Experiment description of studies that identified MANSC1 in exosomes

1 Experiment ID 834 MISEV standards ✔ EM Biophysical techniques ✔ LAMP2|CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

2 Experiment ID 835 MISEV standards ✔ EM Biophysical techniques ✔ CD63|FLOT1|ITGA2B|ICAM1|CD9|CD151|TFRC|RAB5A|GAPDH|AQP1|TSG101 Enriched markers ✔ CANX Negative markers ✔ NTA Particle analysis Identified molecule Protein Identification method Mass spectrometry PubMed ID 35333565     Organism Homo sapiens Experiment description LAMP2A regulates the loading of proteins into exosomes Authors Ferreira JV, da Rosa Soares A, Ramalho J, Máximo Carvalho C, Cardoso MH, Pintado P, Carvalho AS, Beck HC, Matthiesen R, Zuzarte M, Girão H, van Niel G, Pereira P Journal name Sci Adv Publication year 2022 Sample Retinal pigment epithelial cells Sample name ARPE-19 Isolation/purification methods Differential centrifugation Filtration Ultracentrifugation Flotation density - Molecules identified in the study Protein Methods used in the study Western blotting Mass spectrometry

Protein-protein interactions for MANSC1

Protein Interactor ExoCarta ID Identification method PubMed Species 1 RNF149 284996 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 2 ANKRD13C   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 3 PTPRF 5792 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 4 CLCN7 1186 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 5 SNX3 8724 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 6 LGR4 55366 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 7 VTI1B 10490 Affinity Capture-MS Homo sapiens 8 MBLAC2 153364 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 9 SACM1L 22908 Affinity Capture-MS Homo sapiens 10 PLEKHB1 58473 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 11 SLC35F5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 12 CMTM4   Affinity Capture-MS Homo sapiens 13 APOE 348 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 14 TAB1 10454 Affinity Capture-MS Homo sapiens 15 MAP4K4 9448 Affinity Capture-MS Homo sapiens 16 VSTM1   Two-hybrid Homo sapiens 17 LRP10 26020 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 18 SLC39A3   Affinity Capture-MS Homo sapiens 19 VANGL2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 20 ABCA3 21 Affinity Capture-MS Homo sapiens 21 MARK2 2011 Affinity Capture-MS Homo sapiens 22 ADCY6 112 Affinity Capture-MS Homo sapiens 23 SRC 6714 Affinity Capture-MS Homo sapiens 24 FTSJ2 29960 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 25 NOTCH3 4854 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 26 ACVR2B   Affinity Capture-MS Homo sapiens 27 TRAM2 9697 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 28 TOM1L1 10040 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 29 NMU   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 30 BET1 10282 Affinity Capture-MS Homo sapiens 31 MARK4   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 32 PKN3 29941 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 33 MYCN   Affinity Capture-MS Homo sapiens 34 SDCBP 6386 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 35 FGFR1 2260 Affinity Capture-MS Homo sapiens 36 PLEKHH3   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 37 NDFIP1 80762 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 38 NFRKB   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 39 TTYH2 94015 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 40 CCPG1 9236 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 41 TSPAN3 10099 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 42 ATP7B 540 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 43 ACVR1B 91 Affinity Capture-MS Homo sapiens 44 PIK3CB 5291 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 45 TP53I11   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 46 TAB2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 47 DNAJB9 4189 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 48 RNF13 11342 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 49 STX5 6811 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 50 DNAJB5   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 51 MVB12A 93343 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 52 TAF6L 10629 Affinity Capture-MS Homo sapiens 53 SLC12A9 56996 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 54 EPHB4 2050 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 55 USP32 84669 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 56 CDK17 5128 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 57 NUCB2 4925 Affinity Capture-MS Homo sapiens 58 RHBDD1 84236 Affinity Capture-MS Homo sapiens 59 RNF34   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 60 NRSN2   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 61 OCRL 4952 Affinity Capture-MS Homo sapiens 62 RNF130   Affinity Capture-MS Homo sapiens 63 VAMP3 9341 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 64 DIP2A 23181 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 65 POM121   Affinity Capture-MS Homo sapiens 66 KLRG2 346689 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 67 RABGAP1 23637 Affinity Capture-MS Homo sapiens 68 SBF1 6305 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 69 FAM63A 55793 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 70 EPHA7 2045 Affinity Capture-MS Homo sapiens 71 PI4K2B 55300 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 72 DIRAS1 148252 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 73 SNX17 9784 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 74 NUCB1 4924 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 75 RELT   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 76 RBM14-RBM4 100526737 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 77 FAM115C   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 78 RAB9A 9367 Affinity Capture-MS Homo sapiens 79 PIK3CA 5290 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 80 SIRT2 22933 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 81 WDR44 54521 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 82 KIDINS220 57498 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 83 OSMR 9180 Affinity Capture-MS Homo sapiens 84 DNAJC13 23317 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 85 MARK3 4140 Affinity Capture-MS Homo sapiens 86 ARRB2 409 Affinity Capture-MS Homo sapiens 87 GRK6 2870 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 88 HBA2 3040 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 89 CDC6   Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 90 BMPR1A 657 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 91 NISCH 11188 Affinity Capture-MS Homo sapiens 92 STARD3 10948 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 93 DAGLB 221955 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 94 PTPRS 5802 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 95 DDR1 780 Affinity Capture-MS Homo sapiens 96 DNAJB4 11080 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 97 LRP2 4036 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 98 SMPD2 6610 Affinity Capture-MS Homo sapiens 99 PIK3R2 5296 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 100 MYC   Affinity Capture-MS Homo sapiens 101 VANGL1 81839 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 102 JAK1 3716 Affinity Capture-MS Homo sapiens Affinity Capture-MS Homo sapiens 103 PIK3R3 8503 Affinity Capture-MS Homo sapiens View the network

Pathways in which MANSC1 is involved

No pathways found