Gene description for IFI16
Gene name interferon, gamma-inducible protein 16
Gene symbol IFI16
Other names/aliases IFNGIP1
PYHIN2
Species Homo sapiens
 Database cross references - IFI16
ExoCarta ExoCarta_3428
Vesiclepedia VP_3428
Entrez Gene 3428
HGNC 5395
MIM 147586
UniProt Q16666  
 IFI16 identified in sEVs derived from the following tissue/cell type
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Breast cancer cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Embryonic kidney cells 34108659    
Foreskin fibroblasts 34108659    
Lymphoma cells 34108659    
Mammary cancer-associated fibroblasts 34108659    
Mesenchymal stem cells 36408942    
Monocytic leukemia cells 34108659    
Normal mammary epithelial cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic cancer cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pancreatic duct epithalial cells 34108659    
Pluripotent stem cells 34108659    
Squamous carcinoma cells 20124223    
T lymphocytes 34108659    
Thymus 23844026    
 Gene ontology annotations for IFI16
Molecular Function
    double-stranded DNA binding GO:0003690 IBA
    double-stranded DNA binding GO:0003690 IDA
    RNA binding GO:0003723 HDA
    protein binding GO:0005515 IPI
    transcription factor binding GO:0008134 IDA
    identical protein binding GO:0042802 IPI
Biological Process
    negative regulation of transcription by RNA polymerase II GO:0000122 IDA
    negative regulation of transcription by RNA polymerase II GO:0000122 IMP
    positive regulation of cytokine production GO:0001819 TAS
    activation of innate immune response GO:0002218 IBA
    activation of innate immune response GO:0002218 IDA
    autophagy GO:0006914 IEA
    inflammatory response GO:0006954 IEA
    regulation of autophagy GO:0010506 IEP
    myeloid cell differentiation GO:0030099 NAS
    monocyte differentiation GO:0030224 IDA
    positive regulation of interleukin-1 beta production GO:0032731 IDA
    cellular response to interferon-beta GO:0035458 IBA
    cellular response to glucose starvation GO:0042149 IDA
    intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator GO:0042771 IDA
    negative regulation of DNA binding GO:0043392 IDA
    negative regulation of viral genome replication GO:0045071 IDA
    innate immune response GO:0045087 IEA
    negative regulation of gene expression, epigenetic GO:0045814 IMP
    negative regulation of innate immune response GO:0045824 IDA
    negative regulation of DNA-templated transcription GO:0045892 IDA
    positive regulation of transcription by RNA polymerase II GO:0045944 IDA
    positive regulation of transcription by RNA polymerase II GO:0045944 IMP
    defense response to virus GO:0051607 IDA
    defense response to virus GO:0051607 IMP
    cellular response to ionizing radiation GO:0071479 IDA
    intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 IMP
    activation of cysteine-type endopeptidase activity GO:0097202 IMP
    negative regulation of AIM2 inflammasome complex assembly GO:0140972 IDA
    negative regulation of cysteine-type endopeptidase activity GO:2000117 IDA
Subcellular Localization
    nucleus GO:0005634 IDA
    nucleoplasm GO:0005654 IBA
    nucleoplasm GO:0005654 IDA
    nucleolus GO:0005730 IBA
    nucleolus GO:0005730 IDA
    cytoplasm GO:0005737 IDA
    cytosol GO:0005829 IDA
    cytosol GO:0005829 IPI
    cytosol GO:0005829 TAS
    membrane GO:0016020 HDA
    nuclear speck GO:0016607 IDA
 Experiment description of studies that identified IFI16 in sEVs
1
Experiment ID 412
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MCF7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
2
Experiment ID 414
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
3
Experiment ID 426
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
4
Experiment ID 427
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Breast cancer cells
Sample name MDA-MB-231 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
5
Experiment ID 407
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|TSG101|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
6
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
7
Experiment ID 419
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
8
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
9
Experiment ID 420
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Embryonic kidney cells
Sample name HEK293T - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
10
Experiment ID 405
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Foreskin fibroblasts
Sample name BJ
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
11
Experiment ID 417
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Lymphoma cells
Sample name Raji
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
12
Experiment ID 411
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Mammary cancer-associated fibroblasts
Sample name mCAF
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
13
Experiment ID 488
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD81|CD63|GAPDH|SDCBP|LAMP1|TFRC|UCHL1|FLOT2|LAMP2|FLOT1|ICAM1|RAB5B|CD151|RAB35|TSG101|RAB5A|CD82
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
14
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
15
Experiment ID 418
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Monocytic leukemia cells
Sample name THP-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
16
Experiment ID 413
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Normal mammary epithelial cells
Sample name MCF10A
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
17
Experiment ID 406
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35|CD81
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name BxPC3
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
18
Experiment ID 415
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
19
Experiment ID 434
MISEV standards
✘ Biophysical techniques
✔
SDCBP|FLOT1|CD81|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 7-10 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Size exclusion chromatography
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
20
Experiment ID 435
MISEV standards
✘ Biophysical techniques
✔
CD81|SDCBP|FLOT1|CD9|CD151|FLOT2|TSG101|LAMP1|TFRC|RAB5A|RAB35|GAPDH|UCHL1|ICAM1
Enriched markers
✔
CANX
Negative markers
✘ Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic cancer cells
Sample name PANC-1 - Exo-rich fractions 1-6 pooled
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
OptiPrep density gradient centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
21
Experiment ID 408
MISEV standards
✔
EM
Biophysical techniques
✔
CD9|CD63|CD81|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX|ACTB
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPDE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
22
Experiment ID 409
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pancreatic duct epithalial cells
Sample name HPNE
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
23
Experiment ID 416
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD9|CD63|SDCBP|LAMP1|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample Pluripotent stem cells
Sample name PSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
24
Experiment ID 191
MISEV standards
✘ Biophysical techniques
✔
Alix|CD81|CD9
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 20124223    
Organism Homo sapiens
Experiment description Hypoxic tumor cell modulates its microenvironment to enhance angiogenic and metastatic potential by secretion of proteins and exosomes.
