Gene description for WAS
Gene name	Wiskott-Aldrich syndrome
Gene symbol	WAS
Other names/aliases	IMD2 SCNX THC THC1 WASP WASPA
Species	Homo sapiens
Database cross references - WAS
ExoCarta	ExoCarta_7454
Entrez Gene	7454
HGNC	12731
MIM	300392
UniProt	P42768
WAS identified in exosomes derived from the following tissue/cell type
B cells	20458337
B cells	20458337
B cells	20458337
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for WAS

Molecular Function     identical protein binding GO:0042802 IPI     protein kinase binding GO:0019901 IPI     protein binding GO:0005515 IPI     actin binding GO:0003779 IEA     SH3 domain binding GO:0017124 IPI     GTPase regulator activity GO:0030695 TAS     phospholipase binding GO:0043274 IPI Biological Process     epidermis development GO:0008544 TAS     regulation of catalytic activity GO:0050790 TAS     regulation of T cell antigen processing and presentation GO:0002625 IMP     negative regulation of cell motility GO:2000146 IMP     actin polymerization or depolymerization GO:0008154 TAS     endosomal transport GO:0016197 IEA     immune response GO:0006955 IMP     protein complex assembly GO:0006461 TAS     actin filament-based movement GO:0030048 IEA     actin filament polymerization GO:0030041 IEA     innate immune response GO:0045087 TAS     blood coagulation GO:0007596 TAS     T cell activation GO:0042110 IEA     Fc-gamma receptor signaling pathway involved in phagocytosis GO:0038096 TAS     small GTPase mediated signal transduction GO:0007264 TAS     T cell receptor signaling pathway GO:0050852 TAS     defense response GO:0006952 TAS     positive regulation of Arp2/3 complex-mediated actin nucleation GO:2000601 IEA Subcellular Localization     cytosol GO:0005829 TAS     extracellular exosome GO:0070062 IDA     cell-cell junction GO:0005911 IEA     actin cytoskeleton GO:0015629 TAS     vesicle membrane GO:0012506 IEA