Gene description for GNB2L1
Gene name guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
Gene symbol GNB2L1
Other names/aliases Gnb2-rs1
H12.3
HLC-7
PIG21
RACK1
Species Homo sapiens
 Database cross references - GNB2L1
ExoCarta ExoCarta_10399
Vesiclepedia VP_10399
Entrez Gene 10399
HGNC 4399
MIM 176981
UniProt P63244  
 GNB2L1 identified in sEVs derived from the following tissue/cell type
Bladder cancer cells 20224111    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Chondrocytes 35931686    
Colorectal cancer cells 17956143    
Colorectal cancer cells 19837982    
Colorectal cancer cells 22740476    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 25890246    
Colorectal cancer cells 34887515    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 36706192    
Embryonic kidney cells 36706192    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Gastric cancer cells 33991177    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocellular carcinoma cells 26054723    
Hepatocytes 26054723    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Melanoma cells 25950383    
Mesenchymal stem cells 36408942    
Neuroblastoma cells 25944692    
Ovarian cancer cells 23333927    
Ovarian cancer cells 23333927    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Thymus 23844026    
Urine 19056867    
 Gene ontology annotations for GNB2L1
Molecular Function
    RNA binding GO:0003723 HDA
    protein kinase C binding GO:0005080 IBA
    protein kinase C binding GO:0005080 IDA
    signaling receptor binding GO:0005102 NAS
    protein binding GO:0005515 IPI
    enzyme activator activity GO:0008047 IDA
    ion channel inhibitor activity GO:0008200 ISS
    cysteine-type endopeptidase activator activity involved in apoptotic process GO:0008656 IMP
    enzyme binding GO:0019899 IPI
    protein phosphatase binding GO:0019903 IPI
    protein tyrosine kinase inhibitor activity GO:0030292 IDA
    cyclin binding GO:0030332 IPI
    receptor tyrosine kinase binding GO:0030971 IDA
    signaling adaptor activity GO:0035591 IMP
    SH2 domain binding GO:0042169 IDA
    identical protein binding GO:0042802 IPI
    protein homodimerization activity GO:0042803 IPI
    ribosome binding GO:0043022 IBA
    ribosome binding GO:0043022 IDA
    translation regulator activity GO:0045182 IEA
    cadherin binding GO:0045296 HDA
    BH3 domain binding GO:0051434 IDA
    molecular adaptor activity GO:0060090 TAS
Biological Process
    positive regulation of protein phosphorylation GO:0001934 IDA
    cytoplasmic translation GO:0002181 NAS
    apoptotic process GO:0006915 IEA
    gastrulation GO:0007369 IEA
    negative regulation of gene expression GO:0010629 IMP
    protein ubiquitination GO:0016567 IMP
    negative regulation of translation GO:0017148 ISS
    negative regulation of Wnt signaling pathway GO:0030178 ISS
    negative regulation of cell growth GO:0030308 IDA
    positive regulation of cell migration GO:0030335 IDA
    positive regulation of protein-containing complex assembly GO:0031334 IDA
    negative regulation of protein binding GO:0032091 IDA
    positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032436 IDA
    regulation of protein localization GO:0032880 ISS
    negative regulation of peptidyl-serine phosphorylation GO:0033137 IMP
    positive regulation of Golgi to plasma membrane protein transport GO:0042998 IMP
    positive regulation of apoptotic process GO:0043065 IDA
    positive regulation of apoptotic process GO:0043065 IMP
    pigmentation GO:0043473 IEA
    positive regulation of GTPase activity GO:0043547 IDA
    negative regulation of smoothened signaling pathway GO:0045879 IDA
    rhythmic process GO:0048511 IEA
    negative regulation of phagocytosis GO:0050765 IMP
    regulation of cell division GO:0051302 ISS
    regulation of cell cycle GO:0051726 IDA
    negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051898 IMP
    positive regulation of mitochondrial depolarization GO:0051901 IMP
    cellular response to glucose stimulus GO:0071333 IDA
    cellular response to growth factor stimulus GO:0071363 IDA
    rescue of stalled ribosome GO:0072344 IBA
    rescue of stalled ribosome GO:0072344 IMP
    regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway GO:0106070 IMP
    negative regulation of endoplasmic reticulum unfolded protein response GO:1900102 TAS
    negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide GO:1903751 IGI
    regulation of establishment of cell polarity GO:2000114 ISS
    positive regulation of gastrulation GO:2000543 ISS
    positive regulation of cysteine-type endopeptidase activity GO:2001056 IMP
    negative regulation of translational frameshifting GO:2001125 IBA
    positive regulation of intrinsic apoptotic signaling pathway GO:2001244 IMP
Subcellular Localization
    phagocytic cup GO:0001891 IDA
    nucleus GO:0005634 IBA
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IDA
    cytoplasm GO:0005737 IDA
    cytoplasm GO:0005737 NAS
    mitochondrion GO:0005739 IMP
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 IMP
    cytosol GO:0005829 TAS
    small ribosomal subunit GO:0015935 ISS
    cytosolic small ribosomal subunit GO:0022627 NAS
    dendrite GO:0030425 ISS
    midbody GO:0030496 IDA
    neuronal cell body GO:0043025 ISS
    perikaryon GO:0043204 IEA
    perinuclear region of cytoplasm GO:0048471 IDA
    extracellular exosome GO:0070062 HDA
    IRE1-RACK1-PP2A complex GO:1990630 IDA
 Experiment description of studies that identified GNB2L1 in sEVs
1
Experiment ID 76
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|GAPDH|HSP90|CD81|CD9|CD63|LAMP1|MHCI
Enriched markers
✔
HSP90B1
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20224111    
Organism Homo sapiens
Experiment description Proteomics analysis of bladder cancer exosomes.
