Gene description for KDM6B
Gene name	lysine (K)-specific demethylase 6B
Gene symbol	KDM6B
Other names/aliases	JMJD3
Species	Homo sapiens
Database cross references - KDM6B
ExoCarta	ExoCarta_23135
Vesiclepedia	VP_23135
Entrez Gene	23135
HGNC	29012
MIM	611577
UniProt	O15054
KDM6B identified in exosomes derived from the following tissue/cell type
Neuroblastoma cells	25944692
Thymus	23844026

Gene ontology annotations for KDM6B

Molecular Function     RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0000978 IBA     protein binding GO:0005515 IPI     beta-catenin binding GO:0008013 IEA     chromatin DNA binding GO:0031490 IBA     histone demethylase activity GO:0032452 TAS     metal ion binding GO:0046872 IEA     histone H3K27me2/H3K27me3 demethylase activity GO:0071558 IBA     histone H3K27me2/H3K27me3 demethylase activity GO:0071558 IMP Biological Process     inflammatory response to antigenic stimulus GO:0002437 IEA     chromatin remodeling GO:0006338 ISS     heart development GO:0007507 IBA     regulation of gene expression GO:0010468 IBA     response to activity GO:0014823 IEA     hippocampus development GO:0021766 IEA     cell fate commitment GO:0045165 IEA     endothelial cell differentiation GO:0045446 ISS     positive regulation of transcription by RNA polymerase II GO:0045944 ISS     mesodermal cell differentiation GO:0048333 ISS     cardiac muscle cell differentiation GO:0055007 ISS     response to fungicide GO:0060992 IEA     cellular response to hydrogen peroxide GO:0070301 IEA     positive regulation of cold-induced thermogenesis GO:0120162 ISS Subcellular Localization     nucleus GO:0005634 ISS     nucleoplasm GO:0005654 TAS     MLL3/4 complex GO:0044666 IBA