two-hybrid Homo sapiens
128 CBX3 11335
Affinity Capture-MS Homo sapiens
129 WDR61 80349
Affinity Capture-Western Homo sapiens
130 TFDP1  
Affinity Capture-MS Homo sapiens
131 PTPN21 11099
Affinity Capture-MS Homo sapiens
132 KDM4B  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
133 CARM1 10498
Affinity Capture-Western Homo sapiens
134 TAF4 6874
Co-fractionation Homo sapiens
135 YAP1 10413
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
136 MYH9 4627
Co-fractionation Homo sapiens
137 BARD1 580
Affinity Capture-MS Homo sapiens
138 NTRK1 4914
Affinity Capture-MS Homo sapiens
139 PSMC5 5705
Co-localization Homo sapiens
140 PABPC1 26986
Co-fractionation Homo sapiens
141 U2AF2 11338
Co-fractionation Homo sapiens
142 MEOX2  
Two-hybrid Homo sapiens
143 PKN1 5585
Co-localization Homo sapiens
144 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
145 Bod1  
Affinity Capture-MS Mus musculus
146 CCDC101  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
147 CSNK1E 1454
Affinity Capture-MS Homo sapiens
148 SRY  
Affinity Capture-Western Homo sapiens
149 FGFRL1 53834
Co-localization Homo sapiens
150 HECTD1 25831
Affinity Capture-MS Homo sapiens
151 UTY  
Affinity Capture-MS Homo sapiens
152 IARS 3376
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
153 L3MBTL2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
154 HOTTIP  
Protein-RNA Homo sapiens
Affinity Capture-RNA Homo sapiens
155 ITGB2 3689
Co-localization Homo sapiens
156 HDAC5 10014
Affinity Capture-MS Homo sapiens
157 KLF12  
Proximity Label-MS Homo sapiens
158 DNM1L 10059
Co-fractionation Homo sapiens
159 RYBP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
160 HIST2H2BE 8349
Affinity Capture-MS Homo sapiens
161 SSX2IP  
Two-hybrid Homo sapiens
162 POLR2B 5431
Co-fractionation Homo sapiens
163 SP1  
Co-fractionation Homo sapiens
164 TWIST1  
Affinity Capture-Western Homo sapiens
165 WDR82 80335
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
166 RING1 6015
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
167 YEATS2  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
168 Ring1  
Affinity Capture-MS Mus musculus
169 DTL  
Affinity Capture-Western Homo sapiens
170 OGT 8473
Co-fractionation Homo sapiens
171 MTMR1 8776
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
172 PSMA3 5684
Affinity Capture-MS Homo sapiens
173 TRAF6 7189
Affinity Capture-Western Homo sapiens
174 HIST1H3A 8350
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Co-crystal Structure Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
175 KMT2A  
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-MS Homo sapiens
Protein-peptide Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
176 RERE 473
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
177 CIAO1 9391
Affinity Capture-Western Homo sapiens
178 XPO1 7514
Affinity Capture-MS Homo sapiens
179 SMARCA5 8467
Co-fractionation Homo sapiens
180 MGA  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
181 HCFC1 3054
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
182 FLT3  
Co-localization Homo sapiens
183 SRRM4  
Two-hybrid Homo sapiens
184 CUL3 8452
Affinity Capture-MS Homo sapiens
185 CSRP2BP  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
186 KLF3  
Proximity Label-MS Homo sapiens
187 ADNP 23394
Affinity Capture-MS Homo sapiens
188 YY1 7528
Proximity Label-MS Homo sapiens
189 KANSL2  
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Reconstituted Complex Homo sapiens
190 EPRS 2058
Affinity Capture-MS Homo sapiens
191 PDPK1 5170
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
Reconstituted Complex Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-crystal Structure Homo sapiens
192 Wdr82  
Affinity Capture-MS Mus musculus
193 TRAF3 7187
Affinity Capture-Western Homo sapiens
194 HIST3H3 8290
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
Biochemical Activity Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
195 KIAA0430  
Two-hybrid Homo sapiens
196 CAND1 55832