Authors "Welton JL, Khanna S, Giles PJ, Brennan P, Brewis IA, Staffurth J, Mason MD, Clayton A."
Journal name MCP
Publication year 2010
Sample Bladder cancer cells
Sample name HT1376
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [MALDI TOF/TOF]
Western blotting
FACS
2
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
5
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
6
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
8
Experiment ID 494
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD151|CD63|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Osteoarthritic cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
9
Experiment ID 496
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|SDCBP|TFRC|TSG101
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name Healthy cartilage
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
10
Experiment ID 497
MISEV standards
✘ Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
11
Experiment ID 498
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD151|CD63|CD81|CD82|FLOT1|FLOT2|GAPDH|LAMP1|LAMP2|RAB5A|SDCBP|TFRC|TSG101|UCHL1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 35931686    
Organism Homo sapiens
Experiment description Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression
Authors "Varela-Eirín M, Carpintero-Fernández P, Guitián-Caamaño A, Varela-Vázquez A, García-Yuste A, Sánchez-Temprano A, Bravo-López SB, Yañez-Cabanas J, Fonseca E, Largo R, Mobasheri A, Caeiro JR, Mayán MD."
Journal name Cell Death Dis
Publication year 2022
Sample Chondrocytes
Sample name T/C-28a2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
12
Experiment ID 20
MISEV standards
✔
EM
Biophysical techniques
✔
HSP90|CD63|CD81|LAMP1
Enriched markers
✔
GOLGA2|cytochrome c
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17956143    
Organism Homo sapiens
Experiment description Proteomic analysis of microvesicles derived from human colorectal cancer cells.
Authors "Choi DS, Lee JM, Park GW, Lim HW, Bang JY, Kim YK, Kwon KH, Kwon HJ, Kim KP, Gho YS"
Journal name JPR
Publication year 2007
Sample Colorectal cancer cells
Sample name HT29
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Diafiltration
Flotation density 1.16 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
13
Experiment ID 21
MISEV standards
✔
EM|IEM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method
Mass spectrometry   
PubMed ID 19837982    
Organism Homo sapiens
Experiment description Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215.
Authors "Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson"
Journal name MCP
Publication year 2009
Sample Colorectal cancer cells
Sample name LIM1215
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.10-1.12 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [Orbitrap]
Western blotting
14
Experiment ID 201
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 22740476    
Organism Homo sapiens
Experiment description Restoration of full-length APC protein in SW480 colon cancer cells induces exosome-mediated secretion of DKK-4.
Authors "Lim JW, Mathias RA, Kapp EA, Layton MJ, Faux MC, Burgess AW, Ji H, Simpson RJ."
Journal name Electrophoresis
Publication year 2012
Sample Colorectal cancer cells
Sample name SW480
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
15
Experiment ID 282
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
16
Experiment ID 283
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Ultracentrifugation - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
17
Experiment ID 285
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 1
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
18
Experiment ID 286
MISEV standards
✔
CEM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81|EpCAM
Enriched markers
✘ Negative markers
✔
DLS
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25890246    
Organism Homo sapiens
Experiment description Highly-purified exosomes and shed microvesicles isolated from the human colon cancer cell line LIM1863 by sequential centrifugal ultrafiltration are biochemically and functionally distinct.
Authors "Xu R, Greening DW, Rai A, Ji H, Simpson RJ."
Journal name Methods
Publication year 2015
Sample Colorectal cancer cells
Sample name LIM1863 - Sequential centrifugal ultrafiltration - Rep 2
Isolation/purification methods Differential centrifugation
Filtration
Sequential centrifugal ultrafiltration
Centrifugal concentration
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
19
Experiment ID 1203
MISEV standards
✔
EM
Biophysical techniques
✔
SDCBP|FLOT1|CD9|CD81|CD63|EPCAM|GAPDH|LAMP1|TFRC|CD151|CD82|LAMP2|RAB35|TSG101|FLOT2|RAB5B|ICAM1|RAB5A
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 34887515    
Organism Homo sapiens
Experiment description Supermeres are functional extracellular nanoparticles replete with disease biomarkers and therapeutic targets
Authors "Zhang Q, Jeppesen DK, Higginbotham JN, Graves-Deal R, Trinh VQ, Ramirez MA, Sohn Y, Neininger AC, Taneja N, McKinley ET, Niitsu H, Cao Z, Evans R, Glass SE, Ray KC, Fissell WH, Hill S, Rose KL, Huh WJ, Washington MK, Ayers GD, Burnette DT, Sharma S, Rome LH, Franklin JL, Lee YA, Liu Q, Coffey RJ."
Journal name Nat Cell Biol
Publication year 2021
Sample Colorectal cancer cells
Sample name DiFi
Isolation/purification methods Differential centrifugation
Filtration
Centrifugal ultrafiltration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
miRNA
Methods used in the study Western blotting
Mass spectrometry
RNA sequencing
20
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
21
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
22
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
23
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
24
Experiment ID 1275
MISEV standards
Biophysical techniques
✔
CD9|TSG101|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
25
Experiment ID 1280
MISEV standards
Biophysical techniques
✔
TSG101|CD9|FLOT1|FLOT2|RAB35|RAB5A|GAPDH|TFRC|CD63|Alix
Enriched markers
✔
PCNA|CANX|GAPDH|HSP90AA1|HSP90B1
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36706192    
Organism Homo sapiens
Experiment description Displaying and delivering viral membrane antigens via WW domain-activated extracellular vesicles
Authors "Choi S, Yang Z, Wang Q, Qiao Z, Sun M, Wiggins J, Xiang SH, Lu Q."
