Gene description for RASA1
Gene name	RAS p21 protein activator (GTPase activating protein) 1
Gene symbol	RASA1
Other names/aliases	CM-AVM CMAVM GAP PKWS RASA RASGAP p120GAP p120RASGAP
Species	Homo sapiens
Database cross references - RASA1
ExoCarta	ExoCarta_5921
Entrez Gene	5921
HGNC	9871
MIM	139150
UniProt	P20936
RASA1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells	26054723
Mesenchymal stem cells	Unpublished / Not applicable
Platelets	25332113
Platelets	25332113
Platelets	25332113

Gene ontology annotations for RASA1

Molecular Function     protein binding GO:0005515 IPI     glycoprotein binding GO:0001948 IPI     GTPase binding GO:0051020 IPI     potassium channel inhibitor activity GO:0019870 NAS     GTPase activator activity GO:0005096 EXP     receptor binding GO:0005102 IPI Biological Process     negative regulation of cell adhesion GO:0007162 IDA     blood vessel morphogenesis GO:0048514 IMP     regulation of actin filament polymerization GO:0030833 IDA     axon guidance GO:0007411 TAS     ephrin receptor signaling pathway GO:0048013 TAS     vascular endothelial growth factor receptor signaling pathway GO:0048010 TAS     regulation of cell shape GO:0008360 NAS     negative regulation of neuron apoptotic process GO:0043524 ISS     negative regulation of cell-matrix adhesion GO:0001953 IDA     intracellular signal transduction GO:0035556 NAS     positive regulation of GTPase activity GO:0043547 TAS     embryo development GO:0009790 ISS     signal transduction GO:0007165 IDA     mitotic cytokinesis GO:0000281 ISS     negative regulation of Ras protein signal transduction GO:0046580 IBA     regulation of RNA metabolic process GO:0051252 NAS     vasculogenesis GO:0001570 ISS Subcellular Localization     ruffle GO:0001726 IEA     cytoplasm GO:0005737 NAS     intrinsic component of the cytoplasmic side of the plasma membrane GO:0031235 IBA     cytosol GO:0005829 TAS