Gene description for RRP1
Gene name ribosomal RNA processing 1
Gene symbol RRP1
Other names/aliases D21S2056E
NNP-1
NOP52
RRP1A
Species Homo sapiens
 Database cross references - RRP1
ExoCarta ExoCarta_8568
Entrez Gene 8568
HGNC 18785
MIM 610653
UniProt P56182  
 RRP1 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for RRP1
Molecular Function
    poly(A) RNA binding GO:0044822 IDA
Biological Process
    rRNA processing GO:0006364 IEA
Subcellular Localization
    nucleus GO:0005634 TAS
    preribosome, small subunit precursor GO:0030688 IEA
    nucleolus GO:0005730 IDA
 Experiment description of studies that identified RRP1 in exosomes
1
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for RRP1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which RRP1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here