Journal name Sci Adv
Publication year 2023
Sample Embryonic kidney cells
Sample name HEK293T - Fraction 5
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density 1.151 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
26
Experiment ID 363
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
27
Experiment ID 364
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
28
Experiment ID 365
MISEV standards
✘ Biophysical techniques
✔
TSG101|GAPDH|AQP1|CD151|CD81|CD82|CD9|EPCAM|FLOT1|FLOT2|ICAM1|ITGA2B|LAMP2|RAB35|RAB5A|RAB5B|SDCBP|TFRC|UCHL1
Enriched markers
✔
DCLK1
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 33991177    
Organism Homo sapiens
Experiment description Cancer stem cell marker DCLK1 reprograms small extracellular vesicles toward migratory phenotype in gastric cancer cells
Authors "Carli ALE, Afshar-Sterle S, Rai A, Fang H, O'Keefe R, Tse J, Ferguson FM, Gray NS, Ernst M, Greening DW, Buchert M."
Journal name Proteomics
Publication year 2021
Sample Gastric cancer cells
Sample name MKN1 - 100K pellet
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
29
Experiment ID 234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-C3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
30
Experiment ID 235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name HKCI-8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
31
Experiment ID 236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
32
Experiment ID 237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors "He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
33
Experiment ID 254
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name MNT-1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
34
Experiment ID 255
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name G1
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
35
Experiment ID 256
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 501mel
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
36
Experiment ID 257
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name Daju
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
37
Experiment ID 258
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name SKMEL28
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
38
Experiment ID 259
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name A375M
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
39
Experiment ID 260
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|FLOT1|CD81
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25950383    
Organism Homo sapiens
Experiment description Proteome characterization of melanoma exosomes reveals a specific signature for metastatic cell lines
Authors "Lazar I, Clement E, Ducoux-Petit M, Denat L, Soldan V, Dauvillier S, Balor S4, Burlet-Schiltz O1, Larue L, Muller C Nieto L"
Journal name Pigment Cell Melanoma Res
Publication year 2015
Sample Melanoma cells
Sample name 1205Lu
Isolation/purification methods Differential centrifugation
Unltracentrifugation
Sucrose density gradient
Flotation density 1.13 - 1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
40
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
41
Experiment ID 224
MISEV standards
✔
EM|AFM
Biophysical techniques
✔
Alix|TSG101|CD63|CD81
Enriched markers
✔
GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
42
Experiment ID 211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name IGROV1
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
43
Experiment ID 212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23333927    
Organism Homo sapiens
Experiment description Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors "Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name J Proteomics
Publication year 2013
Sample Ovarian cancer cells
Sample name OVCAR-3
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.09-1.15 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
44
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
45
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
46
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
47
Experiment ID 63
MISEV standards
✘ Biophysical techniques
✔
AQP2
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19056867    
Organism Homo sapiens
Experiment description Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors "Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name JASN
Publication year 2009
Sample Urine
Sample name Urine - Normal
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
 Protein-protein interactions for GNB2L1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 ITGB1 3688
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
2 EIF3A 8661
Affinity Capture-MS Homo sapiens
3 RPL9 6133
Affinity Capture-MS Homo sapiens
4 ISG15 9636
Affinity Capture-MS Homo sapiens
5 TRMT1L 81627
Affinity Capture-MS Homo sapiens
6 DGCR14  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
7 UBL4A 8266
Affinity Capture-MS Homo sapiens
8 EXOSC3 51010
Affinity Capture-MS Homo sapiens
9 KRTCAP2 200185
Affinity Capture-MS Homo sapiens
10 EIF3C 8663