Authors "Park JE, Tan HS, Datta A, Lai RC, Zhang H, Meng W, Lim SK, Sze SK."
Journal name Mol Cell Proteomics
Publication year 2010
Sample Squamous carcinoma cells
Sample name Squamous carcinoma cell (A431)
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
25
Experiment ID 410
MISEV standards
✔
EM
Biophysical techniques
✔
CD81|CD63|SDCBP|LAMP1|CD9|GAPDH|FLOT1|TFRC|FLOT2|TSG101|RAB35
Enriched markers
✔
CANX
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 34108659    
Organism Homo sapiens
Experiment description Quantitative Proteomics Identifies the Core Proteome of Exosomes with Syntenin-1 as the highest abundant protein and a Putative Universal Biomarker
Authors "Kugeratski FG, Hodge K, Lilla S, McAndrews KM, Zhou X, Hwang RF, Zanivan S, Kalluri R."
Journal name Nat Cell Biol
Publication year 2021
Sample T lymphocytes
Sample name Jurkat
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
mRNA
Methods used in the study RT-qPCR
Western blotting
Mass spectrometry
Flow cytometry
26
Experiment ID 217
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|CD81|CD9|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23844026    
Organism Homo sapiens
Experiment description Characterization of human thymic exosomes.
Authors "Skogberg G, Gudmundsdottir J, van der Post S, Sandstrom K, Bruhn S, Benson M, Mincheva-Nilsson L, Baranov V, Telemo E, Ekwall O."
Journal name PLoS One
Publication year 2013
Sample Thymus
Sample name Normal-Thymus
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IFI16
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 EIF3A 8661
Affinity Capture-MS Homo sapiens
2 SPATS2  
Affinity Capture-MS Homo sapiens
3 SLC25A13 10165
Affinity Capture-MS Homo sapiens
4 TRMT1L 81627
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
5 EIF3C 8663
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
6 PKM 5315
Affinity Capture-MS Homo sapiens
7 PSMA4 5685
Affinity Capture-MS Homo sapiens
8 DDX21 9188
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
9 NFATC1 4772
Affinity Capture-MS Homo sapiens
10 UBA1 7317
Affinity Capture-MS Homo sapiens
11 BRCA1 672
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
12 KIF20A 10112
Affinity Capture-MS Homo sapiens
13 CSTA 1475
Affinity Capture-MS Homo sapiens
14 KPNA2 3838
Affinity Capture-MS Homo sapiens
15 TCEB3 6924
Affinity Capture-MS Homo sapiens
16 DDX23 9416
Affinity Capture-MS Homo sapiens
17 GPATCH4 54865
Affinity Capture-MS Homo sapiens
18 SNRNP70 6625
Affinity Capture-MS Homo sapiens
19 ACAP2 23527
Affinity Capture-MS Homo sapiens
20 ACTR3 10096
Affinity Capture-MS Homo sapiens
21 USP39 10713
Affinity Capture-MS Homo sapiens
22 PEG10 23089
Affinity Capture-MS Homo sapiens
23 PSMD12 5718
Affinity Capture-MS Homo sapiens
24 HSPH1 10808
Affinity Capture-MS Homo sapiens
25 MAGED2 10916
Affinity Capture-MS Homo sapiens
26 RPF2 84154
Affinity Capture-MS Homo sapiens
27 EXOSC4 54512
Affinity Capture-MS Homo sapiens
28 RBM14 10432
Affinity Capture-MS Homo sapiens
29 KIF14 9928
Affinity Capture-MS Homo sapiens
30 CHMP4C 92421
Affinity Capture-MS Homo sapiens
31 AURKA 6790
Reconstituted Complex Homo sapiens
32 TCP1 6950
Affinity Capture-MS Homo sapiens
33 UTP14A 10813
Affinity Capture-MS Homo sapiens
34 PELO 53918
Affinity Capture-MS Homo sapiens
35 MAP1B 4131
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 RBM4B  
Affinity Capture-MS Homo sapiens
37 RCL1 10171
Affinity Capture-MS Homo sapiens
38 TRMT61A 115708
Affinity Capture-MS Homo sapiens
39 PABPC1 26986
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
40 PSMD2 5708
Affinity Capture-MS Homo sapiens
41 SRBD1  
