Gene description for EIF2D
Gene name eukaryotic translation initiation factor 2D
Gene symbol EIF2D
Other names/aliases HCA56
Species Homo sapiens
 Database cross references - EIF2D
ExoCarta ExoCarta_1939
Entrez Gene 1939
HGNC 6583
MIM 613709
UniProt P41214  
 EIF2D identified in exosomes derived from the following tissue/cell type
Thymus 23844026    
 Gene ontology annotations for EIF2D
Molecular Function
    receptor activity GO:0004872 TAS
    translation initiation factor activity GO:0003743 IDA
Biological Process
    ribosome disassembly GO:0032790 IDA
    IRES-dependent translational initiation GO:0002192 IDA
    intracellular protein transport GO:0006886 TAS
    formation of translation preinitiation complex GO:0001731 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
    cytoplasm GO:0005737 IDA
    nucleoplasm GO:0005654 IDA
    cytosolic small ribosomal subunit GO:0022627 IDA
 Experiment description of studies that identified EIF2D in exosomes
Experiment ID 217
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O.
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for EIF2D
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HEXB 3074
Invitro Homo sapiens
2 ACHE  
Invivo Homo sapiens
3 RAD51  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which EIF2D is involved
No pathways found

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