Affinity Capture-MS Homo sapiens
197 HNF4A  
Proximity Label-MS Homo sapiens
198 PRMT5 10419
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
199 PSMA4 5685
Co-fractionation Homo sapiens
200 SESN2 83667
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
201 TADA2A  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
202 MYC  
Affinity Capture-Western Homo sapiens
Proximity Label-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
203 CEBPB  
Affinity Capture-Western Homo sapiens
204 EIF2D 1939
Co-fractionation Homo sapiens
205 MSL1 339287
Affinity Capture-MS Homo sapiens
206 INO80B 83444
Affinity Capture-MS Homo sapiens
207 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
208 MAPKAP1 79109
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
209 INO80  
Affinity Capture-MS Homo sapiens
210 PIK3CA 5290
Affinity Capture-MS Homo sapiens
211 ACTB 60
Affinity Capture-MS Homo sapiens
212 HIST1H1A 3024
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
213 SAC3D1  
Co-fractionation Homo sapiens
214 SNW1 22938
Affinity Capture-MS Homo sapiens
215 CHD8 57680
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
216 KAT8  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
217 RNF2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 ATN1  
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
219 IQSEC1 9922
Affinity Capture-MS Homo sapiens
220 PML 5371
Affinity Capture-MS Homo sapiens
221 Cxxc1  
Affinity Capture-MS Mus musculus
222 MAP3K7  
Co-fractionation Homo sapiens
223 PYGO2  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
224 RBBP5 5929
Co-purification Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Co-crystal Structure Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
225 MYB  
Affinity Capture-Western Homo sapiens
226 ZNF462  
Affinity Capture-MS Homo sapiens
227 PASK  
Affinity Capture-MS Homo sapiens
228 RICTOR 253260
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
229 CHD7  
Co-localization Homo sapiens
230 APP 351
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
231 LCN2 3934
Co-localization Homo sapiens
232 PAFAH1B1 5048
Affinity Capture-Western Homo sapiens
233 KRT18 3875
Co-fractionation Homo sapiens
234 TAF6 6878
Co-fractionation Homo sapiens
235 SPECC1 92521
Affinity Capture-MS Homo sapiens
236 KIF2A 3796
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
237 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
238 PHF20  
Affinity Capture-MS Homo sapiens
239 TERF2  
Affinity Capture-MS Homo sapiens
240 MAX  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
241 KAT2A  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
242 HDGF 3068
Affinity Capture-MS Homo sapiens
243 TROVE2 6738
Co-fractionation Homo sapiens
244 TP53 7157
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
245 MBD3 53615
Co-fractionation Homo sapiens
246 NLE1 54475
Affinity Capture-Western Homo sapiens
247 HSPA8 3312
Co-fractionation Homo sapiens
248 RFWD2  
Affinity Capture-Western Homo sapiens
249 KMT2B  
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
250 KDM1B  
Affinity Capture-MS Homo sapiens
251 BOD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
252 USP36  
Affinity Capture-MS Homo sapiens
253 FAM199X 139231
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
254 MEN1 4221
Co-purification Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
255 USP1 7398
Co-fractionation Homo sapiens
256 IKBKG 8517
Reconstituted Complex Homo sapiens
257 AGMAT  
Affinity Capture-MS Homo sapiens
258 LIF 3976
Co-localization Homo sapiens
259 SLC7A6OS  
Affinity Capture-MS Homo sapiens
260 ZC2HC1A 51101
Affinity Capture-MS Homo sapiens
261 ZNF335 63925
Affinity Capture-Western Homo sapiens
262 ZBTB2 57621
Affinity Capture-MS Homo sapiens
263 CREBBP  
Affinity Capture-Western Homo sapiens
264 MEIS2  
Co-localization Homo sapiens
265 TTK 7272
Co-fractionation Homo sapiens
266 HSP90AA1 3320
Co-fractionation Homo sapiens
267 PDCD6IP 10015
Affinity Capture-Western Homo sapiens
268 BUB3 9184