Affinity Capture-MS Homo sapiens
42 TRIM21 6737
Affinity Capture-Western Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
43 GTF3C2  
Affinity Capture-MS Homo sapiens
44 HIST1H1C 3006
Affinity Capture-MS Homo sapiens
45 ENO1 2023
Affinity Capture-MS Homo sapiens
46 SDAD1  
Affinity Capture-MS Homo sapiens
47 RRP1B 23076
Affinity Capture-MS Homo sapiens
48 SND1 27044
Affinity Capture-MS Homo sapiens
49 GTPBP4 23560
Affinity Capture-MS Homo sapiens
50 CACYBP 27101
Affinity Capture-MS Homo sapiens
51 SCARNA22  
Affinity Capture-RNA Homo sapiens
52 HIST1H2BL 8340
Cross-Linking-MS (XL-MS) Homo sapiens
53 RNF40 9810
Affinity Capture-MS Homo sapiens
54 GTF3C3 9330
Affinity Capture-MS Homo sapiens
55 RBM39 9584
Affinity Capture-MS Homo sapiens
56 RNF219  
Affinity Capture-MS Homo sapiens
57 NOC3L 64318
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 MRTO4 51154
Affinity Capture-MS Homo sapiens
59 SRSF4 6429
Affinity Capture-MS Homo sapiens
60 MYH14 79784
Affinity Capture-MS Homo sapiens
61 YWHAZ 7534
Affinity Capture-MS Homo sapiens
62 EBNA1BP2 10969
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 TRMT6 51605
Affinity Capture-MS Homo sapiens
64 PRPSAP1 5635
Affinity Capture-MS Homo sapiens
65 DHX37  
Affinity Capture-MS Homo sapiens
66 SLTM 79811
Affinity Capture-MS Homo sapiens
67 RRP15  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
68 ZNF512  
Affinity Capture-MS Homo sapiens
69 TMEM173  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
Co-localization Homo sapiens
70 PRMT5 10419
Affinity Capture-MS Homo sapiens
71 SSUH2  
Affinity Capture-MS Homo sapiens
72 RPP40 10799
Affinity Capture-MS Homo sapiens
73 AP2A2 161
Affinity Capture-MS Homo sapiens
74 OBSCN 84033
Affinity Capture-MS Homo sapiens
75 HSPA4 3308
Affinity Capture-MS Homo sapiens
76 SPATA5 166378
Affinity Capture-MS Homo sapiens
77 EIF2B1 1967
Affinity Capture-MS Homo sapiens
78 HAT1 8520
Affinity Capture-MS Homo sapiens
79 DLAT 1737
Affinity Capture-MS Homo sapiens
80 BCAS2 10286
Affinity Capture-MS Homo sapiens
81 NFATC2  
Affinity Capture-MS Homo sapiens
82 GNL3 26354
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 DDX55  
Affinity Capture-MS Homo sapiens
84 CXorf57  
Affinity Capture-MS Homo sapiens
85 NGDN  
Affinity Capture-MS Homo sapiens
86 U2SURP 23350
Affinity Capture-MS Homo sapiens
87 YBX1 4904
Affinity Capture-MS Homo sapiens
88 C8orf33 65265
Affinity Capture-MS Homo sapiens
89 SF3B1 23451
Affinity Capture-MS Homo sapiens
90 WDR77 79084
Affinity Capture-MS Homo sapiens
91 RPL6 6128
Affinity Capture-MS Homo sapiens
92 RRS1 23212
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 RBM25 58517
Affinity Capture-MS Homo sapiens
94 RUVBL2 10856
Affinity Capture-MS Homo sapiens
95 RRP1 8568
Affinity Capture-MS Homo sapiens
96 MORF4L2  
Affinity Capture-MS Homo sapiens
97 DCTN2 10540
Affinity Capture-MS Homo sapiens
98 TBL3 10607
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 G3BP2 9908
Affinity Capture-MS Homo sapiens
100 PUF60 22827
Affinity Capture-MS Homo sapiens
101 DTHD1  
Affinity Capture-MS Homo sapiens
102 DDX27 55661
Affinity Capture-MS Homo sapiens
103 PWP1 11137
Affinity Capture-MS Homo sapiens
104 KRR1 11103
Affinity Capture-MS Homo sapiens
105 NCL 4691
Affinity Capture-MS Homo sapiens
106 HNRNPL 3191
Affinity Capture-MS Homo sapiens
107 EIF4B 1975
Affinity Capture-MS Homo sapiens
108 PSMA7 5688
Affinity Capture-Western Homo sapiens
109 PCGF6  
Affinity Capture-MS Homo sapiens
110 DNAJB11 51726
Affinity Capture-MS Homo sapiens
111 HNRNPA1L2 144983
Affinity Capture-MS Homo sapiens
112 PPAN 56342
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