Affinity Capture-MS Homo sapiens
11 RIN3  
Affinity Capture-MS Homo sapiens
12 SKI 6497
Affinity Capture-MS Homo sapiens
13 TRIM26 7726
Affinity Capture-MS Homo sapiens
14 RPS14 6208
Affinity Capture-MS Homo sapiens
15 EIF2B2 8892
Affinity Capture-MS Homo sapiens
16 ACTC1 70
Affinity Capture-MS Homo sapiens
17 GAK 2580
Affinity Capture-MS Homo sapiens
18 BRCA1 672
Affinity Capture-MS Homo sapiens
19 KIF20A 10112
Affinity Capture-MS Homo sapiens
20 CSNK2A1 1457
Affinity Capture-MS Homo sapiens
21 VHL  
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
22 SLC27A6  
Two-hybrid Homo sapiens
23 MID1 4281
Affinity Capture-Western Homo sapiens
24 EIF4E2  
Affinity Capture-MS Homo sapiens
25 SOX2  
Affinity Capture-MS Homo sapiens
26 RIOK1 83732
Affinity Capture-MS Homo sapiens
27 IGF2BP3 10643
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
28 WDR76  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 DTX3  
Affinity Capture-MS Homo sapiens
30 DARS 1615
Affinity Capture-MS Homo sapiens
31 HDLBP 3069
Affinity Capture-MS Homo sapiens
32 METAP2 10988
Affinity Capture-MS Homo sapiens
33 AI837181  
Affinity Capture-MS Mus musculus
34 SRC 6714
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
35 PIK3C3 5289
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
36 RHOA 387
Two-hybrid Homo sapiens
37 GSPT1 2935
Affinity Capture-MS Homo sapiens
38 EIF3E 3646
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
39 DYNLL1 8655
Affinity Capture-Western Homo sapiens
Co-fractionation Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
40 SFN 2810
Affinity Capture-MS Homo sapiens
41 ZNF598 90850
Affinity Capture-MS Homo sapiens
42 RPS11 6205
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
43 SREK1 140890
Affinity Capture-MS Homo sapiens
44 MLEC 9761
Affinity Capture-MS Homo sapiens
45 EEF1A1 1915
Co-fractionation Homo sapiens
46 KIF14 9928
Affinity Capture-MS Homo sapiens
47 EMC9  
Affinity Capture-MS Homo sapiens
48 UNK  
Affinity Capture-RNA Homo sapiens
49 CMAS 55907
Affinity Capture-MS Homo sapiens
50 RFC5 5985
Affinity Capture-MS Homo sapiens
51 MEPCE 56257
Affinity Capture-MS Homo sapiens
52 PABPC1 26986
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
53 CDH1 999
Proximity Label-MS Homo sapiens
54 FYN 2534
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
55 YAP1 10413
Affinity Capture-MS Homo sapiens
56 TYK2 7297
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
57 TRIM21 6737
Affinity Capture-MS Homo sapiens
58 SLX4  
Affinity Capture-MS Homo sapiens
59 RPL31 6160
Affinity Capture-MS Homo sapiens
60 SYNCRIP 10492
Co-fractionation Homo sapiens
61 ASCC2 84164
Affinity Capture-MS Homo sapiens
62 NOB1  
Affinity Capture-MS Homo sapiens
63 HECTD1 25831
Affinity Capture-MS Homo sapiens
64 CUL2 8453
Affinity Capture-Western Homo sapiens
65 RRP1B 23076
Affinity Capture-MS Homo sapiens
66 ITGB2 3689
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
67 SEC61B 10952
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 SRPK1 6732
Affinity Capture-MS Homo sapiens
69 ANLN 54443
Affinity Capture-MS Homo sapiens
70 PTN  
Two-hybrid Homo sapiens
71 EIF3G 8666
Affinity Capture-MS Homo sapiens
72 RBM39 9584
Affinity Capture-MS Homo sapiens
73 DNAJC21  
Affinity Capture-MS Homo sapiens
74 SIRT7  
Affinity Capture-MS Homo sapiens
75 ZNF622 90441
Affinity Capture-MS Homo sapiens
76 ACAD11 84129
Affinity Capture-MS Homo sapiens
77 ZSCAN12  
Two-hybrid Homo sapiens
78 MTNR1A  
Two-hybrid Homo sapiens
79 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
80 LRRC47 57470
Affinity Capture-MS Homo sapiens
81 EIF4E 1977
Affinity Capture-MS Homo sapiens
82 EIF2S2 8894
Affinity Capture-MS Homo sapiens
83 TBXA2R 6915
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
84 FN1 2335
Affinity Capture-MS Homo sapiens
85 PCBP1 5093
Proximity Label-MS Homo sapiens
Co-fractionation Homo sapiens
86 STAT1 6772
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
87 RPA3 6119
Proximity Label-MS Homo sapiens
88 GRIN2B  
Affinity Capture-Western Homo sapiens
89 EIF2D 1939
Affinity Capture-MS Homo sapiens
90 RPP40 10799
Affinity Capture-MS Homo sapiens
91 DDX54 79039
Affinity Capture-MS Homo sapiens
92 Rpl35 66489
Affinity Capture-MS Mus musculus
93 PRKAB2 5565
Two-hybrid Homo sapiens
94 GNL3 26354
Affinity Capture-MS Homo sapiens
95 KCNA5  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
96 RPS16 6217
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
97 RASA1 5921
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
98 PAFAH1B1 5048
Cross-Linking-MS (XL-MS) Homo sapiens
99 EIF1AD 84285
Affinity Capture-MS Homo sapiens
100 CCDC58 131076
Co-fractionation Homo sapiens
101 IARS 3376
Affinity Capture-MS Homo sapiens
102 SLC5A5 6528
Affinity Capture-MS Homo sapiens
103 EIF3I 8668
Affinity Capture-MS Homo sapiens
104 RRP1 8568
Affinity Capture-MS Homo sapiens
105 PIK3R4 30849
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
106 RASA3 22821
Affinity Capture-Western Homo sapiens
107 DIMT1 27292
Affinity Capture-MS Homo sapiens
108 G3BP2 9908
Affinity Capture-MS Homo sapiens
109 RPS15A 6210