Affinity Capture-MS Homo sapiens
269 KDM6B 23135
Affinity Capture-Western Homo sapiens
270 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
271 SETD1B 23067
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Co-crystal Structure Homo sapiens
Protein-peptide Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
272 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
273 CSE1L 1434
Co-fractionation Homo sapiens
274 ESR1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
275 ANAPC2 29882
Two-hybrid Homo sapiens
276 Kat8  
Affinity Capture-MS Mus musculus
Affinity Capture-MS Mus musculus
277 PWP1 11137
Affinity Capture-MS Homo sapiens
278 NFE4  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
279 SNRNP40 9410
Affinity Capture-Western Homo sapiens
280 PAX7  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
281 KDM1A 23028
Co-fractionation Homo sapiens
282 HDAC3 8841
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
283 GAPDH 2597
Co-fractionation Homo sapiens
284 PSMA7 5688
Co-fractionation Homo sapiens
285 CYLD  
Affinity Capture-MS Homo sapiens
286 PCGF6  
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
287 HARS 3035
Co-fractionation Homo sapiens
288 CIT 11113
Affinity Capture-MS Homo sapiens
289 KAT2B  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
290 WDR59 79726
Affinity Capture-Western Homo sapiens
291 SERBP1 26135
Co-fractionation Homo sapiens
292 WDR5B  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
293 KAT6A  
Affinity Capture-Western Homo sapiens
294 RARS 5917
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
295 AR 367
Proximity Label-MS Homo sapiens
296 USF1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
297 NUCKS1 64710
Affinity Capture-MS Homo sapiens
298 SAP18 10284
Co-fractionation Homo sapiens
299 PHF8  
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
300 RPA3 6119
Proximity Label-MS Homo sapiens
301 ING2  
Affinity Capture-Western Homo sapiens
302 DR1  
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
303 DDRGK1 65992
Affinity Capture-MS Homo sapiens
304 CUL4A 8451
Affinity Capture-Western Homo sapiens
305 EP300 2033
Affinity Capture-Western Homo sapiens
306 PSMD3 5709
Co-fractionation Homo sapiens
307 EGR2  
Co-localization Homo sapiens
View the network image/svg+xml
 Pathways in which WDR5 is involved
PathwayEvidenceSource
Activation of anterior HOX genes in hindbrain development during early embryogenesis IEA Reactome
Activation of HOX genes during differentiation IEA Reactome
Cardiogenesis IEA Reactome
Chromatin modifying enzymes TAS Reactome
Chromatin modifying enzymes IEA Reactome
Chromatin organization TAS Reactome
Chromatin organization IEA Reactome
Developmental Biology IEA Reactome
Epigenetic regulation by WDR5-containing histone modifying complexes TAS Reactome
Epigenetic regulation by WDR5-containing histone modifying complexes IEA Reactome
Epigenetic regulation of adipogenesis genes by MLL3 and MLL4 complexes IEA Reactome
Epigenetic regulation of gene expression TAS Reactome
Epigenetic regulation of gene expression IEA Reactome
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes TAS Reactome
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes IEA Reactome
Formation of WDR5-containing histone-modifying complexes TAS Reactome
Gene expression (Transcription) TAS Reactome
Gene expression (Transcription) IEA Reactome
Generic Transcription Pathway TAS Reactome
HATs acetylate histones IEA Reactome
HATs acetylate histones TAS Reactome
Metabolism of proteins TAS Reactome
MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis IEA Reactome
Neddylation TAS Reactome
PKMTs methylate histone lysines TAS Reactome
Post-translational protein modification TAS Reactome
RMTs methylate histone arginines TAS Reactome
RNA Polymerase II Transcription TAS Reactome
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function TAS Reactome
Transcriptional regulation by RUNX1 TAS Reactome





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