113 CAMK2D 817
Affinity Capture-MS Homo sapiens
114 IGKV2-40  
Affinity Capture-MS Homo sapiens
115 UTP6  
Affinity Capture-MS Homo sapiens
116 PSMC4 5704
Affinity Capture-MS Homo sapiens
117 DNMT1 1786
Affinity Capture-MS Homo sapiens
118 LUC7L 55692
Affinity Capture-MS Homo sapiens
119 NVL  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
120 HSPA1B 3304
Affinity Capture-MS Homo sapiens
121 HERC5 51191
Affinity Capture-MS Homo sapiens
122 PSMD3 5709
Affinity Capture-MS Homo sapiens
123 HNRNPH1 3187
Affinity Capture-MS Homo sapiens
124 VARS 7407
Affinity Capture-MS Homo sapiens
125 GTF3C5 9328
Affinity Capture-MS Homo sapiens
126 GART 2618
Affinity Capture-MS Homo sapiens
127 EIF2S3 1968
Affinity Capture-MS Homo sapiens
128 KIAA0020 9933
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
129 GTPBP10  
Affinity Capture-MS Homo sapiens
130 BTF3 689
Affinity Capture-MS Homo sapiens
131 UCHL1 7345
Affinity Capture-MS Homo sapiens
132 NOP56 10528
Affinity Capture-MS Homo sapiens
133 COPA 1314
Affinity Capture-MS Homo sapiens
134 PWP2 5822
Affinity Capture-MS Homo sapiens
135 RPS3 6188
Affinity Capture-MS Homo sapiens
136 Tmem173  
Reconstituted Complex Mus musculus
137 SAFB 6294
Affinity Capture-MS Homo sapiens
138 B3GNT2 10678
Affinity Capture-MS Homo sapiens
139 IGHMBP2 3508
Affinity Capture-MS Homo sapiens
140 HSP90AA1 3320
Affinity Capture-MS Homo sapiens
141 DDX24 57062
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
142 HELZ 9931
Affinity Capture-MS Homo sapiens
143 H1FX 8971
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
144 RRP12 23223
Affinity Capture-MS Homo sapiens
145 SRRM2 23524
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
146 KRI1  
Affinity Capture-MS Homo sapiens
147 GRWD1 83743
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
148 PHB 5245
Affinity Capture-MS Homo sapiens
149 E4F1  
Affinity Capture-MS Homo sapiens
150 SPIN3  
Affinity Capture-MS Homo sapiens
151 USP7 7874
Affinity Capture-MS Homo sapiens
152 PLS3 5358
Affinity Capture-MS Homo sapiens
153 LARP4B 23185
Affinity Capture-MS Homo sapiens
154 PES1 23481
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
155 HIST1H4A 8359
Affinity Capture-MS Homo sapiens
156 USP10 9100
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
157 RPL4 6124
Affinity Capture-MS Homo sapiens
158 RBM28 55131
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
159 TAB3 257397
Affinity Capture-MS Homo sapiens
160 NOL11  
Affinity Capture-MS Homo sapiens
161 RCC2 55920
Affinity Capture-MS Homo sapiens
162 DDX10  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
163 NKRF 55922
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
164 S100A8 6279
Affinity Capture-MS Homo sapiens
165 LYAR 55646
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
166 RPLP0 6175
Affinity Capture-MS Homo sapiens
167 PPM1G 5496
Affinity Capture-MS Homo sapiens
168 C7orf50 84310
Affinity Capture-MS Homo sapiens
169 RSL1D1 26156
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
170 HNRNPD 3184
Affinity Capture-MS Homo sapiens
171 TUBB 203068
Affinity Capture-MS Homo sapiens
172 ACLY 47
Affinity Capture-MS Homo sapiens
173 RPS2 6187
Affinity Capture-MS Homo sapiens
174 POP1 10940
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
175 USP15 9958
Affinity Capture-MS Homo sapiens
176 PNP 4860
Affinity Capture-MS Homo sapiens
177 PHIP 55023
Affinity Capture-MS Homo sapiens
178 SRSF5 6430
Affinity Capture-MS Homo sapiens
179 SMARCA5 8467
Affinity Capture-MS Homo sapiens
180 CIITA  
Affinity Capture-MS Homo sapiens
181 RP9  
Affinity Capture-MS Homo sapiens
182 YWHAQ 10971
Affinity Capture-MS Homo sapiens
