Gene description for ATP6V0B
Gene name
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
Gene symbol
ATP6V0B
Other names/aliases
ATP6F HATPL VMA16
Species
Homo sapiens
Database cross references - ATP6V0B
ExoCarta
ExoCarta_533
Vesiclepedia
VP_533
Entrez Gene
533
HGNC
861
MIM
603717
UniProt
Q99437
ATP6V0B identified in exosomes derived from the following tissue/cell type
Hepatocellular carcinoma cells
26054723
Hepatocytes
26054723
Gene ontology annotations for ATP6V0B
Experiment description of studies that identified ATP6V0B in exosomes
1
Experiment ID
235
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocellular carcinoma cells
Sample name
HKCI-8
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RT-PCR RNA Sequencing
2
Experiment ID
237
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|Alix|HSC70|GAPDH
Enriched markers
✔
HSP90B1
Negative markers
✔
qNano
Particle analysis
Identified molecule
mRNA
Identification method
RNA Sequencing
PubMed ID
26054723
Organism
Homo sapiens
Experiment description
Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors
"He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N"
Journal name
Carcinogenesis
Publication year
2015
Sample
Hepatocytes
Sample name
MIHA
Isolation/purification methods
Differential centrifugation Filtration Ultracentrifugation Sucrose density gradient
Flotation density
1.13-1.19 g/mL
Molecules identified in the study
Protein RNA
Methods used in the study
Western blotting Mass spectrometry RNA Sequencing
Protein-protein interactions for ATP6V0B
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
RIT1
6016
Negative Genetic
Homo sapiens
2
MS4A3
Two-hybrid
Homo sapiens
3
GJA8
Two-hybrid
Homo sapiens
4
MIP
Two-hybrid
Homo sapiens
5
FAS
355
Two-hybrid
Homo sapiens
6
INSIG2
Two-hybrid
Homo sapiens
7
EMP1
Two-hybrid
Homo sapiens
8
TM4SF19
Two-hybrid
Homo sapiens
9
YWHAE
7531
Reconstituted Complex
Homo sapiens
10
ADRB2
Two-hybrid
Homo sapiens
11
GLP1R
PCA
Homo sapiens
Affinity Capture-Western
Homo sapiens
12
GPR97
Two-hybrid
Homo sapiens
13
MTNR1B
Two-hybrid
Homo sapiens
14
NRM
11270
Two-hybrid
Homo sapiens
15
STOM
2040
Two-hybrid
Homo sapiens
16
DDX58
23586
Affinity Capture-RNA
Homo sapiens
17
TMEM242
Two-hybrid
Homo sapiens
18
SPACA1
81833
Two-hybrid
Homo sapiens
19
NXF1
10482
Affinity Capture-RNA
Homo sapiens
20
MFF
56947
Two-hybrid
Homo sapiens
21
APOD
347
Two-hybrid
Homo sapiens
22
GPR42
Two-hybrid
Homo sapiens
23
MOV10
4343
Affinity Capture-RNA
Homo sapiens
24
SREBF2
6721
Negative Genetic
Homo sapiens
25
COL4A5
Two-hybrid
Homo sapiens
26
SLC10A1
Two-hybrid
Homo sapiens
27
SLC2A5
6518
Two-hybrid
Homo sapiens
28
GPR61
Two-hybrid
Homo sapiens
29
KRAS
3845
Negative Genetic
Homo sapiens
30
VMA21
Two-hybrid
Homo sapiens
31
KLRC1
Two-hybrid
Homo sapiens
32
YWHAG
7532
Two-hybrid
Homo sapiens
33
IRAK3
11213
Two-hybrid
Homo sapiens
34
FAM210B
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which ATP6V0B is involved