Affinity Capture-MS Homo sapiens
110 IL4R  
Reconstituted Complex Homo sapiens
111 WWP2 11060
Affinity Capture-MS Homo sapiens
112 IK 3550
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
113 IFNAR2 3455
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
114 NCL 4691
Affinity Capture-MS Homo sapiens
115 PRKCA 5578
Affinity Capture-Western Homo sapiens
116 PRKCE 5581
Affinity Capture-Western Homo sapiens
Far Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
117 ACO2 50
Affinity Capture-MS Homo sapiens
118 LDLR 3949
Positive Genetic Homo sapiens
119 CUL7 9820
Affinity Capture-MS Homo sapiens
120 ANXA2 302
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
121 PLD6  
Affinity Capture-MS Homo sapiens
122 HERC5 51191
Affinity Capture-MS Homo sapiens
123 DERL1 79139
Affinity Capture-MS Homo sapiens
124 CKMT2  
Affinity Capture-MS Homo sapiens
125 PRKAA1 5562
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
126 EXOSC7 23016
Affinity Capture-MS Homo sapiens
127 SPRTN  
Affinity Capture-MS Homo sapiens
128 ATG5 9474
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
129 EIF2S3 1968
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
130 EIF3K 27335
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
131 TARDBP 23435
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
132 RPA2 6118
Proximity Label-MS Homo sapiens
133 ADRB2  
Affinity Capture-MS Homo sapiens
PCA Homo sapiens
Affinity Capture-Luminescence Homo sapiens
Affinity Capture-Western Homo sapiens
134 TRIM33 51592
Affinity Capture-MS Homo sapiens
135 USP16  
Affinity Capture-MS Homo sapiens
136 RPL14 9045
Affinity Capture-MS Homo sapiens
137 RIOK3 8780
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
138 CAND1 55832
Affinity Capture-MS Homo sapiens
139 RSBN1  
Affinity Capture-MS Homo sapiens
140 GAN 8139
Affinity Capture-MS Homo sapiens
141 RPS3 6188
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
142 RPS18 6222
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
143 PPTC7 160760
Affinity Capture-MS Homo sapiens
144 B3GNT2 10678
Affinity Capture-MS Homo sapiens
145 EXOSC2 23404
Affinity Capture-MS Homo sapiens
146 HELZ 9931
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
147 H1FX 8971
Affinity Capture-MS Homo sapiens
148 WDR83  
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
149 PRC1 9055
Affinity Capture-MS Homo sapiens
150 NPM1 4869
Affinity Capture-MS Homo sapiens
151 OBSL1 23363
Affinity Capture-MS Homo sapiens
152 PLCG1 5335
Far Western Homo sapiens
153 HIST1H3A 8350
Affinity Capture-Western Homo sapiens
154 PRRC2B  
Affinity Capture-MS Homo sapiens
155 VCAM1 7412
Affinity Capture-MS Homo sapiens
156 DDX6 1656
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 TIAL1 7073
Co-fractionation Homo sapiens
158 Eif3a 13669
Affinity Capture-MS Mus musculus
159 CUL1 8454
Affinity Capture-MS Homo sapiens
160 HSD17B4 3295
Co-fractionation Homo sapiens
161 RBM42  
Affinity Capture-MS Homo sapiens
162 TP53BP1 7158
Affinity Capture-MS Homo sapiens
163 LARP4B 23185
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 ATXN2 6311
Affinity Capture-MS Homo sapiens
165 RPS9 6203
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
166 PPP5C 5536
Affinity Capture-MS Homo sapiens
167 HIST1H4A 8359
Affinity Capture-Western Homo sapiens
168 USP10 9100
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
169 CDKN1A  
Two-hybrid Homo sapiens
170 RPL4 6124
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
171 RBM28 55131
Affinity Capture-MS Homo sapiens
172 DRG1 4733
Affinity Capture-MS Homo sapiens
173 AGTRAP 57085
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
174 CSF2RB  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
175 NOL7  
Affinity Capture-MS Homo sapiens
176 C9orf72  
Affinity Capture-MS Homo sapiens
177 NKRF 55922
Affinity Capture-MS Homo sapiens
178 RPS24 6229
Affinity Capture-MS Homo sapiens
179 CTNNB1 1499
Affinity Capture-MS Homo sapiens
180 NOMO3 408050
Affinity Capture-MS Homo sapiens
181 LYAR 55646
Affinity Capture-MS Homo sapiens
182 Rrbp1  
Affinity Capture-MS Mus musculus
183 UBE2L6 9246
Affinity Capture-MS Homo sapiens
184 RPLP0 6175
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
185 TP53INP2  
Affinity Capture-MS Homo sapiens
186 Ksr1  
Affinity Capture-MS Mus musculus
187 INO80  
Affinity Capture-MS Homo sapiens
188 AIMP2 7965
Affinity Capture-MS Homo sapiens
189 HNRNPD 3184
Affinity Capture-MS Homo sapiens
190 PTOV1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
191 SYN2 6854
Affinity Capture-Western Homo sapiens
192 RPS2 6187
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
193 POP1 10940
Affinity Capture-MS Homo sapiens
194 EIF6 3692
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
195 RC3H2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
196 PRKAR2A 5576
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
197 USP54 159195
Two-hybrid Homo sapiens
198 EGFR 1956
Negative Genetic Homo sapiens
199 ADH1B 125
Two-hybrid Homo sapiens
200 ATG14  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
201 LARS 51520
