Gene description for CSNK1G2
Gene name casein kinase 1, gamma 2
Gene symbol CSNK1G2
Other names/aliases CK1g2
Species Homo sapiens
 Database cross references - CSNK1G2
ExoCarta ExoCarta_1455
Vesiclepedia VP_1455
Entrez Gene 1455
HGNC 2455
MIM 602214
UniProt P78368  
 CSNK1G2 identified in exosomes derived from the following tissue/cell type
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
Bone marrow mesenchymal stem cells 36408942    
 Gene ontology annotations for CSNK1G2
Molecular Function
    protein serine/threonine kinase activity GO:0004674 IBA
    protein serine/threonine kinase activity GO:0004674 IDA
    protein serine/threonine kinase activity GO:0004674 TAS
    3-phosphoinositide-dependent protein kinase activity GO:0004676 IEA
    DNA-dependent protein kinase activity GO:0004677 IEA
    AMP-activated protein kinase activity GO:0004679 IEA
    eukaryotic translation initiation factor 2alpha kinase activity GO:0004694 IEA
    ribosomal protein S6 kinase activity GO:0004711 IEA
    protein binding GO:0005515 IPI
    ATP binding GO:0005524 IEA
    histone H3S10 kinase activity GO:0035175 IEA
    histone H3T11 kinase activity GO:0035402 IEA
    histone H3T6 kinase activity GO:0035403 IEA
    histone H2AXS139 kinase activity GO:0035979 IEA
    histone H3S28 kinase activity GO:0044022 IEA
    histone H4S1 kinase activity GO:0044023 IEA
    histone H2AS1 kinase activity GO:0044024 IEA
    histone H2BS14 kinase activity GO:0044025 IEA
    histone H3T3 kinase activity GO:0072354 IEA
    histone H2AS121 kinase activity GO:0072371 IEA
    Rho-dependent protein serine/threonine kinase activity GO:0072518 IEA
    protein serine kinase activity GO:0106310 IEA
    histone H2BS36 kinase activity GO:0140823 IEA
    histone H3S57 kinase activity GO:0140855 IEA
    histone H3T45 kinase activity GO:0140857 IEA
    histone H2AT120 kinase activity GO:1990244 IEA
Biological Process
    chromatin remodeling GO:0006338 IEA
    protein phosphorylation GO:0006468 TAS
    endocytosis GO:0006897 IBA
    signal transduction GO:0007165 IBA
    Wnt signaling pathway GO:0016055 IEA
    sphingolipid biosynthetic process GO:0030148 TAS
    positive regulation of canonical Wnt signaling pathway GO:0090263 IBA
Subcellular Localization
    nucleus GO:0005634 IBA
    cytoplasm GO:0005737 IBA
    cytosol GO:0005829 TAS
    plasma membrane GO:0005886 IBA
    cell cortex GO:0005938 IEA
    membrane GO:0016020 HDA
 Experiment description of studies that identified CSNK1G2 in exosomes
1
Experiment ID 489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 6
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
2
Experiment ID 490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 7
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
3
Experiment ID 491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 8
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
4
Experiment ID 492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Rattus norvegicus
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Bone marrow mesenchymal stem cells
Sample name BMSC - Passage 9
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for CSNK1G2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 KRTAP10-7  
Two-hybrid Homo sapiens
2 RNF149 284996
Affinity Capture-MS Homo sapiens
3 PTPRF 5792
Affinity Capture-MS Homo sapiens
4 FTL 2512
Affinity Capture-MS Homo sapiens
5 ANLN 54443
Affinity Capture-MS Homo sapiens
6 SLC20A1 6574
Affinity Capture-MS Homo sapiens
7 LRRIQ1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
8 RAP1GAP 5909
Two-hybrid Homo sapiens
9 SNX27 81609
Affinity Capture-MS Homo sapiens
10 DDR1 780
Affinity Capture-MS Homo sapiens
11 PER1  
Reconstituted Complex Homo sapiens
12 FGFR1 2260
Affinity Capture-MS Homo sapiens
13 ATP2B4 493
Affinity Capture-MS Homo sapiens
14 LAMTOR1 55004
Affinity Capture-MS Homo sapiens
15 BTNL9  
Affinity Capture-MS Homo sapiens
16 SDC1 6382
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 OPALIN  
Affinity Capture-MS Homo sapiens
18 KCNC3 3748
Affinity Capture-MS Homo sapiens
19 MTA1 9112
Two-hybrid Homo sapiens
Reconstituted Complex Homo sapiens
Reconstituted Complex Homo sapiens
Affinity Capture-Western Homo sapiens
20 APPBP2  
Two-hybrid Homo sapiens
21 HOXB5  
Affinity Capture-MS Homo sapiens
22 IL32  
Affinity Capture-MS Homo sapiens
23 ATL2 64225
Affinity Capture-MS Homo sapiens
24 TMEM255B  
Affinity Capture-MS Homo sapiens
25 G3BP1 10146
Affinity Capture-MS Homo sapiens
26 DBNDD2  
Two-hybrid Homo sapiens
27 C12orf43  
Affinity Capture-MS Homo sapiens
28 CSNK1G3 1456
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
29 GINS4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
30 CERS2 29956
Affinity Capture-MS Homo sapiens
31 TIGIT  
Affinity Capture-MS Homo sapiens
32 DCAF16 54876
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 FAXC  
Affinity Capture-MS Homo sapiens
34 CSNK1G1 53944
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
35 APP 351
Reconstituted Complex Homo sapiens
36 LRP10 26020
Affinity Capture-MS Homo sapiens
37 MCAM 4162
Proximity Label-MS Homo sapiens
38 Mta1  
Affinity Capture-MS Mus musculus
39 APEX1 328
Affinity Capture-RNA Homo sapiens
40 YES1 7525
Affinity Capture-MS Homo sapiens
41 PPP1R14A 94274
Reconstituted Complex Homo sapiens
42 KCNE3  
Affinity Capture-MS Homo sapiens
43 ACVR1B 91
Affinity Capture-MS Homo sapiens
44 TNFRSF10B 8795
Affinity Capture-MS Homo sapiens
45 NISCH 11188
Affinity Capture-MS Homo sapiens
46 PTPRS 5802
Affinity Capture-MS Homo sapiens
47 JAK1 3716
Affinity Capture-MS Homo sapiens
48 OGT 8473
Reconstituted Complex Homo sapiens
49 SORT1 6272
Affinity Capture-MS Homo sapiens
50 SMAD3 4088
Affinity Capture-Western Homo sapiens
Biochemical Activity Homo sapiens
Affinity Capture-Western Homo sapiens
51 KCNE4  
Affinity Capture-MS Homo sapiens
52 TMEM231 79583
Affinity Capture-MS Homo sapiens
53 EPHA2 1969
Affinity Capture-MS Homo sapiens
54 COL4A3BP 10087
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Two-hybrid Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 GINS1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 KRAS 3845
Proximity Label-MS Homo sapiens
57 GINS2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 MAPK14 1432
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
59 RUNDC3B  
Two-hybrid Homo sapiens
60 MRAP2  
Affinity Capture-MS Homo sapiens
61 GINS3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
62 C2orf44  
Two-hybrid Homo sapiens
63 MALL  
Affinity Capture-MS Homo sapiens
64 TMEM150A  
Affinity Capture-MS Homo sapiens
65 TMEM185A  
Affinity Capture-MS Homo sapiens
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