Gene description for MAP2K7
Gene name	mitogen-activated protein kinase kinase 7
Gene symbol	MAP2K7
Other names/aliases	JNKK2 MAPKK7 MEK MEK 7 MKK7 PRKMK7 SAPKK-4 SAPKK4
Species	Homo sapiens
Database cross references - MAP2K7
ExoCarta	ExoCarta_5609
Vesiclepedia	VP_5609
Entrez Gene	5609
HGNC	6847
MIM	603014
UniProt	O14733
MAP2K7 identified in exosomes derived from the following tissue/cell type
Thymus	23844026

Gene ontology annotations for MAP2K7

Molecular Function     magnesium ion binding GO:0000287 IDA     MAP kinase activity GO:0004707 IEA     MAP kinase kinase activity GO:0004708 IDA     protein binding GO:0005515 IPI     ATP binding GO:0005524 IEA     JUN kinase kinase activity GO:0008545 IBA     JUN kinase kinase activity GO:0008545 ISS     JUN kinase kinase activity GO:0008545 TAS     enzyme binding GO:0019899 IPI     protein kinase binding GO:0019901 IPI     protein phosphatase binding GO:0019903 ISS     histone H3Y41 kinase activity GO:0035401 IEA     protein serine kinase activity GO:0106310 IEA     molecular function activator activity GO:0140677 EXP     histone H2AXY142 kinase activity GO:0140801 IEA Biological Process     chromatin remodeling GO:0006338 IEA     apoptotic process GO:0006915 IEA     response to osmotic stress GO:0006970 IDA     signal transduction GO:0007165 TAS     JNK cascade GO:0007254 ISS     JNK cascade GO:0007254 TAS     response to heat GO:0009408 IDA     response to UV GO:0009411 IDA     response to wounding GO:0009611 IEA     positive regulation of telomere maintenance GO:0032206 IMP     response to tumor necrosis factor GO:0034612 IDA     Fc-epsilon receptor signaling pathway GO:0038095 TAS     positive regulation of JUN kinase activity GO:0043507 ISS     positive regulation of DNA-templated transcription GO:0045893 IMP     positive regulation of JNK cascade GO:0046330 IEA     stress-activated MAPK cascade GO:0051403 IBA     stress-activated MAPK cascade GO:0051403 IDA     positive regulation of ERK1 and ERK2 cascade GO:0070374 IMP     cellular response to lipopolysaccharide GO:0071222 IEA     cellular response to interleukin-1 GO:0071347 IEA     cellular senescence GO:0090398 TAS     regulation of motor neuron apoptotic process GO:2000671 IEA Subcellular Localization     nucleus GO:0005634 ISS     cytoplasm GO:0005737 ISS     cytosol GO:0005829 TAS