Gene description for DDR1
Gene name	discoidin domain receptor tyrosine kinase 1
Gene symbol	DDR1
Other names/aliases	CAK CD167 DDR EDDR1 HGK2 MCK10 NEP NTRK4 PTK3 PTK3A RTK6 TRKE
Species	Homo sapiens
Database cross references - DDR1
ExoCarta	ExoCarta_780
Entrez Gene	780
HGNC	2730
MIM	600408
UniProt	Q08345
DDR1 identified in exosomes derived from the following tissue/cell type
Bladder cancer cells	20224111
Ovarian cancer cells	23333927
Ovarian cancer cells	23333927
Saliva	19199708

Gene ontology annotations for DDR1

Molecular Function     protein tyrosine kinase collagen receptor activity GO:0038062 IDA     protein binding GO:0005515 IPI     transmembrane receptor protein tyrosine kinase activity GO:0004714 TAS     metal ion binding GO:0046872 IEA     collagen binding GO:0005518 IMP     ATP binding GO:0005524 IEA Biological Process     branching involved in mammary gland duct morphogenesis GO:0060444 IEA     regulation of extracellular matrix disassembly GO:0010715 IMP     mammary gland alveolus development GO:0060749 IEA     extracellular matrix organization GO:0030198 TAS     ear development GO:0043583 IEA     protein autophosphorylation GO:0046777 IDA     negative regulation of cell proliferation GO:0008285 IEA     wound healing, spreading of cells GO:0044319 IMP     regulation of cell growth GO:0001558 IEA     smooth muscle cell-matrix adhesion GO:0061302 IMP     smooth muscle cell migration GO:0014909 IMP     embryo implantation GO:0007566 IEA     regulation of cell-matrix adhesion GO:0001952 IEA     cell adhesion GO:0007155 TAS     peptidyl-tyrosine autophosphorylation GO:0038083 IDA     lactation GO:0007595 IEA     collagen-activated tyrosine kinase receptor signaling pathway GO:0038063 IMP Subcellular Localization     integral component of plasma membrane GO:0005887 IEA     extracellular exosome GO:0070062 IDA     extracellular space GO:0005615 IDA     plasma membrane GO:0005886 TAS     receptor complex GO:0043235 IDA