Affinity Capture-MS Homo sapiens
202 RPS27 6232
Co-fractionation Homo sapiens
203 CDK2 1017
Affinity Capture-MS Homo sapiens
204 MYC  
Affinity Capture-MS Homo sapiens
205 BAG1 573
Affinity Capture-MS Homo sapiens
206 JAK1 3716
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
207 CSNK2A2 1459
Affinity Capture-MS Homo sapiens
208 FOCAD 54914
Affinity Capture-MS Homo sapiens
209 TCEB2 6923
Reconstituted Complex Homo sapiens
210 SAP25  
Affinity Capture-MS Homo sapiens
211 IL2RB  
Reconstituted Complex Homo sapiens
212 DDRGK1 65992
Affinity Capture-MS Homo sapiens
213 BMI1  
Affinity Capture-MS Homo sapiens
214 NOP16 51491
Affinity Capture-MS Homo sapiens
215 MRPL47 57129
Affinity Capture-MS Homo sapiens
216 FTSJ3 117246
Affinity Capture-MS Homo sapiens
217 LARP4 113251
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
218 HUWE1 10075
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
219 EIF3H 8667
Affinity Capture-MS Homo sapiens
220 RPL19 6143
Affinity Capture-MS Homo sapiens
Co-fractionation Homo sapiens
221 PA2G4 5036
Affinity Capture-MS Homo sapiens
222 RPL13 6137
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
223 EIF3F 8665
Affinity Capture-MS Homo sapiens
224 SPOP  
Affinity Capture-MS Homo sapiens
225 PRKCB 5579
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
226 TRAF2 7186
Affinity Capture-Western Homo sapiens
227 ILF3 3609
Affinity Capture-MS Homo sapiens
228 TP53 7157
Affinity Capture-MS Homo sapiens
229 ELAVL1 1994
Co-fractionation Homo sapiens
230 FXR1 8087
Affinity Capture-MS Homo sapiens
231 PRRC2A 7916
Affinity Capture-MS Homo sapiens
232 RPS12 6206
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
233 RPS4X 6191
Affinity Capture-MS Homo sapiens
234 SQSTM1 8878
Proximity Label-MS Homo sapiens
235 SGTB  
Affinity Capture-MS Homo sapiens
236 Htt  
Affinity Capture-MS Mus musculus
237 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
238 OTUB1 55611
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
239 GNL1 2794
Affinity Capture-MS Homo sapiens
240 RPS5 6193
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
241 MAP2K1 5604
Affinity Capture-MS Homo sapiens
242 ESR1  
Reconstituted Complex Homo sapiens
243 EIF3J 8669
Affinity Capture-MS Homo sapiens
244 EIF3M 10480
Affinity Capture-MS Homo sapiens
245 TEFM  
Affinity Capture-MS Homo sapiens
246 YBX3 8531
Affinity Capture-MS Homo sapiens
247 RPL7A 6130
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
248 SLC9A3R1 9368
Affinity Capture-Western Homo sapiens
249 CISH  
Affinity Capture-Western Homo sapiens
250 KRAS 3845
Affinity Capture-MS Homo sapiens
Negative Genetic Homo sapiens
251 GOLM1 51280
Two-hybrid Homo sapiens
252 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
253 SEC61A1 29927
Affinity Capture-MS Homo sapiens
254 TEX10 54881
Affinity Capture-MS Homo sapiens
255 RANBP2 5903
Cross-Linking-MS (XL-MS) Homo sapiens
256 RPSA 3921
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Cross-Linking-MS (XL-MS) Homo sapiens
257 RPL26L1 51121
Affinity Capture-MS Homo sapiens
258 TCEB1 6921
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
259 SDAD1  
Affinity Capture-MS Homo sapiens
260 RPS19 6223
Affinity Capture-MS Homo sapiens
261 BYSL 705
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
262 FAU 2197
Affinity Capture-MS Homo sapiens
263 ATG13 9776
Affinity Capture-MS Homo sapiens
264 CAPZB 832
Affinity Capture-MS Homo sapiens
265 RPL10A 4736
Affinity Capture-MS Homo sapiens
266 DYNC1LI2 1783
Co-fractionation Homo sapiens
267 MCM2 4171
Affinity Capture-MS Homo sapiens
268 DAZAP1 26528
Co-fractionation Homo sapiens
269 CCNA1  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
270 EIF3B 8662
Affinity Capture-MS Homo sapiens
271 RANBP1 5902
Cross-Linking-MS (XL-MS) Homo sapiens
272 MDC1  
Affinity Capture-MS Homo sapiens
273 SRP19 6728
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
274 EPOR  
Reconstituted Complex Homo sapiens
275 ATG16L1 55054
Affinity Capture-MS Homo sapiens
276 MTDH 92140
Affinity Capture-MS Homo sapiens
277 MAVS 57506
Affinity Capture-Western Homo sapiens
278 CYLD  
Affinity Capture-MS Homo sapiens
279 SMARCA2 6595
Affinity Capture-MS Homo sapiens
280 PABPC4 8761
Affinity Capture-MS Homo sapiens
281 RBM8A 9939
Affinity Capture-MS Homo sapiens
282 INSIG2  
Affinity Capture-MS Homo sapiens
283 BRIX1 55299
Affinity Capture-MS Homo sapiens
284 RPL27 6155
Affinity Capture-MS Homo sapiens
285 CNOT2  
Two-hybrid Homo sapiens
286 UBE2T  
Co-fractionation Homo sapiens
287 BCL2L11  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
288 PARK2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
289 IGF1R 3480
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
290 RPS10 6204
Affinity Capture-MS Homo sapiens
291 MARS 4141
Affinity Capture-MS Homo sapiens
292 PNO1 56902
Affinity Capture-MS Homo sapiens
293 RPL5 6125
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
294 MKRN2 23609
Two-hybrid Homo sapiens
295 ANKRD35  
Affinity Capture-MS Homo sapiens
296 BTF3 689
Affinity Capture-MS Homo sapiens
297 RAN 5901
Cross-Linking-MS (XL-MS) Homo sapiens
