Gene description for SPACA1
Gene name sperm acrosome associated 1
Gene symbol SPACA1
Other names/aliases SAMP32
Species Homo sapiens
 Database cross references - SPACA1
ExoCarta ExoCarta_81833
Vesiclepedia VP_81833
Entrez Gene 81833
HGNC 14967
MIM 612739
UniProt Q9HBV2  
 SPACA1 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for SPACA1
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    acrosome assembly GO:0001675 IBA
Subcellular Localization
    inner acrosomal membrane GO:0002079 IEA
    acrosomal membrane GO:0002080 IBA
 Experiment description of studies that identified SPACA1 in exosomes
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for SPACA1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 UPK3BL 100134938
Affinity Capture-MS Homo sapiens
2 TYW1B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
3 EMP1  
Two-hybrid Homo sapiens
4 CD72  
Two-hybrid Homo sapiens
5 MTPAP 55149
Affinity Capture-MS Homo sapiens
6 HM13 81502
Affinity Capture-MS Homo sapiens
7 IFNGR1 3459
Affinity Capture-MS Homo sapiens
8 LTN1 26046
Affinity Capture-MS Homo sapiens
9 ITGA6 3655
Affinity Capture-MS Homo sapiens
10 TM2D3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
11 SLC25A14  
Affinity Capture-MS Homo sapiens
12 SLC20A1 6574
Affinity Capture-MS Homo sapiens
13 RPRM  
Two-hybrid Homo sapiens
14 FAM171A2 284069
Affinity Capture-MS Homo sapiens
15 EMP3 2014
Two-hybrid Homo sapiens
16 TRO  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
17 MAD2L2 10459
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
18 SEMA4C 54910
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
19 GIMAP5  
Two-hybrid Homo sapiens
20 SCARB1 949
Affinity Capture-MS Homo sapiens
21 TMEM140  
Two-hybrid Homo sapiens
22 ITFG3 83986
Affinity Capture-MS Homo sapiens
23 TNFSF9  
Affinity Capture-MS Homo sapiens
24 LRFN1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
25 SMAGP  
Two-hybrid Homo sapiens
26 ARFGEF2 10564
Affinity Capture-MS Homo sapiens
27 ESYT2 57488
Affinity Capture-MS Homo sapiens
28 MPZL2 10205
Affinity Capture-MS Homo sapiens
29 COMMD4 54939
Affinity Capture-MS Homo sapiens
30 DYNC2LI1 51626
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
31 MELK  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
32 GOLIM4 27333
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
33 NRSN1  
Two-hybrid Homo sapiens
34 NSG1  
Two-hybrid Homo sapiens
35 ANTXR1 84168
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
36 CACNG7  
Two-hybrid Homo sapiens
37 TMEM47 83604
Two-hybrid Homo sapiens
38 PLD1 5337
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
39 SIMC1  
Affinity Capture-MS Homo sapiens
40 MICU2 221154
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
41 PAM16  
Affinity Capture-MS Homo sapiens
42 ACVR1B 91
Affinity Capture-MS Homo sapiens
43 TTC21B 79809
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
44 SLC25A19  
Affinity Capture-MS Homo sapiens
45 NEK4  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
46 INTS7  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
47 SGCG 6445
Two-hybrid Homo sapiens
48 GK  
Affinity Capture-MS Homo sapiens
49 CLDN19  
Two-hybrid Homo sapiens
50 COMMD3 23412
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
51 ADCK1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
52 ITM2B 9445
Affinity Capture-MS Homo sapiens
53 MAP2K7 5609
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
54 HEATR6  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
55 SLC25A26  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
56 PLN  
Two-hybrid Homo sapiens
57 IMPA2 3613
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
58 TMEM30A 55754
Affinity Capture-MS Homo sapiens
59 DENND6A 201627
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
60 KIAA1244  
Affinity Capture-MS Homo sapiens
61 PCDH1 5097
Affinity Capture-MS Homo sapiens
62 ATP2B2 491
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
63 THSD7B  
Two-hybrid Homo sapiens
64 AP1M1 8907
Affinity Capture-MS Homo sapiens
65 COMMD2 51122
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
66 GBF1 8729
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
67 SERP2  
Two-hybrid Homo sapiens
68 KIRREL 55243
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
69 STAT1 6772
Affinity Capture-MS Homo sapiens
70 LSMEM2  
Two-hybrid Homo sapiens
71 GALNT11 63917
Affinity Capture-MS Homo sapiens
72 MPZL1 9019
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
73 AP1M2 10053
Affinity Capture-MS Homo sapiens
74 PMP22  
Two-hybrid Homo sapiens
75 CTXN3  
Two-hybrid Homo sapiens
76 BNIP3 664
Two-hybrid Homo sapiens
77 KIAA0368 23392
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
78 ATP6V0B 533
Two-hybrid Homo sapiens
79 BDH1 622
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
80 RAD51C  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
81 SLC22A18 5002
Affinity Capture-MS Homo sapiens
82 LMBRD2 92255
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
83 SMIM3  
Two-hybrid Homo sapiens
84 C17orf80 55028
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
85 SLC25A6 293
Affinity Capture-MS Homo sapiens
86 DNAJC19 131118
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
87 VPS13B  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
88 VPS52 6293
Affinity Capture-MS Homo sapiens
89 KIAA1586  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
90 RIF1  
Affinity Capture-MS Homo sapiens
91 TSPAN15 23555
Affinity Capture-MS Homo sapiens
92 TUBB3 10381
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
93 SLITRK5  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
94 STARD3 10948
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
95 FASTKD3  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
96 ATP6V0C 527
Two-hybrid Homo sapiens
97 TMEM126B 55863
Affinity Capture-MS Homo sapiens
98 DAGLB 221955
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
99 DDR1 780
Affinity Capture-MS Homo sapiens
100 DNM3 26052
Affinity Capture-MS Homo sapiens
101 TATDN2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
102 IPO13 9670
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
103 DTWD1  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
104 SERTM1  
Two-hybrid Homo sapiens
105 DCP2  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
106 RPP38 10557
Affinity Capture-MS Homo sapiens
107 SRR 63826
Affinity Capture-MS Homo sapiens
108 C14orf2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which SPACA1 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here