Gene ontology annotations for IMPA2
Experiment description of studies that identified IMPA2 in exosomes
1
Experiment ID
489
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 6
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
2
Experiment ID
490
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 7
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
3
Experiment ID
491
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
4
Experiment ID
492
MISEV standards
✔
EM
Biophysical techniques
✔
Cd9|Cd81|Cd63|Gapdh|Sdcbp|Lamp1|Aqp1|Rab5a|Icam1|Cd82|Itga2b|Tsg101|Lamp2|Rab35|Flot1|Flot2|Cd151|Rab5b|Tfrc|Uchl1
Enriched markers
✔
Canx
Negative markers
✔
NTA
Particle analysis
Identified molecule
Protein
Identification method
Mass spectrometry
PubMed ID
36408942
Organism
Rattus norvegicus
Experiment description
Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors
"Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name
Proteomics
Publication year
2023
Sample
Bone marrow mesenchymal stem cells
Sample name
BMSC - Passage 9
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Western blotting Mass spectometry
5
Experiment ID
234
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-C3
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
6
Experiment ID
236
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
MHCC97L
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
7
Experiment ID
211
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
cytochrome c|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
IGROV1
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
8
Experiment ID
212
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|EpCAM|TFRC
Enriched markers
✔
Cytochrome C|GOLGA2
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
23333927
Organism
Homo sapiens
Experiment description
Characterization and proteomic analysis of ovarian cancer-derived exosomes.
Authors
"Liang B, Peng P, Chen S, Li L, Zhang M, Cao D, Yang J, Li H, Gui T, Li X, Shen K."
Journal name
J Proteomics
Publication year
2013
Sample
Ovarian cancer cells
Sample name
OVCAR-3
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
1.09-1.15 g/mL
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for IMPA2
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
HNRNPH1
3187
Affinity Capture-RNA
Homo sapiens
2
PDCD6
10016
Co-fractionation
Homo sapiens
3
ERCC3
Affinity Capture-MS
Homo sapiens
4
HSPE1
3336
Co-fractionation
Homo sapiens
5
AAR2
25980
Affinity Capture-MS
Homo sapiens
6
IMPA2
3613
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
7
ALDOC
230
Co-fractionation
Homo sapiens
8
ADSS
159
Co-fractionation
Homo sapiens
9
PGLS
25796
Co-fractionation
Homo sapiens
10
C18orf21
Affinity Capture-MS
Homo sapiens
11
PABPC4
8761
Co-fractionation
Homo sapiens
12
MSN
4478
Co-fractionation
Homo sapiens
13
ARHGDIA
396
Co-fractionation
Homo sapiens
14
PINK1
Affinity Capture-MS
Homo sapiens
15
SCPEP1
59342
Co-fractionation
Homo sapiens
16
SH2D3A
Affinity Capture-MS
Homo sapiens
17
CSNK1A1
1452
Affinity Capture-MS
Homo sapiens
18
NHLRC2
374354
Affinity Capture-MS
Homo sapiens
19
PAICS
10606
Co-fractionation
Homo sapiens
20
GPX4
2879
Co-fractionation
Homo sapiens
21
NPPA
Affinity Capture-MS
Homo sapiens
22
ZC3HC1
Affinity Capture-MS
Homo sapiens
23
ZIC1
Affinity Capture-MS
Homo sapiens
24
RBFOX1
54715
Affinity Capture-MS
Homo sapiens
25
DUT
1854
Co-fractionation
Homo sapiens
26
PARK7
11315
Co-fractionation
Homo sapiens
27
KLRD1
Affinity Capture-MS
Homo sapiens
28
SPACA1
81833
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
29
SLC44A3
Two-hybrid
Homo sapiens
30
HSF2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
31
PTDSS1
9791
Affinity Capture-MS
Homo sapiens
32
RPE
Co-fractionation
Homo sapiens
33
GLO1
2739
Co-fractionation
Homo sapiens
34
TXN
7295
Co-fractionation
Homo sapiens
35
IMPA1
3612
Two-hybrid
Homo sapiens
Co-fractionation
Homo sapiens
Two-hybrid
Homo sapiens
Affinity Capture-MS
Homo sapiens
36
ARL3
403
Co-fractionation
Homo sapiens
37
RDX
5962
Co-fractionation
Homo sapiens
38
ZDHHC6
Affinity Capture-MS
Homo sapiens
39
TEFM
Affinity Capture-MS
Homo sapiens
40
SARAF
Affinity Capture-MS
Homo sapiens
41
ITPA
3704
Co-fractionation
Homo sapiens
42
TSPAN6
7105
Affinity Capture-MS
Homo sapiens
43
A4GNT
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
44
SERPINB8
5271
Co-fractionation
Homo sapiens
45
PLIN3
10226
Co-fractionation
Homo sapiens
46
ALDOA
226
Co-fractionation
Homo sapiens
47
NUDT3
11165
Affinity Capture-MS
Homo sapiens
48
STMN1
3925
Co-fractionation
Homo sapiens
49
UBA3
9039
Two-hybrid
Homo sapiens
Two-hybrid
Homo sapiens
50
CARHSP1
23589
Co-fractionation
Homo sapiens
51
NUDT9
53343
Co-fractionation
Homo sapiens
52
APTX
Affinity Capture-MS
Homo sapiens
53
UPK1A
11045
Affinity Capture-MS
Homo sapiens
54
FSCN1
6624
Affinity Capture-MS
Homo sapiens
Co-fractionation
Homo sapiens
55
PLD6
Affinity Capture-MS
Homo sapiens
56
CCR1
Affinity Capture-MS
Homo sapiens
57
NDST2
Affinity Capture-MS
Homo sapiens
58
TNFRSF14
Two-hybrid
Homo sapiens
59
STX17
55014
Affinity Capture-MS
Homo sapiens
60
CYCS
54205
Co-fractionation
Homo sapiens
61
RIPPLY3
Affinity Capture-MS
Homo sapiens
62
SOX2
Affinity Capture-MS
Homo sapiens
View the network
image/svg+xml
Pathways in which IMPA2 is involved