298 NTRK1 4914
Affinity Capture-MS Homo sapiens
299 LAS1L 81887
Affinity Capture-MS Homo sapiens
300 U2AF2 11338
Affinity Capture-MS Homo sapiens
301 RPL36 25873
Affinity Capture-MS Homo sapiens
302 RPLP1 6176
Affinity Capture-MS Homo sapiens
303 DHX9 1660
Affinity Capture-MS Homo sapiens
304 ENY2 56943
Affinity Capture-MS Homo sapiens
305 SEC61G 23480
Affinity Capture-MS Homo sapiens
306 PELP1 27043
Affinity Capture-MS Homo sapiens
307 FUBP1 8880
Co-fractionation Homo sapiens
308 SAT1  
Reconstituted Complex Homo sapiens
309 HMGB2 3148
Affinity Capture-MS Homo sapiens
310 PCBP2 5094
Co-fractionation Homo sapiens
311 LARP1 23367
Affinity Capture-MS Homo sapiens
312 VCAN 1462
Affinity Capture-MS Homo sapiens
313 HABP4  
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
314 RPL23A 6147
Affinity Capture-MS Homo sapiens
315 AK2 204
Co-fractionation Homo sapiens
316 METTL14  
Affinity Capture-MS Homo sapiens
317 CHERP 10523
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
318 ECT2 1894
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
319 ASCC1 51008
Affinity Capture-MS Homo sapiens
320 EEF2 1938
Affinity Capture-MS Homo sapiens
321 TRAF6 7189
Affinity Capture-Western Homo sapiens
322 PDE4D  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
323 RPL21 6144
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
324 ISG20L2 81875
Affinity Capture-MS Homo sapiens
325 GLI1  
Affinity Capture-MS Homo sapiens
326 FBXO6 26270
Affinity Capture-MS Homo sapiens
327 EIF4A1 1973
Affinity Capture-MS Homo sapiens
328 MAP3K7  
Affinity Capture-Western Homo sapiens
329 TP73  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
330 PDCD4 27250
Affinity Capture-MS Homo sapiens
331 NCAPH 23397
Affinity Capture-MS Homo sapiens
332 PSPC1 55269
Affinity Capture-MS Homo sapiens
333 FXR2 9513
Affinity Capture-MS Homo sapiens
334 RPS13 6207
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
335 APEH 327
Affinity Capture-MS Homo sapiens
336 HNRNPH2 3188
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
337 TP63  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
338 RPL12 6136
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
339 RPL22 6146
Affinity Capture-MS Homo sapiens
340 ACTN2 88
Two-hybrid Homo sapiens
341 RPN1 6184
Affinity Capture-MS Homo sapiens
342 RPL18 6141
Affinity Capture-MS Homo sapiens
343 RNF2  
Affinity Capture-MS Homo sapiens
344 KTN1 3895
Affinity Capture-MS Homo sapiens
345 RNF185  
Affinity Capture-MS Homo sapiens
346 HSPA9 3313
Co-fractionation Homo sapiens
347 TSR1 55720
Affinity Capture-MS Homo sapiens
348 HIF1A 3091
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Reconstituted Complex Homo sapiens
349 AHSA1 10598
Affinity Capture-Western Homo sapiens
350 EIF2S1 1965
Affinity Capture-MS Homo sapiens
351 POP7  
Affinity Capture-MS Homo sapiens
352 PLEKHA4 57664
Affinity Capture-MS Homo sapiens
353 MAP2K6 5608
Affinity Capture-Western Homo sapiens
354 RPS25 6230
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
355 RPL6 6128
Affinity Capture-MS Homo sapiens
356 RPS21 6227
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
357 RGPD2  
Cross-Linking-MS (XL-MS) Homo sapiens
358 PRRC2C 23215
Affinity Capture-MS Homo sapiens
359 G3BP1 10146
Affinity Capture-MS Homo sapiens
360 TNRC6C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
361 GNB1 2782
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
362 DDX58 23586
Affinity Capture-RNA Homo sapiens
363 MKI67  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
364 RPL34 6164
Affinity Capture-MS Homo sapiens
365 UFL1 23376
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
366 TNFRSF11A  
Affinity Capture-Western Homo sapiens
367 RPL38 6169
Affinity Capture-MS Homo sapiens
368 GTPBP4 23560
Affinity Capture-MS Homo sapiens
369 RPS7 6201
Affinity Capture-MS Homo sapiens
370 RPL8 6132
Affinity Capture-MS Homo sapiens
371 RPL28 6158
Affinity Capture-MS Homo sapiens
372 RPS27L 51065
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
373 SERBP1 26135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
374 AR 367
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
375 RC3H1 149041
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
376 ATXN3 4287
Affinity Capture-MS Homo sapiens
377 DAP  
Affinity Capture-MS Homo sapiens
378 EP300 2033
Affinity Capture-MS Homo sapiens
379 EIF5 1983
Affinity Capture-MS Homo sapiens
380 EIF3L 51386
Affinity Capture-MS Homo sapiens
381 GNL2 29889
Affinity Capture-MS Homo sapiens
382 UBE2H 7328
Affinity Capture-MS Homo sapiens
383 INSIG1  
Affinity Capture-MS Homo sapiens
384 SLFN11 91607
Proximity Label-MS Homo sapiens
385 GRAP2 9402
Reconstituted Complex Homo sapiens
386 RIT1 6016
Negative Genetic Homo sapiens
387 RSBN1L  
Affinity Capture-MS Homo sapiens
388 QARS 5859
Affinity Capture-MS Homo sapiens
389 PAXIP1  
Affinity Capture-MS Homo sapiens
390 RPS3A 6189
Co-fractionation Homo sapiens
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
391 RPL13A 23521
Affinity Capture-MS Homo sapiens
392 RPL37A 6168
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
