Gene description for LRP10
Gene name low density lipoprotein receptor-related protein 10
Gene symbol LRP10
Other names/aliases LRP9
MST087
MSTP087
Species Homo sapiens
 Database cross references - LRP10
ExoCarta ExoCarta_26020
Entrez Gene 26020
HGNC 14553
MIM 609921
UniProt Q7Z4F1  
 LRP10 identified in exosomes derived from the following tissue/cell type
Prostate cancer cells 25844599    
 Gene ontology annotations for LRP10
Biological Process
    endocytosis GO:0006897 IEA
Subcellular Localization
    membrane GO:0016020 IDA
    integral component of membrane GO:0016021 IEA
    coated pit GO:0005905 IEA
 Experiment description of studies that identified LRP10 in exosomes
1
Experiment ID 275
ISEV standards
✔
EM
EV Biophysical techniques
✔
TSG101|Alix|RAB5A
EV Cytosolic markers
✔
CD9|CD82|CD63|CD81
EV Membrane markers
✔
AIF
EV Negative markers
✔
NTA
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25844599    
Organism Homo sapiens
Experiment description Molecular profiling of prostate cancer derived exosomes may reveal a predictive signature for response to docetaxel.
Authors Kharaziha P, Chioureas D, Rutishauser D, Baltatzis G, Lennartsson L, Fonseca P, Azimi A, Hultenby K, Zubarev R, Ullen A, Yachnin J, Nilsson S, Panaretakis T.
Journal name Oncotarget
Publication year 2015
Sample Prostate cancer cells
Sample name DU145 - Docetaxel sensitive
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.12-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry/Flow cytometry/Western blotting
 Protein-protein interactions for LRP10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LRP10 is involved
PathwayEvidenceSource
Retinoid metabolism and transport TAS Reactome





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here