Experiment description of studies that identified Mbp in exosomes

1 Experiment ID 33 MISEV standards ✔ EM|IEM Biophysical techniques ✔ Alix|TSG101 Enriched markers ✘ Negative markers ✘ Particle analysis Identified molecule protein Identification method Mass spectrometry PubMed ID 21136642     Organism Mus musculus Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons? Authors Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J Journal name PROTEOMICS_CL Publication year 2007 Sample Oligodendrocytes Sample name Oligodendrocytes Oli-neu Isolation/purification methods Differential centrifugation Sucrose density gradient Flotation density 1.10-1.14 g/mL Molecules identified in the study Protein Methods used in the study Mass spectrometry [QTOF] Western blotting Immunoelectron Microscopy

Protein-protein interactions for Mbp

Protein Interactor ExoCarta ID Identification method PubMed Species 1 MPP2 4355 Protein-peptide Homo sapiens 2 RASA1 5921 Protein-peptide Homo sapiens 3 Ptpn6   Biochemical Activity Rattus norvegicus 4 PEX13   Protein-peptide Homo sapiens 5 VAV1 7409 Protein-peptide Homo sapiens 6 ABL2   Protein-peptide Homo sapiens 7 ARHGEF7 8874 Protein-peptide Homo sapiens 8 NCK1 4690 Protein-peptide Homo sapiens 9 Prnp 19122 Affinity Capture-MS Mus musculus 10 Aph1b   Affinity Capture-MS Mus musculus 11 Prkcz   Biochemical Activity Mus musculus 12 Kcnma1   Affinity Capture-MS Mus musculus 13 FYB 2533 Protein-peptide Homo sapiens 14 ABL1 25 Protein-peptide Homo sapiens 15 Kctd13   Affinity Capture-MS Mus musculus 16 LCK 3932 Protein-peptide Homo sapiens 17 PHEX   Protein-peptide Homo sapiens 18 NEB 4703 Protein-peptide Homo sapiens 19 CTTN 2017 Protein-peptide Homo sapiens 20 Htt   Affinity Capture-MS Mus musculus 21 CALM1 801 Affinity Capture-MS Homo sapiens 22 DLG4   Protein-peptide Homo sapiens 23 ATG1   Biochemical Activity 24 Lrrk2   Biochemical Activity Mus musculus 25 Srsf9   Two-hybrid Mus musculus 26 Ywhaz 22631 Affinity Capture-MS Mus musculus 27 Ilk 16202 Biochemical Activity Mus musculus 28 BLK 640 Protein-peptide Homo sapiens 29 Tmem173   Proximity Label-MS Mus musculus 30 YES1 7525 Protein-peptide Homo sapiens 31 MAP3K5 4217 Biochemical Activity Homo sapiens 32 MAPT   Reconstituted Complex Homo sapiens 33 Rock2   Co-fractionation Mus musculus 34 HCK 3055 Protein-peptide Homo sapiens 35 FYN 2534 Protein-peptide Homo sapiens 36 LRRK2 120892 Biochemical Activity Homo sapiens 37 Aph1a 226548 Affinity Capture-MS Mus musculus 38 ARHGEF5   Protein-peptide Homo sapiens 39 Mapk3 26417 Biochemical Activity Mus musculus Biochemical Activity Mus musculus 40 KRT31 3881 Two-hybrid Homo sapiens 41 Prkaca   Biochemical Activity Mus musculus 42 PIK3R2 5296 Protein-peptide Homo sapiens 43 SRC 6714 Protein-peptide Homo sapiens 44 ITK 3702 Protein-peptide Homo sapiens 45 BTK 695 Protein-peptide Homo sapiens 46 Mapk1 26413 Biochemical Activity Mus musculus Biochemical Activity Mus musculus 47 VAV2 7410 Protein-peptide Homo sapiens 48 TFIP11   Two-hybrid Homo sapiens 49 RBPMS 11030 Two-hybrid Homo sapiens 50 ITSN1 6453 Protein-peptide Homo sapiens 51 Ksr1   Biochemical Activity Mus musculus 52 Pak1   Biochemical Activity Mus musculus 53 EXOSC8   Two-hybrid Homo sapiens 54 HCLS1 3059 Protein-peptide Homo sapiens 55 STAM 8027 Protein-peptide Homo sapiens View the network

Pathways in which Mbp is involved

No pathways found