393 RPL10 6134
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
394 RPL15 6138
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
395 PRPF3  
Affinity Capture-MS Homo sapiens
396 DHX57 90957
Affinity Capture-MS Homo sapiens
397 PIR 8544
Co-fractionation Homo sapiens
398 CCDC124 115098
Affinity Capture-MS Homo sapiens
399 CAB39 51719
Co-fractionation Homo sapiens
400 ILF2 3608
Affinity Capture-MS Homo sapiens
401 TOP2A 7153
Affinity Capture-MS Homo sapiens
402 RPS20 6224
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
403 TSC22D4 81628
Two-hybrid Homo sapiens
404 TGFB1 7040
Affinity Capture-MS Homo sapiens
405 Cep55 74107
Affinity Capture-MS Mus musculus
406 COPS5 10987
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
407 FBXW7  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-MS Homo sapiens
408 RPL24 6152
Affinity Capture-MS Homo sapiens
409 ABCE1 6059
Affinity Capture-MS Homo sapiens
410 AGTR1  
Affinity Capture-Western Homo sapiens
411 ZCCHC3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
412 STAU2 27067
Affinity Capture-MS Homo sapiens
413 ALK 238
Affinity Capture-MS Homo sapiens
414 SRP68 6730
Affinity Capture-MS Homo sapiens
415 MYCN  
Affinity Capture-MS Homo sapiens
416 SSR3 6747
Affinity Capture-MS Homo sapiens
417 ERI1  
Affinity Capture-MS Homo sapiens
418 CTCF  
Affinity Capture-MS Homo sapiens
419 RPS26 6231
Affinity Capture-MS Homo sapiens
420 LSM12 124801
Co-fractionation Homo sapiens
421 TPT1 7178
Affinity Capture-MS Homo sapiens
422 CPEB1  
Proximity Label-MS Homo sapiens
423 DDX19B 11269
Two-hybrid Homo sapiens
424 RB1 5925
Affinity Capture-Western Homo sapiens
425 E2F4  
Affinity Capture-MS Homo sapiens
426 RPS23 6228
Affinity Capture-MS Homo sapiens
427 SRP9 6726
Affinity Capture-MS Homo sapiens
428 HSP90B1 7184
Co-fractionation Homo sapiens
429 STAU1 6780
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
430 IFI16 3428
Affinity Capture-MS Homo sapiens
431 WIPI1 55062
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
432 ARRDC3 57561
Two-hybrid Homo sapiens
433 RPL27A 6157
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
434 EZH2  
Affinity Capture-MS Homo sapiens
435 ZC3H15 55854
Affinity Capture-MS Homo sapiens
436 PRPF31 26121
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
437 PPAN 56342
Affinity Capture-MS Homo sapiens
438 PTPRM 5797
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
439 ASCC3 10973
Affinity Capture-MS Homo sapiens
440 RPLP2 6181
Affinity Capture-MS Homo sapiens
441 FANCD2  
Affinity Capture-MS Homo sapiens
442 CUL3 8452
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
443 CDK9 1025
Affinity Capture-MS Homo sapiens
444 OTUD1 220213
Affinity Capture-MS Homo sapiens
445 NR3C1 2908
Two-hybrid Homo sapiens
446 DNAJC2 27000
Affinity Capture-MS Homo sapiens
447 RPL35 11224
Affinity Capture-MS Homo sapiens
448 RLIM 51132
Affinity Capture-MS Homo sapiens
449 RPS6 6194
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
450 RPL3 6122
Affinity Capture-MS Homo sapiens
451 RPL7 6129
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
452 SUZ12  
Affinity Capture-MS Homo sapiens
453 AURKB 9212
Two-hybrid Homo sapiens
454 JUN 3725
Affinity Capture-Western Homo sapiens
455 MAP7D1 55700
Affinity Capture-MS Homo sapiens
456 MAPK6  
Two-hybrid Homo sapiens
457 IL7R  
Protein-RNA Homo sapiens
458 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
459 DHX30 22907
Affinity Capture-MS Homo sapiens
460 RPL11 6135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
461 NANOG  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
462 NSMAF  
Two-hybrid Homo sapiens
Affinity Capture-Western Homo sapiens
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
463 EXOSC10 5394
Affinity Capture-MS Homo sapiens
464 GNG2 54331
Affinity Capture-Western Homo sapiens
465 RRBP1 6238
Affinity Capture-MS Homo sapiens
466 GGN  
Two-hybrid Homo sapiens
467 VPS37C 55048
Affinity Capture-MS Homo sapiens
468 TRIM45  
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
469 MNDA 4332
Affinity Capture-MS Homo sapiens
470 ZNF746  
Affinity Capture-MS Homo sapiens
471 NUFIP2 57532
Affinity Capture-MS Homo sapiens
472 SMURF1 57154
Affinity Capture-MS Homo sapiens
473 RPS15 6209
Affinity Capture-MS Homo sapiens
474 SRP72 6731
Affinity Capture-MS Homo sapiens
475 FEM1B 10116
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
476 ARF4 378
Co-fractionation Homo sapiens
477 RPS28 6234
Affinity Capture-MS Homo sapiens
478 BECN1 8678
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
479 TRIP4 9325
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
480 TRIM31  
Affinity Capture-MS Homo sapiens
481 PINK1  
Affinity Capture-MS Homo sapiens
482 KCNAB1  
Affinity Capture-Western Homo sapiens
483 RPS8 6202
Co-fractionation Homo sapiens
Affinity Capture-MS Homo sapiens
484 GNB2L1 10399
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
485 WDR60 55112
Affinity Capture-MS Homo sapiens
486 LTV1  
Affinity Capture-MS Homo sapiens
487 RPL17 6139
Affinity Capture-MS Homo sapiens
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here