183 EFTUD2 9343
Affinity Capture-MS Homo sapiens
184 MYC  
Affinity Capture-MS Homo sapiens
185 JAK1 3716
Affinity Capture-MS Homo sapiens
186 CEBPZ  
Affinity Capture-MS Homo sapiens
187 TMOD3 29766
Affinity Capture-MS Homo sapiens
188 HNRNPAB 3182
Affinity Capture-MS Homo sapiens
189 RCN2 5955
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
190 PGAM1 5223
Affinity Capture-MS Homo sapiens
191 NOP16 51491
Affinity Capture-MS Homo sapiens
192 MPRIP 23164
Affinity Capture-MS Homo sapiens
193 ADAR 103
Affinity Capture-MS Homo sapiens
194 FTSJ3 117246
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
195 LARP4 113251
Affinity Capture-MS Homo sapiens
196 TAF4 6874
Affinity Capture-MS Homo sapiens
197 RAE1 8480
Affinity Capture-MS Homo sapiens
198 RPL13 6137
Affinity Capture-MS Homo sapiens
199 SURF6  
Affinity Capture-MS Homo sapiens
200 EIF3F 8665
Affinity Capture-MS Homo sapiens
201 HEATR5B 54497
Affinity Capture-MS Homo sapiens
202 PARP1 142
Affinity Capture-MS Homo sapiens
203 ILF3 3609
Affinity Capture-MS Homo sapiens
204 TP53 7157
Affinity Capture-Western Homo sapiens
205 HSPA8 3312
Affinity Capture-MS Homo sapiens
206 SNRPA1 6627
Affinity Capture-MS Homo sapiens
207 FXR1 8087
Affinity Capture-MS Homo sapiens
208 PURA 5813
Affinity Capture-MS Homo sapiens
209 SIPA1L3  
Affinity Capture-MS Homo sapiens
210 KNOP1 400506
Affinity Capture-MS Homo sapiens
211 RPS4X 6191
Affinity Capture-MS Homo sapiens
212 FKBP4 2288
Affinity Capture-MS Homo sapiens
213 CAPRIN1 4076
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
214 PRKACA 5566
Affinity Capture-MS Homo sapiens
215 NIFK 84365
Affinity Capture-MS Homo sapiens
216 HNRNPK 3190
Affinity Capture-MS Homo sapiens
217 TRIP12 9320
Affinity Capture-MS Homo sapiens
218 DDX39A 10212
Affinity Capture-MS Homo sapiens
219 NOTCH1 4851
Affinity Capture-MS Homo sapiens
220 PPM1B 5495
Affinity Capture-MS Homo sapiens
221 EEF1A1P5 158078
Affinity Capture-MS Homo sapiens
222 DHX38 9785
Affinity Capture-MS Homo sapiens
223 YBX3 8531
Affinity Capture-MS Homo sapiens
224 RPL7A 6130
Affinity Capture-MS Homo sapiens
225 C1QBP 708
Affinity Capture-MS Homo sapiens
226 HSPA4L 22824
Affinity Capture-MS Homo sapiens
227 PPP2R1A 5518
Affinity Capture-MS Homo sapiens
228 TEX10 54881
Affinity Capture-MS Homo sapiens
229 PRMT1 3276
Affinity Capture-MS Homo sapiens
230 NUDT5 11164
Affinity Capture-MS Homo sapiens
231 NOP14 8602
Affinity Capture-MS Homo sapiens
232 MCM7 4176
Affinity Capture-MS Homo sapiens
233 SENP3 26168
Affinity Capture-MS Homo sapiens
234 RIOK1 83732
Affinity Capture-MS Homo sapiens
235 NOP58 51602
Affinity Capture-MS Homo sapiens
236 SP1  
Affinity Capture-Western Homo sapiens
237 ABCF1 23
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
238 SSB 6741
Affinity Capture-MS Homo sapiens
239 XRN2 22803
Affinity Capture-MS Homo sapiens
240 Ktn1  
Affinity Capture-MS Mus musculus
241 RPL10A 4736
Affinity Capture-MS Homo sapiens
242 TRIM28 10155
Affinity Capture-MS Homo sapiens
243 LLPH  
Affinity Capture-MS Homo sapiens
244 SARS2 54938
Affinity Capture-MS Homo sapiens
245 MPHOSPH10 10199
Affinity Capture-MS Homo sapiens
246 ZNF148  
Affinity Capture-MS Homo sapiens
247 MDC1  
Affinity Capture-MS Homo sapiens
248 POLR1E  
Affinity Capture-MS Homo sapiens
249 MCM6 4175
Affinity Capture-MS Homo sapiens
250 PDIA6 10130
Affinity Capture-MS Homo sapiens
251 DDX18 8886
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
252 UTP20 27340
Affinity Capture-MS Homo sapiens
253 PRDX4 10549
Affinity Capture-MS Homo sapiens
254 MTDH 92140
Affinity Capture-MS Homo sapiens
255 PABPC4 8761
Affinity Capture-MS Homo sapiens
