Gene description for CAMK2D
Gene name	calcium/calmodulin-dependent protein kinase II delta
Gene symbol	CAMK2D
Other names/aliases	CAMKD
Species	Homo sapiens
Database cross references - CAMK2D
ExoCarta	ExoCarta_817
Entrez Gene	817
HGNC	1462
MIM	607708
UniProt	Q13557
CAMK2D identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Colorectal cancer cells	23161513
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Thymus	23844026

Gene ontology annotations for CAMK2D

Molecular Function     sodium channel inhibitor activity GO:0019871 IDA     protein serine/threonine kinase activity GO:0004674 IDA     titin binding GO:0031432 IPI     ATP binding GO:0005524 IEA     ion channel binding GO:0044325 ISS     nitric-oxide synthase binding GO:0050998 IEA     protein binding GO:0005515 IPI     calmodulin binding GO:0005516 IPI     protein homodimerization activity GO:0042803 IPI     calmodulin-dependent protein kinase activity GO:0004683 IDA Biological Process     peptidyl-threonine phosphorylation GO:0018107 IDA     endoplasmic reticulum calcium ion homeostasis GO:0032469 ISS     regulation of heart contraction GO:0008016 TAS     positive regulation of smooth muscle cell migration GO:0014911 IEA     positive regulation of smooth muscle cell proliferation GO:0048661 IEA     regulation of heart rate by cardiac conduction GO:0086091 IC     peptidyl-serine phosphorylation GO:0018105 IDA     relaxation of cardiac muscle GO:0055119 ISS     interferon-gamma-mediated signaling pathway GO:0060333 TAS     cellular potassium ion homeostasis GO:0030007 IEA     protein autophosphorylation GO:0046777 IDA     protein phosphorylation GO:0006468 IDA     regulation of cardiac muscle cell action potential GO:0098901 ISS     cell growth involved in cardiac muscle cell development GO:0061049 IEA     regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion GO:0010881 TAS     regulation of cardiac muscle cell action potential involved in regulation of contraction GO:0098909 IC     regulation of G2/M transition of mitotic cell cycle GO:0010389 IEA     regulation of cellular localization GO:0060341 IMP     regulation of histone deacetylase activity GO:1901725 TAS     positive regulation of cardiac muscle hypertrophy GO:0010613 IMP     regulation of ryanodine-sensitive calcium-release channel activity GO:0060314 TAS     response to hypoxia GO:0001666 IEA     cytokine-mediated signaling pathway GO:0019221 TAS     G1/S transition of mitotic cell cycle GO:0000082 IEA     regulation of cell communication by electrical coupling GO:0010649 ISS     cellular response to calcium ion GO:0071277 TAS     synaptic transmission GO:0007268 TAS     negative regulation of sodium ion transmembrane transporter activity GO:2000650 IDA     regulation of the force of heart contraction GO:0002026 TAS     regulation of membrane depolarization GO:0003254 IDA     positive regulation of ERK1 and ERK2 cascade GO:0070374 IEA     regulation of cell growth GO:0001558 NAS     regulation of transcription from RNA polymerase II promoter GO:0006357 TAS     cellular response to heat GO:0034605 TAS     positive regulation of Rac protein signal transduction GO:0035022 IEA     regulation of relaxation of cardiac muscle GO:1901897 IDA     protein oligomerization GO:0051259 IDA     negative regulation of sodium ion transmembrane transport GO:1902306 IDA     regulation of cell communication by electrical coupling involved in cardiac conduction GO:1901844 IC     regulation of generation of L-type calcium current GO:1902514 ISS     regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum GO:0010880 ISS     cardiac muscle cell contraction GO:0086003 ISS     calcium ion transport GO:0006816 IEA     regulation of cellular response to heat GO:1900034 TAS Subcellular Localization     perinuclear region of cytoplasm GO:0048471 IEA     calcium channel complex GO:0034704 ISS     nucleus GO:0005634 ISS     cytoplasm GO:0005737 ISS     sarcoplasmic reticulum membrane GO:0033017 IEA     nucleoplasm GO:0005654 TAS     cytosol GO:0005829 TAS     intercalated disc GO:0014704 IEA     neuromuscular junction GO:0031594 IEA     plasma membrane GO:0005886 TAS     endocytic vesicle membrane GO:0030666 TAS     neuronal cell body GO:0043025 IEA     membrane GO:0016020 IDA     T-tubule GO:0030315 IEA     axon initial segment GO:0043194 IEA