Gene description for SLC2A5
Gene name
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
Gene symbol
SLC2A5
Other names/aliases
GLUT-5 GLUT5
Species
Homo sapiens
Database cross references - SLC2A5
ExoCarta
ExoCarta_6518
Vesiclepedia
VP_6518
Entrez Gene
6518
HGNC
11010
MIM
138230
UniProt
P22732
SLC2A5 identified in exosomes derived from the following tissue/cell type
Urine
15326289
Urine
19056867
Urine
21595033
Urine
21595033
Urine
21595033
Urine
22418980
Urine
22418980
Gene ontology annotations for SLC2A5
Experiment description of studies that identified SLC2A5 in exosomes
1
Experiment ID
13
MISEV standards
✔
IEM
Biophysical techniques
✔
Alix|RAB4|RAB5B|RAB11|TSG101|CD9|AQP2|AQP1
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
15326289
Organism
Homo sapiens
Experiment description
Identification and proteomic profiling of exosomes in human urine.
Authors
"Pisitkun T, Shen RF, Knepper MA"
Journal name
PNAS
Publication year
2004
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Ultracentrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LCQ DECA XP] Western blotting
2
Experiment ID
63
MISEV standards
✘
Biophysical techniques
✔
AQP2
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
19056867
Organism
Homo sapiens
Experiment description
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Authors
"Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA"
Journal name
JASN
Publication year
2009
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry [LTQ] Western blotting
3
Experiment ID
193
MISEV standards
✔
EM
Biophysical techniques
✔
CD63|CD9
Enriched markers
✔
PHB
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
21595033
Organism
Homo sapiens
Experiment description
Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors
"Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name
Proteomics
Publication year
2011
Sample
Urine
Sample name
Urine - Normal
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
4
Experiment ID
194
MISEV standards
✘
Biophysical techniques
✘
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
21595033
Organism
Homo sapiens
Experiment description
Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors
"Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name
Proteomics
Publication year
2011
Sample
Urine
Sample name
Urine - Patients of basement membrane nephropathy
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
5
Experiment ID
195
MISEV standards
✘
Biophysical techniques
✘
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
21595033
Organism
Homo sapiens
Experiment description
Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy.
Authors
"Moon PG, Lee JE, You S, Kim TK, Cho JH, Kim IS, Kwon TH, Kim CD, Park SH, Hwang D, Kim YL, Baek MC."
Journal name
Proteomics
Publication year
2011
Sample
Urine
Sample name
Urine - Patients of early IgA nephropathy
Isolation/purification methods
Differential centrifugation Ultracentrifugation Sucrose density gradient
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
6
Experiment ID
196
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
22418980
Organism
Homo sapiens
Experiment description
A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors
"Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name
Kidney Int
Publication year
2012
Sample
Urine
Sample name
Urine - Normal high density
Isolation/purification methods
Differential centrifugation Sucrose cushion
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
7
Experiment ID
197
MISEV standards
✔
EM
Biophysical techniques
✔
Alix|TSG101|HSP70|CD9
Enriched markers
✘
Negative markers
✘
Particle analysis
Identified molecule
protein
Identification method
Mass spectrometry
PubMed ID
22418980
Organism
Homo sapiens
Experiment description
A multiplex quantitative proteomics strategy for protein biomarker studies in urinary exosomes.
Authors
"Raj DA, Fiume I, Capasso G, Pocsfalvi G."
Journal name
Kidney Int
Publication year
2012
Sample
Urine
Sample name
Urine - Normal low density
Isolation/purification methods
Differential centrifugation Sucrose cushion
Flotation density
-
Molecules identified in the study
Protein
Methods used in the study
Mass spectrometry
Protein-protein interactions for SLC2A5
Protein Interactor
ExoCarta ID
Identification method
PubMed
Species
1
RPSA
3921
Two-hybrid
Homo sapiens
2
LMBRD2
92255
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
3
ALDH1L1
10840
Affinity Capture-MS
Homo sapiens
4
MTERF3
Two-hybrid
Homo sapiens
5
FITM2
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
6
ATP2B2
491
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
7
FCRL3
Two-hybrid
Homo sapiens
8
OSBPL6
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
9
ATP12A
479
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
10
TCF7L2
Co-localization
Homo sapiens
11
CCL5
6352
Two-hybrid
Homo sapiens
12
SLC7A3
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
13
EVI2B
2124
Two-hybrid
Homo sapiens
14
TMEM237
65062
Two-hybrid
Homo sapiens
15
LPGAT1
9926
Affinity Capture-MS
Homo sapiens
16
FTO
79068
Affinity Capture-MS
Homo sapiens
17
TMEM130
Two-hybrid
Homo sapiens
18
ZMPSTE24
10269
Affinity Capture-MS
Homo sapiens
19
KIAA0368
23392
Affinity Capture-MS
Homo sapiens
20
ATP6V0B
533
Two-hybrid
Homo sapiens
21
ARL13B
200894
Two-hybrid
Homo sapiens
22
RBFOX3
Affinity Capture-MS
Homo sapiens
Affinity Capture-MS
Homo sapiens
23
SCN3B
Two-hybrid
Homo sapiens
24
MGST3
4259
Two-hybrid
Homo sapiens
View the network
image/svg+xml
Pathways in which SLC2A5 is involved