256 FEN1 2237
Affinity Capture-MS Homo sapiens
257 BRIX1 55299
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
258 RAI14 26064
Affinity Capture-MS Homo sapiens
259 EIF2AK2 5610
Affinity Capture-MS Homo sapiens
260 NSUN2 54888
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
261 ATP5A1 498
Affinity Capture-MS Homo sapiens
262 NOP2 4839
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
263 PINX1  
Affinity Capture-MS Homo sapiens
264 CENPV 201161
Affinity Capture-MS Homo sapiens
265 MARS 4141
Affinity Capture-MS Homo sapiens
266 PNO1 56902
Affinity Capture-MS Homo sapiens
267 TUBA1B 10376
Affinity Capture-MS Homo sapiens
268 SAFB2 9667
Affinity Capture-MS Homo sapiens
269 DRG1 4733
Affinity Capture-MS Homo sapiens
270 LAS1L 81887
Affinity Capture-MS Homo sapiens
271 CIRH1A 84916
Affinity Capture-MS Homo sapiens
272 U2AF2 11338
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
273 KIF11 3832
Affinity Capture-MS Homo sapiens
274 ACTB 60
Affinity Capture-MS Homo sapiens
275 DHX9 1660
Affinity Capture-MS Homo sapiens
276 PELP1 27043
Affinity Capture-MS Homo sapiens
277 MYBBP1A 10514
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
278 DNTTIP2  
Affinity Capture-MS Homo sapiens
279 SF3A3 10946
Affinity Capture-MS Homo sapiens
280 RBM10  
Affinity Capture-MS Homo sapiens
281 PCBP2 5094
Affinity Capture-MS Homo sapiens
282 LARP1 23367
Affinity Capture-MS Homo sapiens
283 WDR46  
Affinity Capture-MS Homo sapiens
284 HNRNPCL3 649330
Affinity Capture-MS Homo sapiens
285 SPATS2L 26010
Affinity Capture-MS Homo sapiens
286 AGPAT1 10554
Affinity Capture-MS Homo sapiens
287 EXOSC10 5394
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
288 EEF2 1938
Affinity Capture-MS Homo sapiens
289 ASPM 259266
Affinity Capture-MS Homo sapiens
290 DCAF13 25879
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
291 ISG20L2 81875
Affinity Capture-MS Homo sapiens
292 E2F7  
Affinity Capture-MS Homo sapiens
293 SYNCRIP 10492
Affinity Capture-MS Homo sapiens
294 ATXN10 25814
Affinity Capture-MS Homo sapiens
295 HNRNPA1 3178
Affinity Capture-MS Homo sapiens
296 DHX30 22907
Affinity Capture-MS Homo sapiens
297 HNRNPUL1 11100
Affinity Capture-MS Homo sapiens
298 PDCD11 22984
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
299 RFC1 5981
Affinity Capture-MS Homo sapiens
300 ANKFY1 51479
Affinity Capture-MS Homo sapiens
301 PRPF19 27339
Affinity Capture-MS Homo sapiens
302 PSPC1 55269
Affinity Capture-MS Homo sapiens
303 FXR2 9513
Affinity Capture-MS Homo sapiens
304 WDR43 23160
Affinity Capture-MS Homo sapiens
305 TOP1 7150
Affinity Capture-MS Homo sapiens
306 HP1BP3 50809
Affinity Capture-MS Homo sapiens
307 SKIV2L2 23517
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
308 MATR3 9782
Affinity Capture-MS Homo sapiens
309 RANBP1 5902
Affinity Capture-MS Homo sapiens
310 KTN1 3895
Affinity Capture-MS Homo sapiens
311 ZC3HAV1 56829
Affinity Capture-MS Homo sapiens
312 HSPD1 3329
Affinity Capture-MS Homo sapiens
313 HSPA9 3313
Affinity Capture-MS Homo sapiens
314 TSR1 55720
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
315 XRCC5 7520
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
316 ATIC 471
Affinity Capture-MS Homo sapiens
317 DDX50 79009
Affinity Capture-MS Homo sapiens
318 CCT8 10694
Affinity Capture-MS Homo sapiens
319 LIG3 3980
Affinity Capture-MS Homo sapiens
320 POLR1B 84172
Affinity Capture-MS Homo sapiens
321 CDC40  
Affinity Capture-MS Homo sapiens
322 PYCARD 29108
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
323 STK38 11329
Affinity Capture-MS Homo sapiens
324 DDX3X 1654
Affinity Capture-MS Homo sapiens
