Gene description for ITK
Gene name	IL2-inducible T-cell kinase
Gene symbol	ITK
Other names/aliases	EMT LPFS1 LYK PSCTK2
Species	Homo sapiens
Database cross references - ITK
ExoCarta	ExoCarta_3702
Entrez Gene	3702
HGNC	6171
MIM	186973
UniProt	Q08881
ITK identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for ITK

Molecular Function     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     metal ion binding GO:0046872 IEA     receptor binding GO:0005102 IBA     non-membrane spanning protein tyrosine kinase activity GO:0004715 IDA Biological Process     regulation of cell proliferation GO:0042127 IBA     cytokine production GO:0001816 ISS     Fc-epsilon receptor signaling pathway GO:0038095 TAS     adaptive immune response GO:0002250 ISS     innate immune response GO:0045087 TAS     activation of phospholipase C activity GO:0007202 ISS     T cell receptor signaling pathway GO:0050852 TAS     interleukin-4 production GO:0032633 IEA     signal transduction GO:0007165 TAS     interferon-gamma production GO:0032609 IEA     cellular defense response GO:0006968 TAS     T cell activation GO:0042110 TAS     NK T cell differentiation GO:0001865 IBA     intracellular signal transduction GO:0035556 IEA     peptidyl-tyrosine autophosphorylation GO:0038083 IBA     B cell receptor signaling pathway GO:0050853 IBA     transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 IBA Subcellular Localization     extrinsic component of cytoplasmic side of plasma membrane GO:0031234 IBA     cell-cell junction GO:0005911 IEA     cytosol GO:0005829 TAS