Gene description for FTSJ2
Gene name FtsJ RNA methyltransferase homolog 2 (E. coli)
Gene symbol FTSJ2
Other names/aliases FJH1
HEL97
MRM2
RRMJ2
Species Homo sapiens
 Database cross references - FTSJ2
ExoCarta ExoCarta_29960
Entrez Gene 29960
HGNC 16352
MIM 606906
UniProt Q9UI43  
 FTSJ2 identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells 26054723    
 Gene ontology annotations for FTSJ2
Molecular Function
    rRNA (uridine-2'-O-)-methyltransferase activity GO:0008650 NAS
Biological Process
    cell proliferation GO:0008283 NAS
    rRNA processing GO:0006364 NAS
    rRNA methylation GO:0031167 NAS
Subcellular Localization
    mitochondrion GO:0005739 ISS
    nucleolus GO:0005730 IDA
 Experiment description of studies that identified FTSJ2 in exosomes
1
Experiment ID 236
ISEV standards
EM
EV Biophysical techniques
TSG101|Alix|HSC70|GAPDH
EV Cytosolic markers
EV Membrane markers
HSP90B1
EV Negative markers
qNano
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocellular carcinoma cells
Sample name MHCC97L
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
RNA
Methods used in the study Western blotting
Mass spectrometry
RT-PCR
RNA Sequencing
 Protein-protein interactions for FTSJ2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FTSJ2 is involved
No pathways found





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