325 RPA1 6117
Affinity Capture-MS Homo sapiens
326 PDHA1 5160
Affinity Capture-MS Homo sapiens
327 HNRNPM 4670
Affinity Capture-MS Homo sapiens
328 G3BP1 10146
Affinity Capture-MS Homo sapiens
329 PDIA4 9601
Affinity Capture-MS Homo sapiens
330 S100A9 6280
Affinity Capture-MS Homo sapiens
331 MKI67  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
332 TLR9  
Affinity Capture-MS Homo sapiens
333 PPP1R9A  
Affinity Capture-MS Homo sapiens
334 MBNL1 4154
Affinity Capture-MS Homo sapiens
335 RNMTL1  
Affinity Capture-MS Homo sapiens
336 MARK2 2011
Affinity Capture-MS Homo sapiens
337 FLNA 2316
Affinity Capture-MS Homo sapiens
338 MYO1E 4643
Affinity Capture-MS Homo sapiens
339 RPL8 6132
Affinity Capture-MS Homo sapiens
340 HNRNPF 3185
Affinity Capture-MS Homo sapiens
341 SERBP1 26135
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
342 AR 367
Affinity Capture-Western Homo sapiens
Reconstituted Complex Homo sapiens
343 RBM34  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
344 SLC25A5 292
Affinity Capture-MS Homo sapiens
345 DDX56  
Affinity Capture-MS Homo sapiens
346 IGF2BP2 10644
Affinity Capture-MS Homo sapiens
347 UBA52 7311
Affinity Capture-MS Homo sapiens
348 EIF3L 51386
Affinity Capture-MS Homo sapiens
349 GNL2 29889
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
350 RPSA 3921
Affinity Capture-MS Homo sapiens
351 UTP18  
Affinity Capture-MS Homo sapiens
352 IGF2BP1 10642
Affinity Capture-MS Homo sapiens
353 RSBN1L  
Affinity Capture-MS Homo sapiens
354 CDK11B 984
Affinity Capture-MS Homo sapiens
355 QARS 5859
Affinity Capture-MS Homo sapiens
356 RPS3A 6189
Affinity Capture-MS Homo sapiens
357 MSH6 2956
Affinity Capture-MS Homo sapiens
358 HIST1H1D 3007
Affinity Capture-MS Homo sapiens
359 RPL10 6134
Affinity Capture-MS Homo sapiens
360 RPL15 6138
Affinity Capture-MS Homo sapiens
361 TAB1 10454
Affinity Capture-MS Homo sapiens
362 KARS 3735
Affinity Capture-MS Homo sapiens
363 PRPF3  
Affinity Capture-MS Homo sapiens
364 BUD13  
Affinity Capture-MS Homo sapiens
365 APP 351
Reconstituted Complex Homo sapiens
366 WDR36 134430
Affinity Capture-MS Homo sapiens
367 HSPA5 3309
Affinity Capture-MS Homo sapiens
368 ILF2 3608
Affinity Capture-MS Homo sapiens
369 CTSD 1509
Affinity Capture-MS Homo sapiens
370 RNH1 6050
Affinity Capture-MS Homo sapiens
371 CHD4 1108
Affinity Capture-MS Homo sapiens
372 CASP1  
Affinity Capture-Western Homo sapiens
Affinity Capture-Western Homo sapiens
Co-localization Homo sapiens
373 TBCB 1155
Affinity Capture-MS Homo sapiens
374 KIF5B 3799
Affinity Capture-MS Homo sapiens
375 FBXW7  
Affinity Capture-MS Homo sapiens
376 WDR12 55759
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
377 YWHAG 7532
Affinity Capture-MS Homo sapiens
378 ZCCHC3  
Affinity Capture-MS Homo sapiens
379 IPO8 10526
Affinity Capture-MS Homo sapiens
380 DDX51  
Affinity Capture-MS Homo sapiens
381 SRP68 6730
Affinity Capture-MS Homo sapiens
382 EXOSC6 118460
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
383 DDX41 51428
Affinity Capture-MS Homo sapiens
384 SLC4A1AP  
Affinity Capture-MS Homo sapiens
385 MAK16  
Affinity Capture-MS Homo sapiens
386 NARS 4677
Affinity Capture-MS Homo sapiens
387 IGKV2D-28 28883
Affinity Capture-MS Homo sapiens
388 RFX1  
Affinity Capture-MS Homo sapiens
389 CCAR2 57805
Affinity Capture-MS Homo sapiens
390 HSP90B1 7184
Affinity Capture-MS Homo sapiens
391 CCT5 22948
Affinity Capture-MS Homo sapiens
392 SRSF6 6431
Affinity Capture-MS Homo sapiens
393 NOC2L 26155
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
394 DDX5 1655
Affinity Capture-MS Homo sapiens
395 IFI16 3428
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
396 AP1B1 162
Affinity Capture-MS Homo sapiens
397 ZMPSTE24 10269
Affinity Capture-MS Homo sapiens
398 DDX54 79039
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
399 DDX1 1653
Affinity Capture-MS Homo sapiens
400 ZC3H15 55854
Affinity Capture-MS Homo sapiens
401 PRPF31 26121
Affinity Capture-MS Homo sapiens
402 CEBPA  
Protein-peptide Homo sapiens
403 ATP5B 506
Affinity Capture-MS Homo sapiens
404 GLTSCR2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
405 MAT2A 4144
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
406 SRSF11 9295
Affinity Capture-MS Homo sapiens
407 SFPQ 6421
Affinity Capture-MS Homo sapiens
408 BMS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
409 MRPL46  
Affinity Capture-MS Homo sapiens
410 PSMD13 5719
Affinity Capture-MS Homo sapiens
411 CCT6A 908
Affinity Capture-MS Homo sapiens
412 NAT10 55226
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
413 SRSF1 6426
Affinity Capture-MS Homo sapiens
414 RFC2 5982
Affinity Capture-MS Homo sapiens
415 RPL3 6122
Affinity Capture-MS Homo sapiens
416 RPP30 10556
Affinity Capture-MS Homo sapiens
417 MCM4 4173
Affinity Capture-MS Homo sapiens
418 RPL7 6129
Affinity Capture-MS Homo sapiens
419 SMU1 55234
Affinity Capture-MS Homo sapiens
420 SART1 9092
Affinity Capture-MS Homo sapiens
421 NXF1 10482
Affinity Capture-MS Homo sapiens
422 SF3A1 10291
Affinity Capture-MS Homo sapiens
423 JUN 3725
Affinity Capture-MS Homo sapiens
424 MAP7D1 55700
Affinity Capture-MS Homo sapiens
425 GLYR1 84656
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
426 DKC1 1736
Affinity Capture-MS Homo sapiens
427 DDX47 51202
Affinity Capture-MS Homo sapiens
428 DNAJC9 23234
Affinity Capture-MS Homo sapiens
429 SAMD9 54809
Affinity Capture-MS Homo sapiens
430 WDR75  
Affinity Capture-MS Homo sapiens
431 UPF3B 65109
Affinity Capture-MS Homo sapiens
432 SF3B3 23450
Affinity Capture-MS Homo sapiens
433 CSNK2A3 283106
Affinity Capture-MS Homo sapiens
434 NOL6 65083
Affinity Capture-MS Homo sapiens
435 DDX52  
Affinity Capture-MS Homo sapiens
436 MDM2  
Affinity Capture-MS Homo sapiens
437 RBBP4 5928
Affinity Capture-MS Homo sapiens
438 H2AFX 3014
Affinity Capture-MS Homo sapiens
439 PSMC3 5702
Affinity Capture-MS Homo sapiens
440 GTF3C4 9329
Affinity Capture-MS Homo sapiens
441 DHX15 1665
Affinity Capture-MS Homo sapiens
442 SPTAN1 6709
Affinity Capture-MS Homo sapiens
443 MINA 84864
Affinity Capture-MS Homo sapiens
444 NOL10  
Affinity Capture-MS Homo sapiens
445 Fbl 14113
Affinity Capture-MS Mus musculus
446 POLR1C 9533
Affinity Capture-MS Homo sapiens
447 SMARCC1 6599
Affinity Capture-MS Homo sapiens
448 NUFIP2 57532
Affinity Capture-MS Homo sapiens
449 BOP1 23246
Affinity Capture-MS Homo sapiens
450 HIST1H1E 3008
Affinity Capture-MS Homo sapiens
451 HIST1H2BD 3017
Cross-Linking-MS (XL-MS) Homo sapiens
452 NSA2  
Affinity Capture-MS Homo sapiens
453 OTUD4  
Affinity Capture-MS Homo sapiens
454 MOV10 4343
Affinity Capture-MS Homo sapiens
455 LRCH3 84859
Affinity Capture-MS Homo sapiens
456 UPF1 5976
Affinity Capture-MS Homo sapiens
457 RPS8 6202
Affinity Capture-MS Homo sapiens
458 GRSF1 2926
Affinity Capture-MS Homo sapiens
459 XRCC6 2547
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
460 HNRNPU 3192
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
461 GNB2L1 10399
Affinity Capture-MS Homo sapiens
462 IVNS1ABP  
Affinity Capture-MS Homo sapiens
463 EMG1 10436
Affinity Capture-MS Homo sapiens
464 CDC5L 988
Affinity Capture-MS Homo sapiens
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Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here